Development of a robust automated platform for enrichment of extracellular vesicles from low sample volume that matches the needs for next-generation sequencing could remove major hurdles for genomic biomarker discovery. Here, we document a protocol for urinary EVs enrichment by utilizing an automated microfluidic system, termed acoustic trap, followed by next-generation sequencing of microRNAs (m

The presence of the information age has greatly influenced how learning in higher education has evolved. Information Systems (IS) curricula are particularly liable with this trend and their likelihood to remain effective depends on how they orchestrate the use of technology. In this study, we evaluate an IS program that was designed and implemented in 2010. We assess its effectiveness eight years

Purpose: The purpose of this paper is to investigate the profitability of urban chicken production in the medium-sized cities of Kisumu and Thika, Kenya. Design/methodology/approach: Data were collected in 2016 from a sample of 157 indigenous chicken producers in the two cities. Descriptive analyses were used to characterize indigenous chicken production, marketing and profitability. In addition,

What Christian worship is all about has been discussed and expressed in many contexts: in dogmatic pronouncements, in ecumenical documents and declarations, in the writings of individual theologians. This article is a simple attempt to summarize the essence of some of the more influential of those writings. In order to make it as basic and as uncontroversial as possible I have based it on Bible pa

Reflection on the widely shared pattern or shape for the principal acts of Christian worship – on what has been called ordo – offers us several important gifts. It enables and supports a renewed accent on the central matters of that worship, the matters that N. F. S. Grundtvig called “bath, word, prayer, and table,” that Luther called “signs of life” and “marks of the church,” and that both Luther

BackgroundVasovagal reflex is the most common form of syncope, but the pathophysiological mechanisms that initiate the reflex are not well understood. We aimed to study supine and early orthostatic levels of the neurohormones involved in control of circulatory homeostasis in relation to the onset of tilt‐induced vasovagal syncope (VVS).Methods and ResultsA total of 827 patients who were investigat

In this chapter we ask if mass tourism, morphing into over-tourism, can be conceptualised as an emerging plague of zombie tourists, and what kinds of tourism futures might come of it? Overtourism is not only unsustainable; it is the logical outcome of capitalism and thus, a token signifying that the capitalist system is well and alive even though it is threatening everything else on Earth. We outl

Purpose: The purpose of this paper is to investigate how grocery retailers configure their online fulfilment centres (OFC) as they move towards an omni-channel structure and what contextual factors influence their decisions. Design/methodology/approach: An exploratory case study with three grocery retailers in the Nordic countries was conducted. The study investigates the current OFC configuration

Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is associated with a pro-inflammatory gene signature. Here, we investigate if the loss of Maf transcription factors induced autoimmune processes in the pancreas. Transcriptomics analysis showed expression of pro-inflammatory as well as immune cell