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Systematic uncertainties in the determination of the local dark matter density

A precise determination of the local dark matter density and an accurate control over the corresponding uncertainties are of paramount importance for dark matter (DM) searches. Using very recent high-resolution numerical simulations of a Milky Way like object, we study the systematic uncertainties that affect the determination of the local dark matter density based on dynamical measurements in the

An alternative to grids and glasses : Quaquaversal pre-initial conditions for N-body simulations

N-body simulations sample their initial conditions on an initial particle distribution, which for cosmological simulations is usually a glass or grid, while a Poisson distribution is used for galaxy models, spherical collapse, etc. These pre-initial conditions have inherent correlations, noise due to discreteness, and preferential alignments, while the glass distribution is poorly defined and comp

Telomere length in children environmentally exposed to low-to-moderate levels of lead

Shorter relative telomere length in peripheral blood is a risk marker for some types of cancers and cardiovascular diseases. Several environmental hazards appear to shorten telomeres, and this shortening may predispose individuals to disease. The aim of the present cross-sectional study was to assess the effect of environmental exposure to lead on relative telomere length (rTL) in children. A coho

Discordant pattern of BRCA1 gene epimutation in blood between mothers and daughters

Methylation of the promoter of BRCA1 gene in peripheral blood (epimutation) has been associated with increased risk for breast cancer. Some studies have indicated that this epimutation is of constitutional origin and hence it could potentially be transmitted across generations. We used methylation sensitive high resolution melting technique to measure methylation of BRCA1 promoter in blood samples

A simplified approach to array optimization for the DC resistivity and induced polarization method

In this work a simplified approach to array optimization for the DC resistivity and induced polarization method have been created and tested. The optimization method uses the centre of the sensitivity function for the individual electrode configurations, called the mass centre, which is spread over the area of investigation, wherefrom the name Spread of Mass Centre (SMC). This array has been teste

A systematic look at the effects of radiative feedback on disc galaxy formation

Galaxy formation models and simulations rely on various feedback mechanisms to reproduce the observed baryonic scaling relations and galaxy morphologies. Although dwarf galaxy and giant elliptical properties can be explained using feedback from supernova and active galactic nuclei, Milky Way-sized galaxies still represent a challenge to current theories of galaxy formation. In this paper, we explo

A dark disc in the Milky Way

Predicting the flux of dark matter particles through the Earth is vital for current and future direct dark matter detection experiments. To date, such predictions have been based on simulations that model the dark matter alone. Here we make the first attempt to include the influence of the baryonic matter. We show that the presence of a stellar/gas disc at high redshift (z ∼ 1) causes merging sate

The Long-Term Economic Effects of Polio: Evidence from the Introduction of the Polio Vaccine to Sweden in 1957

This study explores the impact an exogenous improvement in childhood health has on later-life outcomes. Using extensive and detailed register data from the Swedish Interdisciplinary Panel, we follow individuals exposed to the introduction of the first vaccine against polio in Sweden (birth cohorts 1937-1966) until adulthood in order to quantify the causal effect of polio vaccination on long-term e

Surface Engineering of Quantum Dots for Remarkably High Detectivity Photodetectors.

Ternary alloyed CdSexTe1–x colloidal QDs trap-passivated by iodide-based ligands (TBAI) are developed as building blocks for UV–NIR photodetectors. Both the few surface traps and high loading of QDs are obtained by in situ ligand exchange with TBAI. The device is sensitive to a broad wavelength range covering the UV–NIR region (300–850 nm), showing an excellent photoresponsivity of 53 mA/W, a fast

Anomalies, VMD and the Extended NJL model

We show how the effective action of the Extended Nambu-Jona-Lasinio model (ENJL) can be defined in the presence of anomalies in a way that reproduces the flavour anomaly. This necessarily breaks Vector Meson Dominance (VMD) in the usual sense. The same method can be used to construct other chiral effective theories involving constituent quarks and spin-1 mesons that give the correct flavour anomal

The role of von Willebrand factor in acute type A aortic dissection and aortic surgery

Introduction: Massive bleeding is a serious complication associated with impaired survival after surgery for acute type A aortic dissection (ATAAD). There are no previous reports evaluating the effect of ATAAD and associated surgery on von Willebrand factor (VWF). The aim of the present study was to analyze VWF activity (VWF:GPIbM) and thus the potential of Factor (F) VIII/VWF concentrate as a tre

Electromagnetic contributions to vector meson masses and mixings

We use the 1/Nc method to estimate electromagnetic contributions to vector meson masses and mixings. We identify several new sources of ρ - ω mixing coming from short-distance effects. We comment on the extraction of quark masses from the vector meson masses. We also present a simple group theoretical discussion of the electromagnetic mass differences.

Status of Fragmentation Models

Phenomenological models of multiparticle production have become increasingly important for the interpretation of experimental data in high energy physics. The evolution of these models fills a gap left open by the present limited theoretical understanding of the hadronization process, i.e. the transformation of outgoing colored partons into color singlet hadrons. The three main schools of thought,

Refinement of protein structures using a combination of quantum-mechanical calculations with neutron and X-ray crystallographic data

Neutron crystallography is a powerful method to determine the positions of H atoms in macromolecular structures. However, it is sometimes hard to judge what would constitute a chemically reasonable model, and the geometry of H atoms depends more on the surroundings (for example the formation of hydrogen bonds) than heavy atoms, so that the empirical geometry information for the H atoms used to sup