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Background-The PR interval, as measured by the resting, standard 12-lead ECG, reflects the duration of atrial/atrioventricular nodal depolarization. Substantial evidence exists for a genetic contribution to PR, including genome-wide association studies that have identified common genetic variants at 9 loci influencing PR in populations of European and Asian descent. However, few studies have exami

Atherosclerotic cardiovascular disease (CVD) is a leading cause of mortality and morbidity worldwide, with coronary artery disease (CAD) being the single leading cause of death. Better control of risk factors, enhanced diagnostic techniques and improved medical therapies have all substantially decreased the mortality of CAD in developed countries. However, CAD and other forms of atherosclerotic CV

New fundamental particles, charged under new gauge groups and only weakly coupled to the standard sector, could exist at fairly low energy scales. In this article we study a selection of such models, where the secluded group either contains a softly broken U(1) or an unbroken SU(N). In the Abelian case new gamma(v) gauge bosons can be radiated off and decay back into visible particles. In the non-

Objective. The aim of this study was to evaluate enterocystometry, voiding pattern and urine leakage of four types of orthotopic bladder substitute. Material and methods. At eight urological departments, 78 consecutive men were studied: 66 with an ileal neobladder [30 Studer pouches (S), 24 Hautmann pouches (H) and 12 T-pouches (T)] and 12 with a right colonic [Goldwasser type (G)] neobladder. Ent

The two major forms of the amyloid-beta (Aβ) peptide found in plaques in patients suffering from Alzheimer's disease, Aβ40 and Aβ42, only differ by two amino acids in the C-terminal region, yet they display markedly different aggregation behavior. The origins of these differences have remained challenging to connect to specific molecular-level processes underlying the aggregation reaction. In this

Ischemic stroke induces migration of newly formed neuroblasts, generated by neural stem cells in the adult rat subventricular zone (SVZ), towards the injured striatum where they differentiate into mature neurons. Stroke also leads to accumulation of microglia in the SVZ but their role for neurogenesis is unclear. Here we developed a method for selective depletion of the macrophage antigen complex-

The field of cytometry has grown in scope and importance ever since the early 20th century with leaps in technology introducing the Coulter counter and the flow cytometer. Cytometry methods have brought about a revolution for the medical and biotechnology industry by providing fast and accurate analysis of cell and particle suspensions. Recent developments in the field aim at improving current cyt

Aim. This article is a report of a study of how healthcare professionals involved in surgery orientate themselves to their common task, and how this orientation can be affected by the social and organizational context. Background. Previous research indicates that surgical teams are not as cohesive as could be expected and that communication failures frequently occur. However, little is known abo

To evaluate late outcomes after fenestrated endovascular aortic repair (f-EVAR) in a tertiary European referral center.

The purpose of this study was to investigate whether Danish children from immigrant backgrounds are less physically active than children from the ethnic majority, and to investigate the possible reasons for any differences found. Accelerometer measures of physical activity as well as questionnaire data about organised sports, family demography, resources and values were collected from 594 children

Since pesticides are disputed risk factors for uveal melanoma, we studied the association between occupational pesticide exposure and uveal melanoma risk in a case-control study from nine European countries. Incident cases of uveal melanoma and population as well as hospital controls were included and frequency-matched by country, 5-year age groups and sex. Self-reported exposure was quantified wi

There are various transport phenomena (gas-phase species, heat, and momentum) occurring at different length scales in anode-supported solid oxide fuel cells (SOFCs), which are strongly affected by catalytic surface reactions at active triple-phase boundaries (TPBs) between the void space (for gas), Ni (catalysts for electrons), and YSZ (an electrolyte material for ions). To understand the multisca

The distributions of event-by-event harmonic flow coefficients v (n) for n = 2- 4 are measured in = 2.76 TeV Pb + Pb collisions using the ATLAS detector at the LHC. The measurements are performed using charged particles with transverse momentum p (T) > 0.5 GeV and in the pseudorapidity range |eta| < 2.5 in a dataset of approximately 7 mu b(-1) recorded in 2010. The shapes of the v (n) distribution

We present a measurement of the cross section and transverse single-spin asymmetry (AN) for. mesons at large pseudorapidity from root s = 200 GeV p up arrow + p collisions. The measured cross section for 0.5 < p(T) < 5.0 GeV/c and 3.0 < vertical bar eta vertical bar < 3.8 is well described by a next-to-leading-order perturbative-quantum-chromodynamics calculation. The asymmetries A(N) have been me

A broadened typology describing the interconnection between energy and security is developed in this paper, with the aim of improving understanding of the relationship between energy and security by applying different research and policy perspectives. One approach involves studying energy as an object exposed to security threats, using concepts such as security of supply or security of demand. Ano

The gas produced in a biomass gasifier contains high amounts of tars which have to be removed prior to downstream utilization. Calcined dolomite is catalytically active for tar cracking reactions and resistant to sulfur poisoning. In this study, calcined dolomite was used as bed material in a reverse-flow reactor for cracking of tars in a model synthesis gas. 1-methylnaphthalene was used as model

Pancreatic cancer is one of the most severe cancers and is predicted to rise up to the number two cancer killer by 2030. The ineffective treatment options available and that the cancer is silent until very late in its course are the main reasons for the poor outcome of the disease. Surgery is the only curative option but only available for 10-15 % of the patients, but even then many relapse due to

In this work, we present recent shell model calculations, based on a realistic nucleon-nucleon interaction, for the light Sn-107,Sn-109 nuclei. By combining the calculations with the semi-classical Coulomb excitation code GOSIA, a set of gamma-ray intensities has been generated. The calculated intensities are compared with the data from recent Coulomb excitation studies in inverse kinematics at th

Background: Women with germline BRCA1 or BRCA2 (BRCA1/BRCA2) mutations are at very high risk of developing breast cancer, including asynchronous contralateral breast cancer (CBC). BRCA1/BRCA2 genes help maintain genome stability and assist in DNA repair. We examined whether the risk of CBC associated with radiation treatment was higher among women with germline BRCA1/BRCA2 mutations than among non