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A linear mixed perfusion model for tissue partial volume correction of perfusion estimates in dynamic susceptibility contrast MRI: : Impact on absolute quantification, repeatability, and agreement with pseudo-continuous arterial spin labeling

PURPOSE: The partial volume effect (PVE) is an important source of bias in brain perfusion measurements. The impact of tissue PVEs in perfusion measurements with dynamic susceptibility contrast MRI (DSC-MRI) has not yet been well established. The purpose of this study was to suggest a partial volume correction (PVC) approach for DSC-MRI and to study how PVC affects DSC-MRI perfusion results.METHOD

Dynamic susceptibility contrast perfusion MRI using phase-based venous output functions: : comparison with pseudo-continuous arterial spin labelling and assessment of contrast agent concentration in large veins.

OBJECTIVES: Contrast agent (CA) relaxivities are generally not well established in vivo, and the relationship between frequency/phase shift and magnetic susceptibility might be a useful alternative for CA quantification.MATERIALS AND METHODS: Twenty volunteers (25-84 years old) were investigated using test-retest pre-bolus dynamic susceptibility-contrast (DSC) magnetic resonance imaging (MRI). The

Tomosynthesis of the thoracic spine : added value in diagnosing vertebral fractures in the elderly

Objectives: Thoracic spine radiography becomes more difficult with age. Tomosynthesis is a low-dose tomographic extension of radiography which may facilitate thoracic spine evaluation. This study assessed the added value of tomosynthesis in imaging of the thoracic spine in the elderly. Methods: Four observers compared the image quality of 50 consecutive thoracic spine radiography and tomosynthesis