Fetal immobilization affects skeletal development and can lead to severe malformations. Still, how mechanical load affects embryonic bone formation is not fully elucidated. This study combines mechanobiology, image analysis and developmental biology, to investigate the structural effects of muscular loading on embryonic long bones. We present a novel approach involving a semi-automatic workflow, t

Daylight availability for buildings has been an integral part of architecture since ancient times, yet for the vast majority of countries, criteria for daylight provision were not normative until the 20th century. This article examines the case of Sweden, where the term “daylight” first appeared in regulations in 1960, and assesses the daylight compliance of multi-dwelling buildings before and aft

BACKGROUND: Malignant mesothelioma (MM) is a therapy-resistant tumor, often causing an effusion. Drugs targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway have shown promising results, but assessment of PD-L1 expression to select patients for therapy has mainly been performed on histologic tissue samples. In a previous study, we showed that MM effusions are

Three-dimensional growth of nanostructures can be used to reduce the threading dislocation density that degrades III-nitride laser performance. Here, nanowire-based hexagonal GaN microprisms with flat top and bottom c-facets are embedded between two dielectric distributed Bragg reflectors to create dislocation-free vertical optical cavities. The cavities are electron beam pumped, and the quality (

Background: Controlled release (CR) systems have emerged as powerful platforms for innovative formulations and dietary designs to enhance the techno-functional performance of bioactive food ingredients both in human body and food products. Generally, the term CR, has developed to indicate delivery systems with optimal control over release rate and performance. However, there are principles and req

Vem bestämmer när det är läggdags? Titeln på Glenn Möllergrenskapitel anspelar på den anpassning som gäller för många äldre hemtjänstmottagare. Möllergren går igenom kommunala riktlinjer förhemtjänst och konstaterar att nästan alla handlar om ”basala behov”medan sådant som deltagande i politik, kultur, idrott och föreningsliv,som är en självklarhet för många av oss, tycks hamna utanför det somingå

Jordan has one of the lowest available water supplies in the world; meanwhile, Jordan has seen a large increase in population and refugee’s fluxes, leading to an increase in water demand. To address this unprecedented water scarcity, Jordan’s water must be used where its social and economic value is highest. Jordan must treat and reuse virtually every drop of water. With using brackish water (i.e,