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Predictors of the Need for an Atrial Septal Defect Closure at Very Young Age

An asymptomatic Atrial Septal Defect (ASD) is often closed at the age of 3–5 years using a transcatheter or surgical technique. Symptomatic ASD or ASD associated with pulmonary hypertension (PHT) may require earlier closure, particularly in combination with other non-cardiac risk factors for PHT, but the indications for early closure and the potential risk for complications are largely unknown. Th

Disability and Pain are the Best Predictors of Sick Leave After a Distal Radius Fracture in Men

Purpose Distal radius fracture often compromises working ability, but clinical implications are less studied in men due to its lower incidence. This study therefore describes sick leave in men with distal radius fracture, specifically exploring the impact of patient- and fracture-related factors. Methods Professionally active men aged 20–65 with distal radius fracture were followed prospectively f

Concussion incidence and recovery in Swedish elite soccer - prolonged recovery in female players

OBJECTIVES: Sport-related concussions are an increasingly recognized health problem. Soccer is the most popular sport in the world although recent studies on concussion incidence are scarce. Here, a nation-wide prospective study on concussion incidence, symptom severity, risk factors, gender differences and return-to-play after concussion was performed in 51 Swedish elite soccer teams during the 2

Mitotic Count and Estimation of the Risk of GIST Recurrence in Patients Treated with Preoperative Imatinib

Preoperative imatinib is used frequently in the treatment of large localized GISTs to shrink the tumor prior to surgery. This approach may lead to challenges in the estimation of the risk of recurrence and the need of adjuvant imatinib, because the diagnosis is usually made from a needle biopsy with scant tissue for the assessment of GIST mitotic activity, a key prognostic factor. We propose a mit

The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival : the Malmö Diet and Cancer Study

Background: Genetic factors are important in determining breast density, and heritable factors account for 60% of the variation. Certain single nucleotide polymorphisms (SNPs) are associated with density and risk of breast cancer but the association with prognosis is not clear. Purpose: To investigate associations between selected SNPs and breast cancer survival in the Malmö Diet and Cancer Study

Genetic screening of children with suspected inherited bleeding disorders

INTRODUCTION: Genetic screening using high-throughput DNA sequencing has become a tool in diagnosing patients with suspected inherited bleeding disorders (IBD). However, its usefulness and diagnostic efficacy in children is unclear.AIM: To evaluate the diagnostic efficacy of genetic screening for IBD in children and downstream further testing.METHODS: After informed consent, children (

Charitable organisations

This chapter focuses on the direct taxation issues arising vis-à-vis charities. Many charitable organizations are active in the EU. Because of their important role in civil society, they are often granted a special status in national tax legislation. The charity itself is not always the direct or statutory beneficiary of the tax incentives. However, the idea behind these incentives is that indirec

Crowd safety: prototyping for the future : Summary report showing how the science for “pedestrian flow” can keep up with demographic change

This report presents the final output from the project Crowd safety: prototyping for the future. The research includes a scoping study focusing on determining primary parameters for pedestrian movement and experimental results on movement in various conditions that focus on movement speed, contact distance and movement behaviour. A parametric model for predicting movement is presented based on thiThis report presents the final output from the project Crowd safety: prototyping for the future. The research includes a scoping study focusing on determining primary parameters for pedestrian movement and experimental results on movement in various conditions that focus on movement speed, contact distance and movement behaviour. A parametric model for predicting movement is presented based on thi

Lignocellulosic Ethanol in a Greenhouse Gas Emission Reduction Obligation System—A Case Study of Swedish Sawdust Based-Ethanol Production

A greenhouse gas (GHG) emission reduction obligation system has been implemented in the Swedish road transport sector to promote the use of biofuels. For transportation fuel suppliers to fulfil this obligation, the volume of biofuel required decreases with decreasing life cycle GHG emission for the biofuel, linking lower GHG emission to higher economic value. The aim of this study was to investiga

Non-negative least squares computation for in vivo myelin mapping using simulated multi-echo spin-echo T2 decay data

Multi‐compartment T2 mapping has gained particular relevance for the study of myelin water in the brain. As a facilitator of rapid saltatory axonal signal transmission, myelin is a cornerstone indicator of white matter development and function. Regularized non‐negative least squares fitting of multi‐echo T2 data has been widely employed for the computation of the myelin water fraction (MWF), and t

Impact of Spatially Consistent Channels on Digital Beamforming for Millimeter-Wave Systems: (Invited Paper)

The premise of massive multiple-input multiple-output (MIMO) is based around coherent transmission and detection. Majority of the vast literature on massive MIMO presents performance evaluations over simplified statistical propagation models. All such models are drop-based and do not ensure continuity of channel parameters. In this paper, we quantify the impact of spatially consistent (SC) models

SNAP - POP for Massive MIMO Systems

Massive multiple-input multiple-output (MIMO) has gained a tremendous amount of attention as a key enabler of fifth-generation cellular systems. The majority of the vast literature on massive MIMO is based on fully digital processing, where each antenna element in the massive array is equipped with an up/down-conversion chain. Unlike previous works, we present a suite of greedy algorithms using pu

Familial Risks of Heart Failure in Sweden

Hjärtsvikt betecknar ett syndrom som innebär att hjärtat har otillräcklig förmåga att försörja kroppen med blod. Detta kan antingen bero på att hjärtat inte kan fyllas med eller stöta ut tillräckligt med mängd blod. Patienter med hjärtsvikt har i allmänhet hög dödlighet, detta trots att stora framsteg har gjorts avseende behandlingen av hjärtsvikt, speciellt sedan 1980-talet. Femårsöverlevnaden föIntroduction: Despite major advances, the incidence rate and mortality of heart failure (HF) remains high, with a five-year survival of approximately 50%. At the time of inception of this thesis the familial risks of HF, including the aspects of mortality, were largely underdetermined. This thesis is composed of four papers with the main aims as follows:To determine the risk of hospitalization of