We perform wavefront measurements of high-order harmonics using an extreme-ultraviolet (XUV) Hartmann sensor and study how their spatial properties vary with different generation parameters, such as pressure in the nonlinear medium, fundamental pulse energy and duration as well as beam size. In some conditions, excellent wavefront quality (up to 휆/11) was obtained. The high throughput of the inten

Purpose: To evaluate the impact of multiple potential sociodemographic and clinical stroke-related determinants on self-perceived manual ability in an unselected sample of individuals 12 months after first-ever stroke. Methods: A cross-sectional sample of 68 participants (mean age 66) with UE impairments were followed up at 12 months post stroke. Stroke severity at onset was moderate for the major

We introduce the Assembling Galaxies Of Resolved Anatomy (AGORA) project, a comprehensive numerical study of well-resolved galaxies within the ΛCDM cosmology. Cosmological hydrodynamic simulations with force resolutions of 100 proper pc or better will be run with a variety of code platforms to follow the hierarchical growth, star formation history, morphological transformation, and the cycle of ba

The effects of particle discreteness in N-body ACDM simulations are still an intensively debated issue. In this paper we explore such effects, taking into account the scatter caused by the randomness of the initial conditions and focusing on the statistical properties of the cosmological density field. For this purpose, we run large sets of ACDM simulations and analyze them using a wide variety of

We have previously reported recurrent clonal chromosomal aberrations in synovia, osteophytes and articular cartilage from patients with osteoarthritis (OA). In particular, gain of chromosomes 5 and 7 was found to be strongly associated with OA. In order to exclude the possibility of in vitro artefacts, we studied three to four parallel, independent cultures from ten samples of synovia and three sa

Background: The proportion of adults with liver disease due to severe alpha-1-antitrypsin deficiency (AATD), with PiZZ phenotype, is not clear. The markers of the AATD liver disease, how it progresses, and measures for its prevention have not been established. The aim of this study was to analyze the risk of liver disease in individuals with severe AAT deficiency (PiZZ). Methods: Longitudinal clin

Objective: Routine antibiotic treatment of acute uncomplicated diverticulitis (AUD) has been shown ineffective. In this study, the adherence to a new treatment protocol for uncomplicated diverticulitis was evaluated and the incidence of complications in patients treated with and without antibiotics was investigated. Materials and methods: A retrospective study of in-patients diagnosed with AUD at

We study a capacitated network design problem in a geometric setting. The input consists of an integral edge capacity k and two sets of points on the Euclidean plane, sources, and sinks, with an integral demand for each point. The demand of each source specifies the amount of flow that has to be shipped from the source, and the demand of each sink specifies the amount of flow that has to be shippe

Pulmonary artery grafts are needed as cardiovascular bioprosthetics. For successful tissue recellularization after transplantation, lipids have to be removed from the donor artery. Developing a selective process to remove lipids without damaging the extracellular matrix greatly depends on knowing the amount and type of lipid compounds in the specific tissue. Here we present an efficient methodolog

Climate change will bring about a consistent increase in temperatures. Annual precipitation rates are also expected to increase in boreal countries, but the seasonal distribution will be uneven, and several areas in the boreal zone will experience wetter winters and drier summers. This study uses the dynamic forest ecosystem model ForSAFE to estimate the combined effect of changes in temperature a

Aim: This nonsystematic review examined differences in the composition of raw maternal breastmilk and pasteurised donor milk and possible health effects on preterm infants. Methods: We searched PubMed up to July 2018 for studies published in English that focused on four comparisons as follows: raw maternal milk versus donor milk, human milk before and after Holder pasteurisation, milk from mothers

We fit the rotation curves of isolated dwarf galaxies to directly measure the stellar mass-halo mass relation (M*-M200) over the mass range 5 × 105 ≲ M*/M⊙ ≲ 108. By accounting for cusp-core transformations due to stellar feedback, we find a monotonic relation with little scatter. Such monotonicity implies that abundance matching should yield a similar M*- M200 if the cosmological model is correct

Observations of turbulent velocity dispersions in the H i component of galactic discs show a characteristic floor in galaxies with low star formation rates and within individual galaxies the dispersion profiles decline with radius. We carry out several high-resolution adaptive mesh simulations of gaseous discs embedded within dark matter haloes to explore the roles of cooling, star formation, feed

We study the formation of disc galaxies in a fully cosmological framework using adaptive mesh refinement simulations. We perform an extensive parameter study of the main subgrid processes that control how gas is converted into stars and the coupled effect of supernovae feedback. We argue that previous attempts to form disc galaxies have been unsuccessful because of the universal adoption of strong

A straightforward synthesis of anti-3-alkenyl-2-amido-3-hydroxy esters from the corresponding racemic α-amino-β-keto esters by using a ATH/DKR protocol has been developed. This method gives moderate to excellent yields with high chemo-, diastereo- and enantioselectivities for a broad range of substrates. In order to highlight the versatility of the methodology it was applied in an efficient asymme

This paper aims at developing a benchmark simulation model to evaluate control strategies for the urban catchment and sewer network. Various modules describing wastewater generation in the catchment, its subsequent transport and storage in the sewer system are presented. Global/local overflow based evaluation criteria describing the cumulative and acute effects are presented. Simulation results sh

BACKGROUND: The aim of this study was to investigate the possibility of using extended-wavelength diffuse reflectance spectroscopy (EW-DRS) to measure tissue response related to blood perfusion. The study was performed on a model that we have previously found to be useful for studying techniques for perfusion monitoring following the injection of epinephrine in a local anesthetic in the human fore