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Effects of cardiovascular pharmacotherapies on incident dementia in patients with atrial fibrillation : A cohort study of all patients above 45 years diagnosed with AF in hospitals in Sweden

Background: Patients with atrial fibrillation (AF) have an increased dementia risk dementia. We aimed to study the effect of antihypertensive drugs on dementia in AF patients. Methods: Included patients were ≥45 years diagnosed with AF in Swedish National Patient Register (n = 160,251; 89,723 men and 70,528 women) and alive on January 1, 2007. We excluded patients with dementia before onset of AF.

Controls on Dissolved Organic Carbon Bioreactivity in River Systems

Inland waters transport, transform and retain significant amounts of dissolved organic carbon (DOC) that may be biologically reactive (bioreactive) and thus potentially degraded into atmospheric CO2. Despite its global importance, relatively little is known about environmental controls on bioreactivity of DOC as it moves through river systems with varying water residence time (WRT). Here we determ

Thermal structure and evolution of an Archean large hot orogen : Insights from the Tasiusarsuaq terrane, SW Greenland

The Tasiusarsuaq terrane represents an Archean continental upper plate that was assembled and thickened by a series of igneous and tectonic events between c. 2970 and 2700 Ma. A review of the available data combined with thermodynamic modelling and U-Pb titanite and zircon dating allows detailed insight into the processes of crustal growth during the Meso- and Neoarchean. Following the intrusion o

Water Inhibition in Methane Oxidation over Alumina Supported Palladium Catalysts

In situ diffuse reflectance infrared Fourier transform spectroscopy has been used to distinguish surface hydroxyl groups on Al2O3 and PdO/Al2O3 model catalysts calcined at 500-900 °C. Employing the operando approach, the formation of surface hydroxyl groups has been correlated to the methane oxidation activity for PdO/Al2O3 catalysts using a PdO powder sample as reference. The results show that th

Clinical impact of T cells, B cells and the PD-1/PD-L1 pathway in muscle invasive bladder cancer : a comparative study of transurethral resection and cystectomy specimens

In patients with muscle invasive bladder cancer (MIBC), neoadjuvant chemotherapy (NAC) prior to radical cystectomy has improved survival but there is an urgent unmet need to identify prognostic and predictive biomarkers to stratify patients who will benefit from treatment. This study aimed to examine the composition of tumor-infiltrating immune cells in MIBC, with particular reference to the clini

Resolving Rotational Stacking Disorder and Electronic Level Alignment in a 2D Oligothiophene-Based Lead Iodide Perovskite

Two-dimensional (2D) hybrid organic-inorganic perovskites (HOIPs) represent diverse quantum well heterostructures composed of alternating inorganic and organic layers. While 2D HOIPs are nominally periodic in three dimensions for X-ray scattering, the inorganic layers can orient quasi-randomly, leading to rotational stacking disorder (RSD). RSD manifests as poorly resolved, diffuse X-ray scatterin

Phenotype prediction accuracy – A Swedish perspective

Methods for SNP-based phenotype prediction have recently been developed, but prediction accuracy data for several populations and regions are missing. We analysed the accuracy of hair and eye colour predictions for 111 individuals residing in Sweden, using the ForenSeq system and the MiSeq FGx instrument (Verogen). Observed colours were compared to predicted colours, using the colour with the high

Tumor Characteristics and Molecular Subtypes in Breast Cancer Screening with Digital Breast Tomosynthesis : The Malmö Breast Tomosynthesis Screening Trial

Background Screening accuracy can be improved with digital breast tomosynthesis (DBT). To further evaluate DBT in screening, it is important to assess the molecular subtypes of the detected cancers. Purpose To describe tumor characteristics, including molecular subtypes, of cancers detected at DBT compared with those detected at digital mammography (DM) in breast cancer screening. Materials and Me

Celebrities, air travel, and social norms

The year 2018 saw the rise of a new global youth movement, Fridays for Future. The organization underlines the importance of personal accountability for greenhouse gas emissions, specifically in the context of air travel. This position is in stark contrast to views associating aeromobility with status. Celebrities in particular maintain personal brands based on frequent flying. This paper assesses

Modeling Microgels with a Controlled Structure across the Volume Phase Transition

Thermoresponsive microgels are soft colloids that find widespread use as model systems for soft matter physics. Their complex internal architecture, made of a disordered and heterogeneous polymer network, has been so far a major challenge for computer simulations. In this work, we put forward a coarse-grained model of microgels whose structural properties are in quantitative agreement with results

Effect of hydrogen chloride etching on carrier recombination processes of indium phosphide nanowires

Introduction of in situ HCl etching to an epitaxial growth process has been shown to suppress radial growth and improve the morphology and optical properties of nanowires. In this paper, we investigate the dynamics of photo-generated charge carriers in a series of indium phosphide nanowires grown with varied HCl fluxes. Time resolved photo-induced luminescence, transient absorption and time resolv

Impact of carbon deposition on diffusion parameters in porous anodes of solid oxide fuel cells using the lattice Boltzmann method

A solid oxide fuel cell (SOFC) is an electrochemical device that converts energy of a chemical reaction into electrical and thermal energy. Besides lack of pollutants and high electrical efficiency, one of the main advantages of SOFCs is the flexibility of using a wide range of fuels, i.e., natural gas, biogas, or any reactant with hydrogen as constituent. However, the use of hydrocarbon fuels can

Empirical correlations for the performance of a PEFC considering relative humidity of fuel and oxidant gases

The growing energy demand and the impact of polluting gases lead to the necessity of alternative energy sources and conversion energy devices. Fuel cells (FCs) appears as a suitable solution for facing the mentioned issues. Predicting the behavior of a polymer electrolyte fuel cell (PEFC) under different conditions represents a proper initial step to solve the several issues, e.g., aging water bal

A role for hepatic lipase in chylomicron and high density lipoprotein phospholipid metabolism

The rate of removal of phosphatidylethanolamine and phosphatidylcholine from the plasma of rats treated with antiserum to hepatic lipase was measured. The hepatic lipase antiserum was injected intravenously into animals prior to injection of 32P-labeled chylomicrons or 32P-labeled high density lipoproteins. In experiments in which 32P-labeled chylomicrons were injected, antiserum treatment inhibit

Health-related quality of life and glycaemic control among adults with type 1 and type 2 diabetes - A nationwide cross-sectional study

Background: Health-related quality of life and glycaemic control are some of the central outcomes in clinical diabetes care and research. The purpose of this study was to describe the health-related quality of life and assess its association with glycaemic control in adults with type 1 and type 2 diabetes in a nationwide setting. Methods: In this cross-sectional survey, people with type 1 (n = 247

Arachidonic acid absorption in human jejunum in organ culture : effects of ethanol

Human jejunal tissue obtained by peroral biopsy was cultured in control medium and in medium containing 100 mmol l-1 ethanol. Subsequently, the incorporation and metabolism of [3H]-arachidonic and [14C]-linoleic acid were evaluated. Of the two fatty acids a significantly higher amount of [3H]-arachidonic acid was incorporated into phospholipids and more [14C]-linoleic acid was incorporated into tr