Background: The global incidence of stroke is on the rise, primarily due to an increase in the aging population and the prevalence of vascular risk factors among the elderly. However, stroke is a treatable condition if promptly recognized and managed effectively. To optimize stroke management, it is crucial to establish a well-prepared infrastructure comprising adequately trained physicians workin

Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory joint disease that affects all aspects of life. Rheumatology care strives to achieve optimal health based on person-centred care (PCC). Effective treatment is available, but patients still experience unmet needs.Aims: The overall aim of this thesis was to explore patients' perspectives of PCC and preferred outcomes in early RA. Specifi

Concerns about age-related biases in Artificial Intelligence (AI)’s design, development, and data generation raise alarms for potential social inequalities. AI art-generators like MidJourney, known for creating distinctive and artistic images, have gained attention recently. However, the critical examination of their potential biases remains limited. Our study aims to investigate age-related bias

Background: Adult males in Sweden exhibit an increased risk of cancer associated with an increased absorbed dose to the colon from the Chernobyl accident. Methods: A closed cohort, with information on hunter status, included all individuals living in northern Sweden in 1986. Complete annual information on exposure to 137Cs at the dwelling coordinate was available for a total of 2,104,101 individua

A computational method is proposed to calculate bound and resonant states by solving the Klein–Gordon and Dirac equations for real and complex energies, respectively. The method is an extension of a non-relativistic one, where the potential is represented in a Coulomb–Sturmian basis. This basis facilitates the exact analytic evaluation of the Coulomb Green’s operator in terms of a continued fracti

In recent years, there have been notable advancements in the ability to programme human cell identity, enabling us to design and manipulate cell function in a Petri dish. However, current protocols for generating target cell types often lack efficiency and precision, resulting in engineered cells that do not fully replicate the desired identity or functional output. This applies to different metho

BACKGROUND: Research indicates that among the risks associated with young people's alcohol and illicit drug use are sexual risks. However, insights into co-occurrence of substance use and sexual risks in adolescent samples and possible differences across countries are limited. METHODS: A sample of 1449 adolescents from Belgium, Sweden, the Czech Republic, and Germany screened positive for risky al

INTRODUCTION: Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 (Gal-3), a microglial activation regulator, holds promise as a therapeutic target and potential biomarker. Our study aimed to investigate Gal-3 levels in patients with FTD and assess its diagnostic potential. METHODS: We examined Gal-3 levels in brain, serum, and cerebrospinal flu

Enhancers are short DNA segments (50–1500 bp) that effectively activate gene transcription when transcription factors (TFs) are present. There is a correlation between the genetic differences in enhancers and numerous human disorders including cancer and inflammatory bowel disease. In computational biology, the accurate categorization of enhancers can yield important information for drug discovery

Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for characterizing LV hypertrophy. Subjects having undergone CMR were studied (cardiac patients, n = 2543; healthy volunteers, n = 100). A new measure, global wal

This study investigates how representatives from the Swedish Social Service and the Sweden City missions describe their responsibility concerning long-term housing for families in structural homelessness. The aim is also to have the representatives’ perspectives on how the situation for the target group can be improved. Even though the research concerning structural homelessness is well examined,

One of the most common cancers in women Ovarian cancer is a major health issue and a leading cause of cancer-related deaths among women globally. A key factor in progression of ovarian cancer is a process called glycosylation, where sugars are added to proteins, altering their function. This process involves an enzyme named FUT8, which is crucial for adding specific sugar molecules to proteins. I

Aim: To compare total metabolic tumour volume (tMTV), calculated using two artificial intelligence (AI)-based tools, with manual segmentation by specialists as the reference. Methods: Forty-eight consecutive Hodgkin lymphoma (HL) patients staged with [18F] fluorodeoxyglucose positron emission tomography/computed tomography were included. The median age was 35 years (range: 7–75), 46% female. The t

Industry 4.0, with its focus on flexibility and customizability, is pushing in the direction of wireless communication in future smart factories, in particular massive multiple-input multiple-output (MIMO), and its future evolution Large Intelligent Surfaces (LIS), which provide more reliable channel quality than previous technologies. As such, there arises the need to perform efficient scheduling

I Ekonomisk Debatt nummer 5 2023 publicerade vi en artikel där vi studeradeorsakerna bakom kronförsvagningen mot euron (Andersson och Jonung2023). Eftersom kronan tappat i värde över en längre tid valde vi ett långsiktigt perspektiv. Här utgick vi från Cassels köpkraftsparitetsteori och visadeatt svenska priser och nominella löner stigit snabbare än i euroområdet. Kronförsvagningen är ett resultat