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OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systoli
In this paper we show that the long-run stock and bond volatility and the long-run stock-bond correlation depend on macroeconomic uncertainty. We use the mixed data sampling (MIDAS) econometric approach. The findings are in accordance with the flight-to-quality phenomenon when macroeconomic uncertainty is high. (C) 2015 Elsevier Inc. All rights reserved.
Aluminum foams are favorable in modern thermal engineering applications because of the high thermal conductivity and the large specific surface area. The present study aims to investigate an application of porous aluminum foam by using the local thermal equilibrium (LTE) and local thermal nonequilibrium (LTNE) heat transfer models. Three-dimensional simulations of laminar flow (porous foam zone),
Aims/hypothesis The role of biomarkers of subclinical inflammation in the early deterioration of glycaemia before type 2 diabetes is largely unknown. We hypothesised that increased levels of circulating proinflammatory biomarkers and decreased circulating adiponectin would be associated with 7 year increases of HbA(1c) in non-diabetic individuals. Methods This study was based on individuals who pa
The hygroscopic growth of the atmospheric aerosol is a critical parameter for quantifying the anthropogenic radiative forcing. Until now, there has been a lack of long term measurements due to limitations in instrumental techniques. In this work, for the first time the seasonal variation of the hygroscopic properties of a continental background aerosol has been described, based on more than two ye
Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of asthma, and neutralization of TNF-alpha is an effective therapy for inflammatory diseases. The present study tested the idea that a TNF-alpha antibody, infliximab, may be useful in the management of asthma. E3 rats were immunized with ovalbumin (OVA)/alum and received infliximab intra-peritoneally. Two weeks later,
The performance of the current quantum dot (QD) solar cells is limited by several deficiencies. One of them is the existence of surface traps, especially hole traps, which are blocking the hole injection into the electrolyte. The trapping can be efficiently suppressed by growing a shell of wider band gap material around the core dot. Optimum parameters of such a shell layer for photovoltaic applic
The aim of this study was to investigate the groundwater chemistry with special concern to metal pollution in selected communities in the Wassa West district, Ghana. In this mining area, 40 ground water samples, mainly from drilled wells, were collected. The groundwaters have generally from neutral to acidic pH values and their Eh values indicate oxidising conditions. The dominating ions are calci
Staphylococcus aureus strains producing the bacteriophage-encoded staphylococcal enterotoxin A (SEA) were divided into two groups, high- and low-SEA-producing strains, based on the amount of SEA produced. After growth under favorable conditions in batch cultures, ten of the 21 strains tested produced more than 1,000 ng/ml SEA and nine strains produced less than 10 ng/ml SEA; two enterotoxigenic st
While researchers agree that note passing is predominantly an activity engaged in by girls, there has been relatively little consideration of why this is the case. In this article, I argue that gendered expectations about the appropriate characters of boys and girls in Vietnam are incorporated into the disciplinary framework of schools, and that note passing provides the means for girls to adjust
Factors affecting serum prostate-specific antigen (PSA) levels in men are clinically important, but apart from effects mediated through the androgen receptor, they are poorly understood.
Mutation status of FLT3, NPM1, CEBPA, and WT1 genes and gene expression levels of ERG, MN1, BAALC, FLT3, and WT1 have been identified as possible prognostic markers in acute myeloid leukemia (AML). We have performed a thorough prognostic evaluation of these genetic markers in patients with pediatric AML enrolled in the Nordic Society of Pediatric Hematology and Oncology (NOPHO) 1993 or NOPHO 2004
In this study we aimed to evaluate effects of liver resection on hepatic microcirculation. In addition we wanted to study if histological liver damage could be detected intra-operatively.
It is argued that normativity is an embodied and situated skill that resists explanation in terms of rule-following. Norms are dynamic and negotiable, and are understood in practice by engaging with others. Rules are a subclass of norms and have pragmatic functions, e.g. to impose norms and elucidate implicit normativity. The propositional articulation of norms is secondary to normativity. Norms c
Frontotemporal dementia (FTD) is a complex disorder characterised by a broad range of clinical manifestations, differential pathological signatures, and genetic variability. Mutations in three genes-MAPT, GRN, and C9orf72-have been associated with FTD. We sought to identify novel genetic risk loci associated with the disorder.
AimsThe effects of sitagliptin and pioglitazone, alone and in combination, on - and -cell function were assessed in patients with type 2 diabetes. MethodsFollowing a 6-week diet/exercise period, 211 patients with HbA1c of 6.5-9.0% and fasting plasma glucose of 7.2-14.4mmol/l were randomized (1:1:1:1) to sitagliptin, pioglitazone, sitagliptin+pioglitazone or placebo. At baseline and after 12weeks,
An accurate characterization of the microstructure of raw and pure homoionic clays from Wadi Bashira in Iraq (IQ-WB) has been carried out experimentally, using small-angle X-ray scattering (SAXS) and dynamic light scattering. The structures of lamellar IQ-WB dispersions were identified by these techniques and by complementary free swelling and dialysis experiments. SAXS measurements were used to r
Urinary tract infections (UTIs) and male genital infections are amongst the most prevalent infections. A prudent antibiotic policy therefore has a large impact on society. The clinical classification in uncomplicated cystitis, uncomplicated pyelonephritis, complicated UTI and genital infections is useful, also for the right choice of antibiotic treatment. In this regard pharmacokinetic and pharmac
