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The present article explores meaning in relation to musical learning. One starting point is the assumption that a meaningful music education is strongly related to the social domain of music-making. The aim of this article is to provide analytical tools to understand how meaning is negotiated within instrumental music tuition. Our interest lies in formal higher music education, an arena where the

This interview with Professor Irving Kirsch took place in late August, 2022. He recently turned 80 years old and agreed to focus his interview on topics and areas that illustrate his influence on the field of hypnosis. Professor Kirsch discusses the influences that shaped him as a person and scientist; what unites his theoretical and research work on hypnosis, placebo, and antidepressants. He also

Intrinsic polarization-sensitive photodetectors (IPPDs) have attracted considerable attention in recent years due to their simplicity in configuration, making them ideal candidates for compact and integrated polarization-sensitive sensing and imaging systems. Photoactive films with intrinsic optical anisotropy are necessary for IPPDs. This study reports an achievement of photoactive films based on

The central thesis of this article is that the evolution of teaching is one of the main factors that lead to increasingly complex communicative systems in the hominin species. Following earlier analyses of the evolution of teaching, the following steps are identified: (i) evaluative feedback, (ii) drawing attention, (iii) demonstration and pantomime, (iv) communicating concepts, (v) explaining rel

Upper bounds on the focusing efficiency of aperture fields and lens systems are formulated using integral equation representations of Maxwell’s equations and Lagrangian duality. Two forms of focusing efficiency are considered based on lens exit plane fields and optimal polarization currents within lens design regions of prescribed shape and available materials. Bounds are compared against the perf

Impaired semen quality is present in approximately 50% of all infertile couples, indicating decreased fertility in the male. The etiology is unknown in 40-60% of the cases and standard semen parameters provide limited information about the cause and the chance for pregnancy in vivo or in vitro. Assessment of sperm DNA strand breaks may therefore be useful for optimal infertility treatment. Since t

Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery. Results: To expand our understanding of the underlying biological pathways and m

In this work, we consider the case of a strongly coupled dark/hidden sector, which extends the Standard Model (SM) by adding an additional non-Abelian gauge group. These extensions generally contain matter fields, much like the SM quarks, and gauge fields similar to the SM gluons. We focus on the exploration of such sectors where the dark particles are produced at the LHC through a portal and unde

A simultaneous measurement of the three components of the top-quark and top-antiquark polarisation vectors in t-channel single-top-quark production is presented. This analysis is based on data from proton–proton collisions at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 139 fb−1, collected with the ATLAS detector at the LHC. Selected events contain exactly one iso

Traditionally well developed in many countries around the world, occupational therapy targeting older people delivers qualified programmes for preventive home visits, community-based rehabilitation, fall prevention, lifestyle redesign, assistive technology provision, etc. Research findings are to an increasing extent being transferred to practice contexts and serve to successively strengthen the q

Mitigation option are not yet being implemented at the scale required to limit global warming to well below 2°C. Various factors have been identified that inhibit the implementation of specific mitigation options. Yet, an integrated assessment of key barriers and enablers is lacking. Here we present a comprehensive framework to assess which factors inhibit and enable the implementation of mitigati

The Cherenkov Telescope Array (CTA) will be the next-generation observatory in the field of very-high-energy (20 GeV to 300 TeV) gamma-ray astroparticle physics. Classically, data analysis in the field maximizes sensitivity by applying quality cuts on the data acquired. These cuts, optimized using Monte Carlo simulations, select higher quality events from the initial dataset. Subsequent steps of t

An enhanced flamelet generated manifold (FGM) model for large eddy simulation (LES) of turbulent spray combustion is presented. In the enhanced FGM model, a transported probability density function (TPDF) description of the FGM variables is employed. The TPDF is represented using the Eulerian stochastic fields (ESF) approach, and the method is applied to LES of spray combustion under conditions re

Chronic lymphocytic leukemia (CLL) is preceded by monoclonal B-cell lymphocytosis (MBL), a CLL precursor state with a prevalence of up to 12% in aged individuals; however, the duration of MBL and the mechanisms of its evolution to CLL remain largely unknown. In this study, we sequenced the B-cell receptor (BcR) immunoglobulin heavy chain (IGH) gene repertoire of 124 patients with CLL and 118 match

Cool flame has an important impact on the performance and emission of advanced low-temperature combustion (LTC) internal combustion engines (ICEs) in which the liquid fuel is injected earlier at a lower ambient temperature (Tam) than that in the conventional diesel combustion engines. However, the cool flame characteristics of spray combustion under ICEs conditions are not fully understood, e.g.,

The inorganic platinum complexes currently in clinical use for cancer treatment have severe side effects, and complexes with fewer side effects are required. One option is to use complexes that are inactive until they are light-activated. Theoretical chemistry can contribute to the design of these complexes, but most current theoretical methods lack explicit treatment of relativistic effects (sinc