This paper considers off-line optimization of a switching sequence fora given finite set of linear control systems, together with joint optimization ofcontrol laws. A linear quadratic full information criterion isoptimized and dynamic programming is used to find an optimalswitching sequence and control law. The main result is a method forefficient pruning of the search tree to avoid combinatoric e

The aim of this thesis was to identify novel potential drug targets of cardiovascular disease with a focus on G-protein coupled receptors. We identified a common genetic variant of the ATP receptor P2Y11, where an alanine is substituted with a threonine at position 87 of the P2Y11 receptor that increases the risk of developing acute myocardial infarction. Also, the Thr-87 variant of P2Y11 is asso

Background: Oxidation of LDL is associated with generation of autoantibodies against a large number of different aldehyde-modified peptide sequences in apo B-100. Autoantibodies recognizing peptide sequences in the LDL receptor-binding region of apo B-100 could potentially affect both cholesterol metabolism and atherosclerosis. The aim of the present study was to determine physiological effects of

Anthraldehyde acetals can be introduced regioselectively to carbohydrates in high yields. Advantages over conventional acetal protecting groups are increased crystallinity and strong absorbance and fluorescence which facilitate purification and reaction monitoring. The anthraldehyde acetals can be deprotected selectively in the presence of benzylidene acetals and can be cleaved regioselectively to

Objective: The present study examined whether socio-economic status (SES) of the family of origin, inadequate parenting, and pro and perinatal factors are antecedents of criminality among men and women who develop a major mental disorder. Method: The sample included the 82 men and 79 women from the 1953 Stockholm birth cohort who developed a major mental disorder by age 30. Information was extract

Injection of the superantigen staphylococcal enterotoxin A (SEA) activates both CD4+ and CD8+ T cells expressing certain families of T cell receptor (TCR) variable-region beta (V beta) chain. T cells respond with profound cytokine production and induction of cytotoxicity. Repeated injections, however, cause deletion and anergy of both CD4+ and CD8+ T cells, resulting in reduced frequency of SEA-re

BACKGROUND: Individuals with low income have poorer health and should, therefore, have higher health expenditure than people with high income particularly in countries with a universal health care system. However, it has been discussed if social inequities in health diminish with age and we, hence, aimed to analyse this question. METHODS: We performed an age stratified cross-sectional analysis usi

Pharyngeal function was studied in 31 patients with rheumatoid arthritis. Eighteen of these patients had dysphagia. Cervical spine abnormalities were present in 14. Destruction of the capitulum and/or ramus of the mandible was registered in 9. Pharyngeal dysfunction was revealed in 20. Patients with a vertical dislocation of the C1-C2 in relation to the occipital bone and patients with destruction

Popular Abstract in Swedish Åderförfettning (även kallat åderförkalkning eller ateroskleros) börjar genom att det ?onda kolesterolet? LDL fastnar i väggen på ett blodkärl. Där kan LDL börja modifieras och orsaka inflammation. Inflammationen påskyndas av att vita blodceller kommer in i artärväggen och försöker ta bort fettet. Om en stor mängd fett lagras in, kan det inte avlägsnas. Tillsammans med Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. The rupture of the atherosclerotic plaques, foll

Abstract is not available

The results of three ultra-wideband (UWB) measurement campaigns conducted in two different industrial environments are presented. A frequency range of 3.1 - 10.6 or 3.1 - 5.5 GHz was measured using a vector network analyzer and a virtual array technique enabling the investigation of smallscale statistics. The results show that the energy arrives in clusters, and that the abundance of metallic scat

We have found a (dense) basis for the N-representable, two-electron densities, in which all N-representable two-electron densities can be expanded, using positive coefficients. The inverse problem of finding a representative wavefunction, giving a prescribed two-electron density, has also been solved. The two-electron densities are found to lie in a convex set in a vector space. An algorithm to co

Results from a Monte Carlo investigation of the dual photopeak window (DPW) scatter correction method are presented for point and extended sources of Tc-99m in both homogeneous and nonhomogeneous attenuating media. The DPW method uses the ratio of counts in two nonoverlapping energy windows within the photopeak region as input to a regression relation. A pixel-by-pixel estimate of the scatter in t

It is widely recognized that judicial independence is an indispensable value of a modern democracy. When a country wishes to adopt this value, questions may arise, such as what it is and how to develop it properly? This thesis explores the issue of judicial independence in two aspects: theoretical and practical. For the theoretical aspect, it first examines the rule of law and protection of human

Personality, mental distress, and risk perception were assessed in (a) cases of multiple chemical sensitivity (MCS; n = 17), (b) chemically intolerant toxic encephalopathy cases (TE), type 2A (n = 31) and 2B (n = 26), and (c) healthy referents (n = 200). MCS cases showed elevated mental distress scores on the Depression, Interpersonal Sensitivity, Global Severity Index, and Somatization scales in

The research in the Department of Physical Chemistry 1 at Lund University includes topics such as surfactant self-assembly; polymers, solutions, gels and phase behavior, polymer-surfactant systems; protein and protein-amphiphile systems; adsorption and surface forces; experimental methodology in colloid science; and theory and modeling. (Annual Report (2004) Physical Chemistry 1; Lund University;