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Biphasic differential changes of GABAA receptor subunit mRNA levels in dentate gyrus granule cells following recurrent kindling-induced seizures
GABAA receptor alpha 1, beta 3 and gamma 2 subunit mRNA levels have been measured in hippocampus using in situ hybridization, following 1, 10 and 40 seizures produced by rapid kindling stimulations. Major alterations of gene expression were largely confined to the dentate gyrus. One stimulus-induced seizure reduced gamma 2 mRNA levels in the dentate gyrus by 30%. In contrast, mRNA expression incre
A Program for the Interactive Solution of Parametric Optimization Problems in Dynamic Systems
Exploring light-cone sum rules for pion and kaon form factors
We analyze the higher-twist effects and the SU(3)-flavor symmetry breaking in the correlation functions used to calculate form factors of pseudoscalar mesons in the QCD light-cone sum rule approach. It is shown that the Ward identities for these correlation functions yield relations between twist-4 two-and three-particle distribution amplitudes. In addition to the relations already obtained from t
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Are minor gene effects of clinical importance?
Adsorption of lithium on the Si(111)7 × 7 surface studied with high resolution core-level spectroscopy
Li-adsorption on the Si(111)7 × 7 surface at room temperature has been studied for different metal coverages with core-level spectroscopy. Four Li-induced components are observed in the Si 2p level at high Li-coverages indicating the formation of four thermodynamically stable phases. It is shown that the reaction between the Li atoms and the Si(111)7 × 7 surface takes place in two steps. In the fi
Quantification, of photosystem I and II in different parts of the thylakoid membrane from spinach
Abstract: Electron paramagnetic resonance (EPR) was used to quantify Photosystem I (PSI) and PSII in vesicles originating from a series of well-defined but different domains of the thylakoid membrane in spinach prepared by non-detergent techniques. Thylakoids from spinach were fragmented by sonication and separated by aqueous polymer two-phase partitioning into vesicles originating from grana and
Role of nuclear factor-kappaB, reactive oxygen species and cellular signaling in the early phase of acute pancreatitis.
Genetisk variation hos vilda växter och djur i Sverige
A 5-hydroxymethyl furfural reducing enzyme encoded by the Saccharomyces cerevisiae ADH6 gene conveys HMF tolerance
The fermentation of lignocellulose hydrolysates by Saccharomyces cerevisiae for fuel ethanol production is inhibited by 5-hydroxymethyl furfural (HMF), a furan derivative which is formed during the hydrolysis of lignocellulosic materials. The inhibition can be avoided if the yeast strain used in the fermentation has the ability to reduce HMF to 5-hydroxymethylfurfuryl alcohol. To enable the identi
XAFS experiments at beamline I811, MAX-lab synchrotron source, Sweden
A description of a new facility for X-ray absorption spectroscopy at the materials science beamline, I811, at MAX-lab synchrotron source, Lund, Sweden, is given. The beamline is based on a superconducting multipole wiggler source inserted in a straight section of the 1.5 GeV MAX-II ring. X-rays in the energy range 2.4- 12 keV are extracted by a standard optical scheme consisting of a vertical coll
Repliker (två) på Lars Gahrns och Mats G. Larssons angrepp på undertecknad
The interaction between the ISO tapping machine and lightweight floors
The ISO standard tapping machine, used as an excitation source in rating the impact-sound level of a floor structure, interacts with the floor structure during the hammer impact. Expressions for the force spectrum due to the impact are presented. The 6 dB difference at low frequencies of the force spectrum, evident in measurements, and reasons for it, are discussed. The interaction is investigated
Energi för att bygga bruka riva småhus, Bo92 : Den nya trästaden
I denna rapport redovisas energiberäkningar för tre småhus på Bo 92 i Örebro. Syftet med rapporten är att beräkna och analysera det totala energibehovet och mängd byggnadsmaterial från 'vaggan till graven' för småhus. Med det totala energibehovet menas summan av energibehovet under produktion (materialtillverkning, materialtransporter och uppförande av byggnaden), förvaltning (brukande av byggnade
First observation of vibrations in core-level photoelectron spectra of free neutral molecular clusters
Core-level photoelectron spectra of free neutral methane clusters have been recorded. These spectra exhibit well-resolved surface and bulk features as well as vibrational fine structure. The vibrational structure in the cluster signal is well reproduced by a theoretical model that assumes independent contributions from inter- and intramolecular modes. The intramolecular contribution to the vibrati
Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial-like ATP-sensitive K+ (KATP) conductance in rat pancreatic A-cells
1. Capacitance measurements were used to examine the effects of the sulphonylurea tolbutamide on Ca2+-dependent exocytosis in isolated glucagon-secreting rat pancreatic A-cells. 2. When applied extracellularly, tolbutamide stimulated depolarization-evoked exocytosis 4.2-fold without affecting the whole-cell Ca2+ current. The concentration dependence of the stimulatory action was determined by intr
Water dimer in solid neon. Far-infrared spectrum
Infrared spectra of water and deuterated water isolated in neon matrices have been recorded between 20 and 5000 cm(-1). The water concentration has been varied between very low concentrations with only monomers present up to concentrations where pentamers and possibly hexamers are present in significant amounts. The concentration dependencies of the observed absorption bands have been used to assi
INVASIVE BLADDER CANCER - Aspects on staging and prognosis
Background: The difficulty of determining the prognosis for the individual patient with invasive bladder cancer is a major clinical problem. Currently, decisions regarding therapy are mainly based on tumour stage and grade, the first of which is notoriously demanding to ascertain. New molecular markers are however proposed to be of prognostic value. At present, there is considerable debate regardi
Static and Dynamic Modelling of the Drying Section of a Paper Machine
Popular Abstract in Swedish Papperstillverkning inkluderar flera processteg såsom flisning av träråvaran, massakokning och avvattning med vakuumlådor, pressning och torkning. Flera modeller av de mest viktiga processerna i torkpartiet presenteras i denna avhandling. Modellerna beskriver både statiska och dynamiska förlopp. Nya reglerstrategier som kan användas för både reglering vid stationär drifThe paper making process involves chopping of wood, cooking and forming, followed by dewatering in a vacuum section, press section and drying section. Several models for the most important parts of the paper machine drying section are presented in this thesis to describe phenomena at steady state and during state transitions. New control strategies applicable/useful for both steady-state control a