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Correlation between Surface and Tumour Motion in Lung Cancer - including Deep Learning Perspectives

Av de 70 000 personerna som blev diagnoserade med cancer i Sverige 2021, fick runt 4000 lungcancer. Lungcancer är vanligen elakartade celler som utgår från lungans slemhinna. Behandling innefattar oftast operation eller strålterapi, ibland i kombination med cellgifter eller immunterapi. Inför strålbehandling gör patienten en röntgenundersökning som ger bilder i tre dimensioner, en så kallad datorPurpose: The purpose of this master thesis was to retrospectively investigate correlation between surface and tumour motion in lung cancer patients, alongside deep learning applications of the results. Additional correlations such as age, tumour volume and anatomical placement of the tumour were also investigated. Materials and Methods: 48 lung cancer patients treated with Stereotactic Body Radia

Morphology-Dependent Interactions between α-Synuclein Monomers and Fibrils

Amyloid fibrils may adopt different morphologies depending on the solution conditions and the protein sequence. Here, we show that two chemically identical but morphologically distinct α-synuclein fibrils can form under identical conditions. This was observed by nuclear magnetic resonance (NMR), circular dichroism (CD), and fluorescence spectroscopy, as well as by cryo-transmission electron micros

Optimization of High-order Harmonic Generation for Attosecond Science

High-order harmonic generation is a highly nonlinear, though inherently inefficient, process which can lead to emission of coherent, broadband extreme ultraviolet radiation in the form of attosecond pulses. Attosecond pulses are crucial for experiments investigating photoionization dynamics on the femto- and attosecond timescales. As attosecond research tends towards increasingly complex light-mat

After the Beginning, Before the End

An essay revisiting Stephen Andrews's series of works including drawings and video produced from unofficial sources following the United States invasion of Iraq in 2003.

Sounding Pico

Sounding Pico is an art project focussing on the Pico-neighbourhood in Santa Monica, CA in the USA –developed in collaboration between artist Maj Hasager and composer Ask Kæreby during winter 2018-19. In response to the often-mediated image of a troubled area with opportunities lost, rather than gained, countermeasures have been taken – perhaps most notably by the cultural asset database Culture M

Phylogeny of Holocacista capensis (Lepidoptera: Heliozelidae) from Vineyards and Natural Forests in South Africa Inferred from Mitochondrial and Nuclear Genes

In South Africa, the family Heliozelidae in the order Lepidoptera is restricted to four known species. The grapevine leaf miner, Holocacista capensis, feeds between the epidermal layers of a grapevine leaf, predominantly along the leaf margin. A final instar larva will descend from the blotch mine/gallery to attach its cocoon casing (constructed from the epidermal layers of the mined gallery) to a

A Potential Neuroprotective Role for Pyruvate Kinase 2 in Retinal Degeneration

Retinitis pigmentosa (RP) is an inherited disorder that results in vision impairment that specific therapeutic strategies are not available. However, it is widely regarded that the cGMP system, including cGMP and its interactor cGMP-dependent protein kinase (PKG), acts as a crucial effector during retinal degeneration. We have previously identified a list of cGMP-PKG-dependent genes in the context

The Covid-19 Lesson from Sweden: Don’t Lockdown

The coronavirus pandemic triggered strong political action across Europe. Mandatory restrictions to increase social distancing were imposed, commonly known as lockdowns. In some cases, entire countries were virtually locked down for several weeks at a time, contributing to a very severe downturn in economic activity. To mitigate the policy induced economic crisis, governments responded by introduc

Large Eddy Simulation of Ramjet to Scramjet Transition

The dual-mode ramjet engine is one of the most promising propulsion systems for hypersonic flight because it can be operated in a wide range of flight Mach numbers. This engine type will be quite complicated to use in practice since it requires Ma

MAJIANG

The cultural significance of a language is multifaceted and complex. Language exists as not just a means of communication, but also a reflection of the history, traditions, values, and beliefs of a culture. Language holds within it the stories, myths, and art, passed down through generations and contains the nuances and subtleties of a community’s way of life, including their customs, social norms

Oscillator Based Readout System For Inductively Coupled Stretchable Resistive Strain Sensor

The development and use of stretchable electronics is a relatively new research field. However, the use of these kinds of electronics could prove fruitful when seeking to improve medical sensors and equipment. Since the substrates and manufacturing methods used when making stretchable electronics allows them to be extremely thin, with a thickness in the μm range. At these thickness levels, the ele

Student engagement with digital video production

In many contexts of contemporary ELT, the L2 can be widely encountered beyond the classroom. In these settings, teachers need to maximize opportunities for meaningful participation. Digital video production (DVP) provides one such opportunity. Little, however, is known about the types of DVP common in particular contexts of ELT, the extent to which DVP functions as a motivational resource, or how

Rewarding foreign language learning : effects of the Swedish grade point average enhancement initiative on students' motivationto learn French.

In order to reinstate interest and motivation for learning foreign languages (FLs) other than English, the Swedish government has recently reformed the admissions system to higher education. Upper secondary students who continue with the FL learnt in secondary school are rewarded with extra credits that considerably enhance their grade point average (GPA). The purpose of this interview-based study

Examining the impact of L2 English on L3 Selves : A case study

In this Swedish case study of four upper secondary students engaged in simultaneous L2 (English) and L3 (Spanish, French and Russian) learning, a possible selves approach was used to investigate the impact of English on L3 motivation. Using a maximum variation sampling strategy, participants were selected from a larger dataset (n=101). Semi-structured interviews were conducted using Interpretive P

Biofilm formation on endovascular aneurysm repair (EVAR) grafts– a proof of concept in vitro model

ObjectivesAn endovascular aneurysm repair (EVAR) graft is a catheter-implanted vascular prosthesis and is the preferred treatment for patients with aortic aneurysm. If an EVAR graft becomes the focus of infection, the treatment possibilities are limited as it is technically difficult to remove the graft to obtain source control. This study examines whether Pseudomonas aeruginosa and Staphylococcus

Threats to validity in software engineering research: A critical reflection

Context: In the contemporary body of software engineering literature, some recurrent shortcomings characterize how threats to validity (TTV) are considered in studies. Objective: With this position paper, we aim to open a discourse on the current use of TTV sections. The goal of our position is to jointly reflect and systematically improve how we, as a research community, consider TTV in our studi

A Phenomenographic Analysis Of Students’ Experience Of Geological Time

Geological time is by many geoscience instructors considered a threshold concept for geoscience students, being a central concept for how we experience geosceince phenomena that takes place on a spatio-temporal scale ranging from micro (e.g. cloud formation) to macro (e.g. plate tectonics). If one wishes to understand geoscience phenomena that goes beyond human perception, one must move from the cGeological time is by many geoscience instructors considered a threshold concept for geoscience students, being acentral concept for how we experience geosceince phenomena that takes place on a spatio-temporal scale rangingfrom micro (e.g. cloud formation) to macro (e.g. plate tectonics). If one wishes to understand geoscience phenomenathat goes beyond human perception, one must move from the conc