Idiopathic pulmonary fibrosis (IPF) is a fatal disease that exhibits patterns of usual interstitial pneumonia with honeycombing. IPF is characterized by damaged distal lung epithelium with excessive tissue scarring and extracellular matrix remodeling. The etiology of IPF is unknown and current therapies cannot end or reverse disease progression. Aberrant reactivation of developmental pathways is e

The aim of this study was to investigate how social workers in social service at child welfare experience and describe their work situation regarding workload and how they handle it when the workload is perceived as high. Individual qualitative semi-structured interviews were conducted with eight social workers who work with child welfare services. The empirical material that was obtained from the

Den här studien syftar till att undersöka och analysera hur genomförandet av övervakningsåtgärderna drogtestning, kameraövervakning och geopositioner kan resultera i en konflikt mellan arbetsrätten och GDPR. För att uppnå syftet kommer frågeställningar att besvara vilka rättsliga befogenheter arbetsgivaren har att genomföra kontrollåtgärder, hur GDPR begränsar genomförandet av kontrollåtgärder samThe purpose of the study is to analyze how employment law interact with GDPR when implementing the following monitoring actions of; drug test, camera surveillance and geopositioning at the workplace. This was investigated with three research questions looking at what right the employer has to implement monitoring actions, how GDPR limits the implementation of monitoring actions, and what contradic

Blood biomarkers indicative of Alzheimer’s disease (AD) pathology are altered in both preclinical and symptomatic stages of the disease. Distinctive biomarkers may be optimal for the identification of AD pathology or monitoring of disease progression. Blood biomarkers that correlate with changes in cognition and atrophy during the course of the disease could be used in clinical trials to identify

Importance: Meningioma is the most common subsequent neoplasm following cranial irradiation among survivors of childhood cancer, but there are still uncertainties regarding the magnitude of the radiation dose-response association, potential modifiers of radiation risks, and the role of chemotherapy. Objective: To evaluate meningioma risk in survivors of childhood cancer following radiotherapy and

Background: Influenza vaccination early after myocardial infarction (MI) improves prognosis but vaccine effectiveness may differ dependent on type of MI. Methods: A total of 2,571 participants were prospectively enrolled in the Influenza vaccination after myocardial infarction (IAMI) trial and randomly assigned to receive in-hospital inactivated influenza vaccine or saline placebo. The trial was c

Den statliga lönegarantin är en skyddslagstiftning som ger arbetstagare rätt till ersättning om arbetsgivaren går i konkurs. I en granskande rapport från Riksrevisionen framkommer det att 6–9 % av utbetalt garantibelopp utgörs av misstänkt missbruk av lönegarantin. Uppsatsens syfte är att undersöka om de föreslagna åtgärderna i Riksrevisionens granskning kan förväntas minska missbruk av lönegarantThe earnings guarantee is a legislation designated to compensate employees for loss of salary if the employer is declared bankrupt. In an audit by the Swedish National Audit Organization (the Swedish NAO), it is estimated that 6–9 % of all earnings guarantee payments consist of misusage. The purpose of this article is to examine if the measures suggested by the Swedish NAO can be considered adequa

Background: Over the past decade, several PET tracers were developed to visualise and quantify tau pathology in vivo. However, all these tracers have distinct off-target binding, different dynamic ranges and likely different levels of non-specific binding resulting in large variability in semiquantification. We propose to standardise the sampling and the quantification across all available tau tra

Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associate

This interview with Professor Irving Kirsch took place in late August, 2022. He recently turned 80 years old and agreed to focus his interview on topics and areas that illustrate his influence on the field of hypnosis. Professor Kirsch discusses the influences that shaped him as a person and scientist; what unites his theoretical and research work on hypnosis, placebo, and antidepressants. He also

A simultaneous measurement of the three components of the top-quark and top-antiquark polarisation vectors in t-channel single-top-quark production is presented. This analysis is based on data from proton–proton collisions at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 139 fb−1, collected with the ATLAS detector at the LHC. Selected events contain exactly one iso

In this Letter, we explore the use of thermodynamic length to improve the performance of experimental protocols. In particular, we implement Landauer erasure on a driven electron level in a semiconductor quantum dot, and compare the standard protocol in which the energy is increased linearly in time with the one coming from geometric optimization. The latter is obtained by choosing a suitable metr

Introduces a special issue on the development of the class action regime, in light of the reforms reflected in the Supreme Court decisions in Mastercard Inc v Merricks and Google LLC v Lloyd, and a conference hosted by the Bonavero Institute of Human Rights at the University of Oxford entitled "Access to Justice and Class Actions in England and Wales".

Context. Observations of the phase curves and secondary eclipses of extrasolar planets provide a window onto the composition and thermal structure of the planetary atmospheres. For example, the photometric observations of secondary eclipses lead to the measurement of the planetary geometric albedo, Ag, which is an indicator of the presence of clouds in the atmosphere. Aims. In this work, we aim to

Den ökade användningen av artificiell intelligens på e-handelsplattformar på-verkar hur konsumenter interagerar med varumärken i en onlinemiljö. Re-kommendationssystem samlar in information om användaren och presenterar därefter förslag på produkter som den tror användaren kommer finna intres-santa. Utöver en ökad närvaro av artificiell intelligens säljs alltmer förfalskade varor i takt med att onThe increased use of artificial intelligence at e-commerce platforms affects how consumers interacts with trademarks online. Recommendation systems is gathering data from the users and suggests products that it think the user will like. In addition to the increased use of artificial intelligence, the sales of coun-terfeited products are on the rise because of the increased e-commerce. E-commerce p