Atherosclerotic plaques are characterized by an accumulation and subsequent oxidation of LDL, resulting in adaptive immune responses against formed or exposed neoepitopes of the LDL particle. Autoantibodies against native p210, the 3136–3155 amino acid sequence of the LDL protein apolipoprotein B-100 (apoB100) are common in humans and have been associated with less severe atherosclerosis and decre

Methotrexate (MTX) impairs antibody response after pneumococcal vaccination. We aimed to investigate differences in phenotypes of circulating B and T cells after pneumococcal conjugate vaccine (PCV) in rheumatoid arthritis (RA) patients on MTX (MTX group), RA without disease-modifying drugs (0DMARD), and controls (HC). MTX group (n = 11), 0DMARD (n = 12) and HC (n = 13) were studied. Blood samples

This report presents the results of sediment sampling in Rönne å (river) at Ängelholm, located in the north-western part of Scania, which is the southern-most province in Sweden. The sampling and subsequent grain-size analysis were performed primarily to verify hypotheses about main mechanisms controlling local scour at a number of sites where scour holes had been observed in the river during deta

In its most recent Energy Union package, the European Union puts citizens at the core of the cleanenergy transitions. Beyond policy, disruptive innovations in energy sectors are challenging thetraditional business model of large energy utilities. One such disruptive, social innovation is theemergence of new clean energy communities (“NEWCOMERS”).The possible benefits of these “NEWCOMERS” for their

The strength of Sen’s concept of poverty lies in the fact that it goes beyond the traditional concepts of poverty and is able to grasp the complexity of poverty. At the same time, the strength of Sen’s concept of poverty is also its weakness. It is very abstract indeed. Income does not tell us much about poverty according to the capability deprivation approach since poverty is more than being shor

Dimethyl sulfide (DMS) is produced by plankton in oceans and constitutes the largest natural emission of sulfur to the atmosphere. In this work, we examine new particle formation from the primary pathway of oxidation of gas-phase DMS by OH radicals. We particularly focus on particle growth and mass yield as studied experimentally under dry conditions using the atmospheric simulation chamber AURA.

Transnational police readily use martial language in the stories they tell about their work. Their actual work, however, tells a different and less dramatic story. Why, then, do they insist on these warlike tales? Why is there a discrepancy between the self-representation of transnational policing and its reality? Using an ethnographic study, this article provides some answers. First, it includes

Aim: Depression is common and rising in adolescents. Recent meta-analyses indicate a moderate effect of exercise on depression symptoms. Clinically referred adolescents and their experiences of an exercise intervention have rarely been studied. The aim of this study was to describe clinically referred adolescents’ experience of moderate to vigorous exercise as a treatment for depression. Methods:

Aerosol technology is a promising platform to synthesize and study core-shellnanoparticles - a multi-elemental nanoparticle system where the core of one material is covered by a shell of another material. In this thesis, two distinctly separate strategies have been explored to synthesize core-shell nanoparticles by aerosol methods: physical vapor deposition (PVD) by evaporation, and surface segreg

Cell fate reprogramming towards pluripotency or alternative somatic cell-types has highlighted the plasticity of adult somatic cells, providing new technologies to generate desired cell types for tissue repair or for disease modeling. There is momentum to bring these concepts to immunology by specifying unique immune cellular identities that set in motion immune responses. Dendritic cells (DCs) ar

MP2RAGE has become popular for T1 mapping at 7T. Accuracy is yet improved by using a separately acquired flip angle map when creating the protocol-specific lookup table. Here, two additional volumes acquired at differing flip angles are added to an MP2RAGE sequence to obtain two separate states of driven equilibriums, effectively forming a dual flip angle protocol within the cycle. By estimating t

Fitting the inversion recovery (IR) at multiple TI provides T1 estimates of high accuracy if performed in a single slice with full relaxation. We present anisotropic 3D variant based on MP-RAGE, where a T1-weighted driven equilibrium is prepared prior to inversion by a second RAGE readout. This abolishes the need for long recovery times and provides volumes of similar contrast for co-registration.

This study aims to theoretically advance the current context-oriented tradition in crisis communication by highlighting the political and technological contexts to understand organizational crises. Using China as a case, this study proposes a broader research agenda that expands the focus from individual, organizational, and cultural domains to political and technological domains for investigating

Controlling the saturation of bound magnetization in variable flip angle (VFA) experiments improves the derived parameter maps. Instead of using special CSMT RF pulses, we kept the rmsB1 constant simply by increasing the RF pulse duration with the square of the flip angle. At 3T, VFA T1 mapping of human brain thus showed better compliance to the Ernst equation than at constant pulse duration or B1

Inhomogenous Magnetization Transfer (ihMT), the differential response to irradiation at single and dual frequency offsets, is sensitive to myelination. Quantification of ihMT in terms of MT saturation (MTsat), the percent reduction of Mz, corrects for underlying T1 and B1+ and allows comparing different implementations to optimize multi-parameter mapping (MPM) protocols. ihMTsat in white matter is