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Modeling Human Hematopoiesis Using the CRISPR/Cas9 System
Hematopoietic stem cells (HSCs) have the ability to self-renew and to give rise to all blood cells of the different lineages, and are thereby responsible for the replenishment of blood cells throughout life. These cells are tightly regulated by extrinsic and intrinsic regulators, such as signals from the bone marrow microenvironment, complex transcription factor networks and epigenetic regulators.
Tomas Bokedal. Frihet och förtvivlan : Sören Kierkegaard om gudsförhållandet och självets helande
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Sven-Erik Brodd & Gunnar Weman. Prästgårdsteologi : Församlingspräster under 1900-talets senare hälft utmanar 2000-talets kyrka
A cross-sectional study of anxiety and depression caseness in female competitive figure skaters in Sweden
Objectives Little is known about figure skaters’ mental health. This study aimed to describe anxiety and depression caseness (defined as a screening condition qualifying for psychiatric examination) in competitive figure skaters and analyse factors associated with such caseness.Methods A cross-sectional study was performed in April 2019 among all competitive figure skaters in the south-eastern reg
Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study
Background: Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive. Methods: We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the EPIC coh
Characterization Factors to Assess Land Use Impacts on Pollinator Abundance in Life Cycle Assessment
While wild pollinators play a key role in global food production, their assessment is currently missing from the most commonly used environmental impact assessment method, Life Cycle Assessment (LCA). This is mainly due to constraints in data availability and compatibility with LCA inventories. To target this gap, relative pollinator abundance estimates were obtained with the use of a Delphi asses
The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial : Study protocol for a randomised crossover trial
Background: Hypertension is the leading modifiable risk factor for cerebral small vessel diseases (SVDs). Yet, it is unknown whether antihypertensive drug classes differentially affect microvascular function in SVDs. Aims: To test whether amlodipine has a beneficial effect on microvascular function when compared to either losartan or atenolol, and whether losartan has a beneficial effect when comp
The Chirality-Flow Formalism for Standard Model Calculations
Scattering amplitudes are often split up into their color (su(N) ) and kinematic components. Since the su(N) gauge part can be described using flows of color, one may anticipate that the su(2 ) ⊕ su(2 ) kinematic part can be described in terms of flows of chirality. In two recent papers we showed that this is indeed the case, introducing the chirality-flow formalism for standard model calculations
Viking Spectrophotometer : A Home-Built, Simple, and Cost-Efficient Absorption and Fluorescence Spectrophotometer for Education in Chemistry
Investigating the optical properties of various chemical compounds using UV-vis spectrophotometers is an essential part of education in chemistry. However, commercial spectrophotometers are usually treated as "magic black boxes", where the dominant majority of optical elements are hidden "under the hood". This often limits understanding of the mechanisms behind the generation of spectral curves, w
Missed Evaporation from Atmospherically Relevant Inorganic Mixtures Confounds Experimental Aerosol Studies
Sea salt aerosol particles are highly abundant in the atmosphere and play important roles in the global radiative balance. After influence from continental air, they are typically composed of Na+, Cl-, NH4+, and SO42- and organics. Analogous particle systems are often studied in laboratory settings by atomizing and drying particles from a solution. Here, we present evidence that such laboratory st