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Frequency of Achilles Tendon Xanthoma in Patients with Acute Coronary Syndrome

AIM: We studied the frequency of Achilles tendon xanthoma (ATX) in patients with acute coronary syndrome (ACS). Furthermore, we investigated the differences in clinical findings between ACS patients with and without ATX.METHODS: Patients with ACS (n=335) were admitted to the coronary care unit of Nippon Medical School between July 2011 and December 2014. Informed consent for the measurement of Ach

A biokinetic and dosimetric model for ionic indium in humans

This paper reviews biokinetic data for ionic indium, and proposes a biokinetic model for systemic indium in adult humans. The development of parameter values focuses on human data and indium in the form of ionic indium(III), as indium chloride and indium arsenide. The model presented for systemic indium is defined by five different pools: plasma, bone marrow, liver, kidneys and other soft tissues.

Beyond Massive MIMO: The Potential of Positioning with Large Intelligent Surfaces

We consider the potential for positioning with a system where antenna arrays are deployed as a large intelligent surface (LIS), which is a newly proposed concept beyond massive multi-input multi-output (MIMO) where future man-made structures are electronically active with integrated electronics and wireless communication making the entire environment "intelligent". In a first step, we derive Fishe

Vitamin K: A potential Liver Cancer treatment way

A review on different vitamin K1-3 effects on hepatocellular cancer and their tumour cell biology mechanism indicate possible synergistic treatment strategies. Monitoring of dysfunctional carboxylation of the vitamin K dependent coagulation factor II, with the commercial ELISA test PIVKA-II has been used as a hepatocellular cancer marker. Its relevance is also reviewed. Currently the PIVKA-II test

Identification and characterization of candidate therapeutic targets in acute myeloid leukemia

Acute myeloid leukemia (AML) is a fatal disease that is characterized by a rapid expansion of myeloid leukemic blasts with impaired differentiation that accumulate in the bone marrow. The prognosis for AML is generally poor, with a five-year overall survival of around 20% in patients over 60 years old. Current AML treatment strategies, including chemotherapy and hemapoietic stem cell trasplantatio

High-Speed Broadband and Academic Achievement in Teenagers: Evidence from Sweden

This study examines the effects of super-fast internet connections on the academic achievement of students in upper secondary school. We link detailed register data on around 250,000 students to local levels of access to optic fiber broadband, in order to estimate a causal effect of broadband on student GPA. We show that reaching full coverage in the student’s parish of residence causes a GPA redu

Sovereignty and Bureaucracy in the Official Public Theories of the "Refugee Crisis" of 2015 in Sweden

In 2017, the Swedish government published an official report entitled "Att ta emot människor på flykt: Sverige hösten 2015." The report describes how Swedish state agencies, municipalities, and civil society conceptualized and managed the refugee crisis of 2015. This chapter spells out the official public theories expressed in this report and in doing so unfolds two key findings. First, the govern

α-cell glucokinase suppresses glucose-regulated glucagon secretion

Glucagon secretion by pancreatic α-cells is triggered by hypoglycemia and suppressed by high glucose levels; impaired suppression of glucagon secretion is a hallmark of both type 1 and type 2 diabetes. Here, we show that α-cell glucokinase (Gck) plays a role in the control of glucagon secretion. Using mice with α-cell-specific inactivation of Gck (αGckKO mice), we find that glucokinase is required

Continuing global improvement in human papillomavirus DNA genotyping services : The 2013 and 2014 HPV LabNet international proficiency studies

Background: Accurate and internationally comparable human papillomavirus (HPV) DNA detection and typing services are essential for HPV vaccine research and surveillance. Objectives: This study assessed the proficiency of different HPV typing services offered routinely in laboratories worldwide. Study design: The HPV Laboratory Network (LabNet) has designed international proficiency panels that can

Amyloid pathology in the progression to mild cognitive impairment

The objective of this study was to determine the cognitive and functional decline and development of brain injury in individuals progressing from preclinical (β-amyloid positive cognitively normal) to prodromal Alzheimer's disease (AD) (β-amyloid positive mild cognitive impairment [MCI]), and compare this with individuals who progress to MCI in the absence of significant amyloid pathology. Seventy

Double-Thinking and Contradictory Arrangements in Iranian Law and Society

Although thinking double thoughts and living dual lives are not specifically Iranian traits, Iranians have nevertheless become more susceptible to them for historical reasons, which may be traced back to when Persians became Muslims. The gradual normalization of double-thinking over the centuries has given rise to social and political patterns of behavior and institutional arrangements which oscilAlthough thinking double thoughts and living dual lives are not specifically Iranian traits, Iranians have, nevertheless, become more susceptible to them for historical reasons, which may be traced back to when Persians became Muslims. The gradual normalization of double‐thinking over the centuries has given rise to social and political patterns of behavior and institutional arrangements which osc

Iran: A Clash of Two Cultures?

Since the 1979 Revolution, the clerical regime in Iran has been limiting the legal profession’s autonomy by preventing members of the Iranian Bar Association (IBA) from freely electing their Board of Directors and by establishing a new body of lawyers—legal advisors of the judiciary—to contest the IBA’s professional monopoly. Clerics have even attempted to bring the legal profession under the contSince the 1979 Revolution, the clerical regime in Iran has been limiting the legal profession’s autonomy by preventing members of the Iranian Bar Association (IBA) from freely electing their Board of Directors and by establishing a new body of lawyers—legal advisors of the judiciary—to contest the IBA’s professional monopoly. Clerics have even attempted to bring the legal profession under the cont

Pain sensitivity and pericranial tenderness in children with tension-type headache: A controlled study

Purpose: To compare tenderness and pain sensitivity in children (aged 7–17 years) with tension-type headache (TTH) and healthy controls using total tenderness score (TTS), pressure pain threshold (PPT), and pain perceived at suprapressure pain threshold (supraPPT). Patients and methods: Twenty-three children with frequent episodic TTH, 36 with chronic TTH, and 57 healthy controls were included. TT