The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. We have focused on the cleavage specificities of HIV-1 protease, HCV NS3 protease and caspases on short oligopeptides or in native prote

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Execution trace graph analysis of dataflow programs has been demonstrated to be an effective way for exploring and optimizing the design space of many core applications. In this work a novel transformation from the execution trace graph to an event driven linear system is proposed. It is also illustrated how the trace space of can be effectively reduced and well known system control techniques can

The development of biodegradable polymers from renewable resources is of importance in order to prevent the depletion of fossil fuels and the increasing emissions of carbon dioxide to the atmosphere caused by the commodity plastics of today. However, to be able to replace these non-environmentally friendly materials, production costs of biodegradable polymers have to be decreased and their physica

The effects of the phase lag on the suspended load in the ripple regime were investigated for oscillatory flows and combined steady and unsteady flows. The Camenen et al. (2005) suspended load formula was modified in order to take into account both current-related and wave-related sediment transport. A particular effort was made to better predict the phase-lag effects in the ripple regime. The mod

Wild bank voles (Clethrionomys glareolus) may develop diabetes in laboratory captivity. The aim of this study was to test whether bank voles develop type 1 diabetes in association with Ljungan virus. Two groups of bank voles were analyzed for diabetes, pancreas histology, autoantibodies to glutamic acid decarboxylase (GAD65), IA-2, and insulin by standardized radioligand-binding assays as well as

This letter presents computationally efficient time-updating algorithms of the recent Iterative Adaptive Approach (IAA) spectral estimation technique. By exploiting the inherently low displacement rank, together with the development of suitable Gohberg-Semencul (GS) representations, and the use of data dependent trigonometric polynomials, the proposed time-recursive IAA algorithm offers a reductio

Hitherto collected data on more than hundred α-decay chains stemming from element 115 are combined to probe some aspects of the underlying nuclear structure of the heaviest atomic nuclei yet created in the laboratory.

Popular Abstract in Swedish Värk i leder och muskler tillhör de vanligaste orsakerna till långtidssjukskrivningar och förtidspensioneringar. En betydande del av dessa tillstånd är orsakade av belastningsergonomiska faktorer i arbetslivet, och kan således förebyggas. Arbetsrelaterade besvär i nacke, axlar och armar är betydligt vanligare bland kvinnor än bland män. Orsakerna till detta är ofullstänWork-related musculoskeletal disorders are widespread, and are, for unclear reasons, more common among females than in males. Several risk factors have been described; constrained and awkward postures, repetitive and/or force demanding motions, and lack of recovery. The exposure to such risk factors was systematically assessed in 116 male and 206 female fish-processing industry workers. Large diff