Heating of 1'-(N-substituted carbamoyl)methylspiro[2H-1-benzopyran-2,2'-[2H]indoles] with potassium hydroxide in ethanol yields diastereomeric 5a,13-methano-6H-1,3-benzoxazepino[3,2-a]indole-12-carboxamides. Reduction of the latter with sodium borohydride affords 1,2,3,9a-tetrahydro-2-hydroxyaryl-9H-pyrrolo[1,2-a]indole-3-carboxamides .

Omorganisationer i form av marknadsorienterade beställar-utförarmodeller och effektivisering har sedan början av 1990-talet fått mycket stor omfattning inom offentlig sektor. De startade utan några vetenskapliga stöd för att de nya formerna skulle resultera i bättre kvalitet i tjänsterna. Resultat från en tioårig empirisk studie inom hemtjänsten pekar i stort på ingen eller negativ inverkan på arb

We report on "safe" Coulomb excitation of neutron-rich (138,140,142) Xe nuclei. The radioactive nuclei have been produced by ISOLDE at CERN and post-accelerated by the REX-ISOLDE facility. The gamma-rays emitted by the decay of excited states have been detected by the MINIBALL array. Recent results are presented.

The inception of the sheet flow regime as well as the effects of the phase lag when the sheet flow regime is established were investigated for oscillatory flows and combined steady and oscillatory flows. A new criterion for the inception of sheet flow is proposed based on around 300 oscillatory flow cases from experiments. This criterion was introduced in the Camenen and Larson [Camenen, B., Larso

The blood group ABO gene shows considerable polymorphism in most of the 7 exons. Introns examined so far have also shown blood group-related polymorphisms, as has an upstream enhancer region. Several polymorphisms affect the specificity of the gene product (glycosyltransferase) and explain the occurrence of blood group A and B. Various lethal mutations result in blood group O. Other mutations are

Popular Abstract in Swedish S:t Germer och s:t Josse var två helgon som levde i norra Frankrike på 600-talet. Deras liv nedtecknades ganska kort tid efter deras död i tre olika versioner av författare som skrev på latin. I början av 1200-talet sammanställde Pierre de Beauvais detta material till två diktverk på franska, skrivna på åttastavig vers, 874 respektive 820 versar. Avhandlingen är en kritThe Life of Saint Germer and the Life of Saint Josse are two poems consisting of 874 and 820 octosyllabic verses respectively. They were written in the beginning of the 13th century by Pierre de Beauvais. The two poems are preserved in one manuscript only, the Grand recueil la Clayette, Paris, Bibl. nat. Nouv. acq. fr. 13521, written in the latter half of the 13th century by a scribe who was from

A section of the Vitabdck Clays at Eriksdal in southern Sweden was sampled for vertebrate fossils. Large bulk samples were collected from three horizons, including two coquina beds, VC3 and VC11, and a silty clay bed, VC7. Shark teeth are very common and constitute the main portion of the vertebrate material discussed herein. The selachian tooth faunas are almost exclusively represented by hybodon

Nodularin (Nod), produced by the brackish/marine cyanobacterium Nodularia spumigena, is a potent hepatotoxin, tumor promoter and is possibly carcinogenic to mammals. It is structurally and toxicologically related to the microcystins, produced by Microcystis aeruginosa in fresh water. A better understanding of the kinetics of Nod production might provide an insight into the physiological and ecolog

Thin trabeculae were dissected from the right ventricle of guinea-pig heart and stimulated to contract isometrically at 0.5 Hz (26 degrees C). Rapid and transient changes of force were obtained by inducing three extra systoles (ES1-3) at 450-ms intervals. The two regular contractions (P1-2) following (ES1-3) were potentiated. Fura-2 salt was microinjected into the preparation to monitor intracellu

Photophysical studies of pseudo-p-distyryl[2.2]paracyclophane, a model molecule of a stilbene dimer arranged in a brick-wall geometry, in tetrahydrofurane solution indicate the existence of at least two conformers in the ground state. The conformer A with the smallest optical gap of 3 eV has a short radiative lifetime of 3.3 ns, while the conformer B with an optical gap about 0.3 eV larger is much

Objectives. To study the combined effects of a low birth weight and a pronounced weight increase up to early adulthood on the presence of cardiovascular risk factors constituting the metabolic syndrome in late middle age. Design and setting. A structured sample of 396 men, 58 years old from the general population. Birth weight and weight at 18 years were obtained from medical records and registers

Popular Abstract in Swedish Att packa ryggsäcken och resa till tropikerna, till vad man ofta kallar ‘tredje världen’ för en längre tids vistelse anses ofta vara av avsevärd betydelse för en individs identitet och framtida liv. För många resenärer upplevs resan som ett sätt att ta kontroll över den egna tiden och rörelsen, en kontroll som betraktas som en bristvara i de miljöer resenärerna kommer fThis work addresses the phenomenon of long-term, so-called ‘independent’ travelling, or backpacking, often to destinations described as the ‘third world’. It regards backpacker journeys as arenas for identity work, for expressing individuality and a ‘strong character’. Rather than merely being a parenthetic detour in time and space a backpacker’s trip to the tropics can be understood as a creative

The possibility of using pervaporation for the recovery of natural aroma compounds in the food industry has been widely recognised. The aim of this study was to build a bridge between experimental studies of multi-component systems and potential applications of pervaporation in the food industry. Therefore, a novel process simulation of pervaporation has been developed for multi-component mixtures

Lying athwart both the temperate and subtropical zones, the Ning-Zhen Mountains are particularly prone to extreme floods in the summer months when cold fronts collide with the subtropics-derived warm airmasses. The Holocene flood deposits in the region may provide a long-term perspective on hydrographical change and its palaeoclimatic implications. Radiocarbon dates on carbonised wood preserved in