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Inclusive fitness benefits have been suggested to be a major selective force behind the evolution of cooperative breeding. We investigated the fitness benefits selecting for cooperative breeding in the Seychelles warbler, Acroccphalus sechellensis. A microsatellite-based genotyping method was used to determine the relatedness of subordinates to group offspring in an isolated population of Seychell
Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.., trisomies ? are also frequent. Little is known about the biologic outcome, the pathogenetic significan
PURPOSE: We review the current epidemiological and genetic knowledge regarding hereditary prostate cancer, and outline its clinical implications. MATERIALS AND METHODS: Published articles on hereditary prostate cancer were identified using the MEDLINE data base. RESULTS: A risk of prostate cancer, particularly early onset disease, is strongly affected by family history (number of relatives with pr
Abstract is not available
Tec family protein tyrosine kinases have in their N-terminus two domains, The PH domain is followed by Tec homology (TH) domain, which consists of two motifs, The first pattern, Btk motif, is also present in some Pas GAP molecules, C-terminal half of the TH domain, a proline-rich region, has been shown to bind to SH3 domains, Mutations in Bruton's tyrosine kinase (Btk) belonging to the Tec family
Starting out from the rather different views on Ego and Alter formulated by Peirce and Bakhtin, and, more indirectly, by Foucault, the present contribution attempts to characterise the position of these familiar philosophical personages within the framework of cultural semiotics, as it has been adapted in Lund from the models of the Prague and Tartu schools. The resulting model is tried out in a c
Popular Abstract in Swedish C1q, en delkomponent av C1 molekylen, och mannan-bindande protein (MBL) är igenkänningsmolekyler i komplementsystemet. De har likartad struktur. C1q binder till IgG och IgM och aktiverar den klassiska vägen. MBL binder till kolhydratstrukturer och aktiverar lektinvägen. Autoantikroppar mot C1q förekommer ofta vid svår systemisk lupus erythematosus (SLE) och förekommer oThe C1 subcomponent C1q and the mannan-binding lectin (MBL) are recognition proteins of the complement system, and have similar structure. C1q binds to IgG and IgM and activates the classical pathway. MBL binds to carbohydrate structures and activates the lectin pathway. Autoantibodies to C1q are frequently found in severe systemic lupus erythematosus (SLE) and are present in virtually all patient
This dissertation deals with the process of contextualizing the Christian discourse with a specific focus on worship and power negotiation. The study is based on literature, interviews and approximately six months of fieldwork in the U.S. in the years 1996,1998, and 2004. I focus on negotiation of power in the light of increasing Christian encounter with different cultural contexts and changing pe
Translocations involving an immunoglobulin (IG) locus are a recurring theme in B cell neoplasia. The rearrangements lead to the joining of an IG gene with a (proto)oncogene, whereby the latter comes under the influence of transcription-stimulating sequences in the constitutively active IG locus resulting in deregulation of the oncogene and neoplastic growth. We present here three cases of B cell n
A cDNA encoding the mature human cysteine proteinase inhibitor cystatin C was fused to the coding sequence for the Escherichia coli outer membrane protein A signal peptide, and the recombinant gene was expressed in E. coli under the control of the λ PR promoter, an optimized Shine-Dalgarno sequence and the λ cI 857 repressor. When induced at 42°C, such cells expressed large amounts of recombinant
Consider a stationary normal process ξ(t) with mean zero and the covariance function r(t). Properties of the sample functions in the neighborhood of zeros, upcrossings of very high levels, etc. have been studied by, among others, Kac and Slepian, 1959 [4] and Slepian, 1962 [11]. In this paper we shall study the sample functions near local maxima of height u, especially as u → -∞, and mainly use si
1. Task-dependent modulation of cutaneous input to climbing fibres projecting to the C1, C2 and C3 zones in the cerebellar paravermal lobule V was investigated in awake cats during performance of a reaching task. 2. Climbing fibre responses resulting from low intensity (non-noxious) electrical stimulation of the ipsilateral superficial radial nerve were recorded as extracellular field potentials i
Generation of clusters of free eosinophil granules (Cfegs), through lysis of eosinophils, has recently been proposed as a major paradigm for ultimate activation of airway mucosal eosinophils. In the present study involving patients with seasonal allergic rhinitis, we have investigated whether generation of Cfegs in the nasal mucosa is a feature of allergic rhinitis. Nasal mucosal biopsies were obt
X-ray absorption spectroscopy (XAS) and scanning tunneling microscopy (STM) have been used to study the absorption of monolayers of the pyridinecarboxylic acid monomers (isonicotinic acid, nicotinic acid, and picolinic acid) and benzoic acid on a rutile TiO2(1 1 0) surface. We find that the pyridine and phenyl rings are oriented with their planes largely perpendicular to the surface. The azimuthal
