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Patients' initial steps to cancer diagnosis in Denmark, England and Sweden : what can a qualitative, cross-country comparison of narrative interviews tell us about potentially modifiable factors?

OBJECTIVES: To illuminate patterns observed in International Cancer Benchmarking Programme studies by extending understanding of the various influences on presentation and referral with cancer symptoms.DESIGN: Cross-country comparison of Denmark, England and Sweden with qualitative analysis of in-depth interview accounts of the prediagnostic process in lung or bowel cancer.PARTICIPANTS: 155 women

Upretia, a new caloplacoid lichen genus (Teloschistaceae, Lichen-Forming Ascomycota) from India

New genus Upretia S. Y. Kondr., A. Thell & J. S. Hur is characterized by partly pruinose, lobate to subsquamulose, olivaceous grey to brown thallus, small ascospores and narrowly bacilliform conidia. It belongs to the subfamily Caloplacoideae of the Teloschistaceae and includes the ‘Caloplaca’ amarkantakana clade. The new genus is closely related to Ioplaca Poelt according to phylogeny analysi

Huseby Klev and the Quest for Pioneer Subsistence Strategies : Diversification of a Maritime Lifestyle

The bone material from three archaeological occupation phases at Huseby Klev provides the best source of evidence currently available about the subsistence strategies of pioneer settlers in Northern Europe. The results from Huseby Klev indicate that the pioneer settlers initially relied heavily on marine mammals for their sustenance. This subsistence strategy changed during the second and third oc

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

Background: Cross-sectional genome-wide association studies have identified hundreds of loci associated with blood lipids and related cardiovascular traits, but few genetic association studies have focused on long-term changes in blood lipids. Methods: Participants from the GLACIER Study (Nmax = 3492) were genotyped with the MetaboChip array, from which 29 387 SNPs (single nucleotide polymorphisms

The biology of color

Coloration mediates the relationship between an organism and its environment in important ways, including social signaling, antipredator defenses, parasitic exploitation, thermoregulation, and protection from ultraviolet light, microbes, and abrasion. Methodological breakthroughs are accelerating knowledge of the processes underlying both the production of animal coloration and its perception, exp

Biofuels from agricultural biomass – Land use change in Swedish perspective

The Swedish parliament has decided that by 2045, Sweden will not be a net emitter of greenhouse gases. There is also a goal to have a fossil fuel free transport sector by 2030. However, the transport sector is still dominated by fossil fuels and many efforts are needed to lower emissions. Sweden has a relatively high share of biofuels, around 20% of the energy use in domestictransportation. Howeve

Attention and Learning through the Eyes of the Emotional Brain

The present thesis consists of four articles that address cognitive-emotional interactions as measured through eye movements and pupil dilation.Social facilitation-inhibition is an effect that describes changes in performance (enhancement or impairment) when individuals complete tasks in social presence compared to when they perform the same tasks in solitary conditions. Along this line, Paper I a

Outcome of percutaneous coronary intervention with the Absorb bioresorbable scaffold : Data from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)

Aims: Randomised trials indicate higher rates of stent thrombosis (ST) and target lesion failure (TLF) after percutaneous coronary intervention (PCI) with the Absorb bioresorbable scaffold (BRS) compared with modern drug-eluting stents (DES). We aimed to investigate the outcome of all Swedish patients treated with the Absorb BRS. Methods and results: The Absorb BRS (n=810) was compared with common

European Respiratory Society statement : Diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency

α1-antitrypsin deficiency (AATD) is the most common hereditary disorder in adults. It is associated with an increased risk of developing pulmonary emphysema and liver disease. The pulmonary emphysema in AATD is strongly linked to smoking, but even a proportion of never-smokers develop progressive lung disease. A large proportion of individuals affected remain undiagnosed and therefore without acce

Infiltration of γδ T cells, IL-17 + T cells and FoxP3 + T cells in human breast cancer

BACKGROUND: Tumor-infiltrating lymphocytes (TILs) have a strong prognostic value in various forms of cancers. These data often refer to use of the pan-T cell marker CD3, or the cytotoxic T lymphocyte marker CD8α. However, T cells are a heterogeneous group of cells with a wide array of effector mechanisms ranging from immunosuppression to cytotoxicity. OBJECTIVE: In this study we have investigated

High-resolution Monthly Satellite Precipitation Product over the Conterminous United States

We present a data set that enhanced the Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA) monthly product 3B43 in its accuracy and spatial resolution. For this, we developed a correction function to improve the accuracy of TRMM 3B43, spatial resolution of ~25 km, by estimating and removing the bias in the satellite data using a ground-based precipitation data

Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions

Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphis