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The intonation of wh- and yes/no-questions in Tokyo Japanese
The paper reports experimental results on the intonation of wh- and yes/no-questions in Tokyo Japanese, and discusses several implications for the semantic and phonological theories of focus. The intonation of declarative sentences, wh-questions, and yes/no-questions are systematically compared. The results show that the wh-question exhibits an F0-prominence on the wh-phrase, while the yes/no-ques
Filmstjärnorna som aldrig dör
Feature om hur digitalt skapade eller reproducerade skådespelare har fått en allt större roll i filmindustrin under senare år.
Mörka hemligheter i nya Sherlock
Krönika om tv-serien Sherlock.
Hardy hård historisk hjälte
Krönika om tv-serien Taboo.
Piraternas sista strid
Krönika om tv-serien Black Sails.
Mor är rar... och kannibal
Krönika om tv-serien Santa Clarita Diet.
Stem cells and fetal therapy: is it a reality?
Toxic effects of human and rodent variants of alpha-synuclein in vivo
In Parkinson's disease, abnormal alpha-synuclein (asyn) accumulation leads to the formation of soluble oligomeric species thought to be toxic to cells as well as intraneuronal inclusions. To date, the precise mechanisms leading to aggregation of asyn in the brain is not well-understood. Previous studies in yeast, drosophila, and transgenic mice suggested that a non-A beta component depleted versio
Application of a dynamic gastrointestinal in vitro model combined with a rat model to predict the digestive fate of barley dietary fibre and evaluate potential impact on hindgut fermentation
Processing affects the composition, structure and physico-chemical characteristics of dietary fibres, and further changes can occur along the gastro-intestinal tract before entering the colon where undigested carbohydrates may serve as a substrate for the microbiota. To elucidate the effects of dietary fibre characteristic and the impact of processing on the digestive fate of dietary fibre compone
The influence of incommensurability on the long-range periodicity of the Pd(100)-(5×5)R27°-PdO(101)
The structural model of the (5×5)R27°-PdO(101) surface oxide grown on Pd(100) has been proposed and refined by a number of authors over more than a decade. In the current contribution we discuss the long-range periodicity of this structure arising along one of the crystallographic directions due to its incommensurability with the substrate. Analyzing the results of surface sensitive diffraction st
Photoperiod- and temperature-mediated control of phenology in trees – a molecular perspective
(Table presented.). Summary: Trees growing in boreal and temperate regions synchronize their growth with seasonal climatic changes in adaptive responses that are essential for their survival. These trees cease growth before the winter and establish a dormant state during which growth cessation is maintained by repression of responses to growth-promotive signals. Reactivation of growth in the sprin
Våld i barnavårdsutredningar: Om socialtjänstens ansvar och viljan att veta
A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis
Studies have shown a causal link between high-calorie diet (HCD) and colon cancer. However, molecular mechanisms are not fully elucidated. To understand etiology of HCD-induced colon carcinogenesis, we screened 10 pathways linked to elevated colonic cell proliferation and chronic inflammation in an HCD-consuming human-relevant pig model. We observed elevated colonic mucosal interleukin-6 (IL-6) ex
Mass selection in laser-plasma ion accelerator on nanostructured surfaces
When an intense laser pulse interacts with a solid surface, ions get accelerated in the laser-plasma due to the formation of transient longitudinal electric field along the target normal direction. However, the acceleration is not mass-selective. The possibility of manipulating such ion acceleration scheme to enhance the energy of one ionic species (either proton or carbon) selectively over the ot
The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL)
Although significant improvements have been made in the treatment of acute lymphoblastic leukemia (ALL), there is a substantial subset of high-risk T-cell ALL (T-ALL) patients with relatively poor prognosis. Like in other leukemia types, alterations of the PI3K/mTOR pathway are predominant in ALL which is also responsible for treatment failure and relapse. In this study, we show that relapsed T-AL
Troponin T levels associated with genetic variants in NOTCH2 and MTNR1B in women with psychosis
Psychosis patients have increased prevalence of metabolic disorders, which increase the risk for cardiovascular disease. Elevated troponin T level is an early biomarker of cardiovascular damage. We tested for association between troponin T levels and genetic risk variants of elevated blood glucose level in psychosis. Glucose and troponin T levels correlated positively. MTNR1B rs10830963 and NOTCH2
THESES db : The algae 18S rDNA sequence-structure database for inferring phylogenies
The use of 18S rDNA sequences for inferring phylogenies, in particular for higher taxonomic level analysis, has a long tradition in phycology. Similar to ITS2, the 18S rDNA displays a conserved secondary structure that could be used simultaneously with the primary sequence to increase the amount of information used when inferring phylogenetic relationships. Sequence-structure phylogenetics is alre
Fast iterative retrieval algorithm for ultrashort pulse characterization using dispersion scans
We present an iterative retrieval algorithm based on data constraint for ultrashort pulse characterization using dispersion scan (d-scan). The proposed algorithm is much faster and leads to a drastic reduction of retrieval times, but, compared to the standard algorithm, it performs less robustly in the retrieval of noisy d-scan traces. The algorithm is tested on several simulated cases and in two
Study of ignition and extinction of small-scale fires in experiments with an emulating gas burner
The objective of this study is to explore mechanisms for ignition and extinction for condensed-phase fuels via the use of a gas-fueled burner. Flames were generated with a porous 25 mm circular burner using mixtures of methane and propane with nitrogen. The procedure was to specify a set of mass fluxes of nitrogen-fuel mixture that corresponded to the flash- fire- and extinction points and for the
