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Structural insights into the inhibition of cellobiohydrolase Cel7A by xylo-oligosaccharides

The filamentous fungus Hypocreajecorina (anamorph of Trichodermareesei) is the predominant source of enzymes for industrial saccharification of lignocellulose biomass. The major enzyme, cellobiohydrolase Cel7A, constitutes nearly half of the total protein in the secretome. The performance of such enzymes is susceptible to inhibition by compounds liberated by physico-chemical pre-treatment if the b

Measurement of the azimuthal correlation between the most forward jet and the scattered positron in deep-inelastic scattering at HERA

Deep-inelastic positron-proton scattering events at low photon virtuality, Q(2), with a forward jet, produced at small angles with respect to the proton beam, are measured with the H1 detector at HERA. A subsample of events with an additional jet in the central region is also studied. For both samples, differential cross sections and normalised distributions are measured as a function of the azimu

Rätten som rum, kropp och kontext - Det konceptuella förtingligandets rättsvetenskapliga relevans

Genom att beskriva rättens beroende av kontext och rumsliga och kroppsliga relationer i termer av förtingligande uttrycker jag i denna artikel en kognitionsvetenskaplig inriktning och relevans för ett bredare rättsvetenskapligt perspektiv på rättslig analys. Jag visar därmed, inte minst genom en rad exempel, på de begreppsliga lånens oundviklighet för rättsliga abstraktioner. Vi har ett behov av a

Sum rules and constraints on passive systems - a general approach and applications to electromagnetic scattering

Physical processes are often modeled as input-output systems. Many such systems obey passivity, which means that power is dissipated in the process. This thesis deals with the inevitable constraints imposed on physical systems due to passivity. A general approach to derive sum rules and physical limitations on passive systems is presented. The sum rules relate the dynamical behaviour of a system

Subpicosecond hard x-ray streak camera using single-photon counting.

We have developed and characterized a hard x-ray accumulating streak camera that achieves subpicosecond time resolution by using single-photon counting. A high repetition rate of 2 kHz was achieved by use of a readout camera with built-in image processing capabilities. The effects of sweep jitter were removed by using a UV timing reference. The use of single-photon counting allows the camera to re

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I denna artikel tar jag upp ett berättargrepp, den narrativa syllepsen, som inte fått någon större uppmärksamhet i litteraturteorin hittills. Den narrativa syllepsen definierades först av den franske litteraturteoretikern Gérard Genette år 1972 som ett berättargrepp där olika temporaliteter smälter samman. Begreppet har dock inte använts i någon större utsträckning därefter, vilket jag anser vara In this article I discuss a narrative device, the narrative syllepsis, which has not received much attention in literary theory until now. The narrative syllepsis was first defined by French literary theorist Gérard Genette as a narrative device where different temporalities merge. The concept has however not been used att a larger scale after Genette, something I find surprising taking into consi

Search for events with large missing transverse momentum, jets, and at least two tau leptons in 7 TeV proton-proton collision data with the ATLAS detector ATLAS Collaboration

A search for events with large missing transverse momentum, jets, and at least two tau leptons has been performed using 2 fb(-1) of proton-proton collision data at root s = 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. No excess above the Standard Model background expectation is observed and a 95% CL upper limit on the visible cross section for new phenomena is set, where th

Changes in cerebrospinal fluid and blood plasma levels of IGF-II and its binding proteins in Alzheimer's disease: an observational study.

The Insulin-like Growth Factor (IGF)-related system is implicated in neuroregeneration and cell repair, as well as regulating lifespan. IGF-II, one component of this system, has also been found to affect memory functions in a rat model. In this study we explored changes in the IGF-related system in patients with Alzheimer's disease (AD), including changes in IGF-II levels.

Konfessionell krigsmakt. Predikan och bön i den svenska armén 1611-1721

The broad aim of this thesis is to explain the fundamental themes and function of Swedish field sermons and field prayers, and so to re-examine the view in earlier research that field sermons were primarily ‘Old Testamentary’ in nature. Inspired by more recent international research, I hold that the sermons’ basic functions were twofold: discipline and comfort. What matters, is to understand the d

Safety Work with an Ethnic Slant

Ethnic discrimination in the criminal justice system is a well-researched topic, but the significance of ethnicity in policing activities at more mundane levels has attracted less attention. This article analyzes ethnographic data on municipal ‘safety work’ in a Swedish city troubled with robberies, vandalism, and violence. It shows how the efforts of different safety workers, operating to curb cr

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Leptin is an adipocyte-secreted hormone, the circulating levels of which correlate closely with overall adiposity. Although rare mutations in the leptin (LEP) gene are well known to cause leptin deficiency and severe obesity, no common loci regulating circulating leptin levels have been uncovered. Therefore, we performed a genome-wide association study (GWAS) of circulating leptin levels from 32,1

Multi-agent source seeking via discrete-time extremum seeking control

Recent developments in extremum seeking theory have established a general framework for the methodology, although the specific implementations, particularly in the context of multi-agent systems, have not been demonstrated. In this work, a group of sensor-enabled vehicles is used in the context of the extremum seeking problem using both local and global optimisation algorithms to locate the extrem

On Stern-Gerlach coincidence measurements and their application to Bell's theorem

We analyze a coincidence Stem-Gerlach measurement often discussed in connection with the derivation and illustration of Bell's theorem. The treatment is based on our recent analysis of the original Stern-Gerlach experiment [H. Wennerstrom and P.-O. Westlund, Phys. Chem. Chem. Phys. 14, 1677 (2012)1, where it is concluded that it is necessary to include a spin relaxation process to account for the

Ability of risk scores to predict a low complication risk in patients admitted for suspected acute coronary syndrome.

Background When acute coronary syndrome (ACS) cannot be ruled out, emergency department (ED) patients with chest pain are admitted for in-hospital observation because of the risk of complications such as arrhythmia and acute heart failure. A study was undertaken to compare the ability of three risk prediction models to identify patients at a very low risk of complications. Methods 559 consecutive