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Interaction with the host : the role of fibronectin and extracellular matrix proteins in the adhesion of Gram-negative bacteria

The capacity of pathogenic microorganisms to adhere to host cells and avoid clearance by the host immune system is the initial and most decisive step leading to infections. Bacteria have developed different strategies to attach to diverse host surface structures. One important strategy is the adhesion to extracellular matrix (ECM) proteins (e.g., collagen, fibronectin, laminin) that are highly abu

Female sex, high soluble CD163, and low HDL-cholesterol were associated with high galectin-3 binding protein in type 1 diabetes

Background: Galectin-3 binding protein (Gal3BP), sCD163, galectin-3, and depression have been linked to cardiovascular disease and mortality. In patients with type 1 diabetes, female sex has also been linked to cardiovascular disease and mortality. The aim was to explore whether female sex, sCD163, galectin-3, and depression were associated with Gal3BP in patients with type 1 diabetes. We adjusted

Effect of nicotine 6 mg gum on urges to smoke, a randomized clinical trial

Background: Ability to manage urges to smoke is fundamental to maximizing the chances of success in smoking cessation. Previous studies have linked a higher dose of nicotine in nicotine replacement therapy to a higher success rate for smoking cessation. Thus, this study was performed to compare relief of urges to smoke, up until 5 h following treatment with a new 6 mg nicotine gum versus currently

Being the next of kin of an older person living in a nursing home : an interview study about quality of life

BACKGROUND: The length of stay in nursing homes before death in Sweden has significantly decreased, and nearly one-third of people die within 6 weeks of entering a nursing home. Support for the next of kin is one of the cornerstones of palliative care, but the principles are not always adhered to as recommended when caring for the elderly, which can affect the quality of life of their next of kin.

From Africa to Europe : evidence of transmission of a tropical Plasmodium lineage in Spanish populations of house sparrows

BACKGROUND: Avian malaria parasites are a highly diverse group that commonly infect birds and have deleterious effects on their hosts. Some parasite lineages are geographically widespread and infect many host species in many regions. Bird migration, natural dispersal, invasive species and human-mediated introductions into areas where competent insect vectors are present, are probably the main driv

Clinical significance of stromal ER and PR expression in periampullary adenocarcinoma

Background: Tamoxifen treatment has previously been reported to confer life-prolonging effects in patients with advanced pancreatic cancer, and most evidently so in women. None of these trials did however include biomarkers, and the relevance of female hormone signaling in pancreatic or other periampullary adenocarcinoma remains largely unexplored. The aim of this study was to examine the extent a

Comorbidities and sex differences in causes of death among mantle cell lymphoma patients – A nationwide population-based cohort study

The prognosis for mantle cell lymphoma (MCL) remains poor. Our aim was to assess the impact of comorbidities on survival and causes of death. For 1,385 MCL patients (1,009 males, 376 females) diagnosed in 2000–2014 (median age 71 years, range 22–96) comorbidities ≤ 10 years of diagnosis were classified according to the Charlson comorbidity index (CCI; 0, 1, 2+). Hazard ratios (HRs) with 95% confid

Twelve complete chloroplast genomes of wild peanuts : great genetic resources and a better understanding of Arachis phylogeny

BACKGROUND: The cultivated peanut (Arachis hypogaea) is one of the most important oilseed crops worldwide, however, its improvement is restricted by its narrow genetic base. The highly variable wild peanut species, especially within Sect. Arachis, may serve as a rich genetic source of favorable alleles to peanut improvement; Sect. Arachis is the biggest taxonomic section within genus Arachis and i

Förord

Detta är den nionde skriften i forskningsprogrammet Vetenskap och beprövad erfarenhets (VBE:s) skriftserie om begreppet vetenskap och beprövad erfarenhet. Denna gång är skriften resultatet av ett pågående samarbete med forskningsprogrammet Foresight vid Malmö universitet. Foresights forskning är inriktad på att hitta nya verktyg för att identifiera patienter som löper ökad risk för karies och tand

Saddle point approaches in strong field physics and generation of attosecond pulses

Attoscience is the emerging field that accesses the fastest electronic processes occurring at the atomic and molecular length scales with attosecond (1 as = 10−18 s) time resolution having wide ranging physical, chemical, material science and biological applications. The quintessential and one of the most fundamental processes in this domain is the generation of phase locked XUV attosecond pulses.

Factors regulating the coastal nutrient filter in the Baltic Sea

The coastal zone of the Baltic Sea is diverse with strong regional differences in the physico-chemical setting. This diversity is also reflected in the importance of different biogeochemical processes altering nutrient and organic matter fluxes on the passage from land to sea. This review investigates the most important processes for removal of nutrients and organic matter, and the factors that re

Optical theorems and physical bounds on absorption in lossy media

Two different versions of an optical theorem for a scattering body embedded inside a lossy background medium are derived in this paper. The corresponding fundamental upper bounds on absorption are then obtained in closed form by elementary optimization techniques. The first version is formulated in terms of polarization currents (or equivalent currents) inside the scatterer and generalizes previou

Fluorine Abundances in the Galactic Disk

The chemical evolution of fluorine is investigated in a sample of Milky Way red giant stars that span a significant range in metallicity from [Fe/H] ∼-1.3 to 0.0 dex. Fluorine abundances are derived from vibration-rotation lines of HF in high-resolution infrared spectra near 2.335 μm. The red giants are members of the thin and thick disk/halo, with two stars being likely members of the outer disk

Correlating the Bethesda System for Reporting Thyroid Cytopathology with Histology and Extent of Surgery : A Review of 21,746 Patients from Four Endocrine Surgery Registries Across Two Continents

Background: The Bethesda system for cytopathology (TBSRTC) is a 6-tier diagnostic framework developed to standardize thyroid cytopathology reporting. The aim of this study was to determine the risk of malignancy (ROM) for each Bethesda category. Methods: Thyroidectomy-related data from 314 facilities in 22 countries were entered into the following outcome registries: CESQIP (North America), Eurocr

Chemical Heterogeneity of Mg, Mn, Na, S, and Sr in Benthic Foraminiferal Calcite

The chemical composition of fossil foraminiferal shells (tests) is widely used as tracers for past ocean chemistry. It is, therefore, important to understand how different (trace) elements are transported and incorporated into these tests from adjacent seawater. The elemental distribution within the walls of foraminiferal tests might be used to differentiate between proposed transport mechanisms.

Effect of the addition of thermostable and non-thermostable type 2 resistant starch (RS2) in cake batters

There is interest in increasing the consumption of foods with high dietary fiber content due to the health problems associated with its low intake. Plantain (Musa paradisiaca L.) flour (PF) (non-thermostable) and Hi-Maize 260 (HA) (thermostable) were used as resistant starch (RS) sources to elaborate blends with wheat (WF) and rice flours (RF) in a 50:50 ratio. Five blends were prepared (PF-WF, PF

Comparison of Performance and Effectiveness of Vertical Borehole Heat Exchanger Collectors

The number of heating and cooling system using vertical borehole heat exchangers is increasingly rapidly in Sweden. Currently, there are over 600,000 installations, mostly using U-tube ground collectors. In recent years, several new ground collectors with innovative designs and configurations have been launched. They claim to have superior performance and competitive advantages over the convention

Modelling creep in a pre-stressed mock-up reactor containment : The VeRCoRs 2018 benchmark case

In this study, a multiphysics model is presented that predicts creep in three months old concrete cylinders subjected to drying. The model includes concrete hydration, and a moisture transport model with relative humidity as the driving potential. These parameters are important to include in order to simulate creep. The model was implemented in the finite element software COMSOL Multiphysics. The