Sökresultat
Filtrera
Filtyp
Din sökning på "*" gav 529876 sökträffar
The Cost-effectiveness of Treating Diabetic Lower Extremity Ulcers with Becaplermin (Regranex): A Core Model with an Application Using Swedish Cost Data.
Optimisation and robustness analysis of a hydrophobic interaction chromatography step
Nutrition and aberrant DNA methylation patterns in atherosclerosis: More than just hyperhomocysteinemia?
Methylation is a reversible modification of DNA participating in epigenetic regulation of gene expression. It is now clear that atherosclerosis is associated with aberrant DNA methylation patterns in the vascular tissue and peripheral blood cells, but the origin of this anomaly is poorly understood. Based on evidence that global DNA hypomethylation coexists with hyperhomocysteinemia in advanced hu
Imprinted polymers - Tailor-made mimics of antibodies and receptors
The technique of molecular imprinting allows the formation of specific recognition sites in synthetic polymers through the use of templates or imprint molecules. These recognition sites mimic the binding sites of antibodies and other biological receptor molecules. Molecularly imprinted polymers can therefore be used in applications relying on specific molecular binding events. The stability, ease
Natural killer T-cell populations in C57BL/6 and NK1.1 congenic BALB.NK mice-a novel thymic subset defined in BALB.NK mice.
Natural killer (NK) T lymphocytes are a subpopulation of T lymphocytes regarded as early regulators of immune responses. The majority of NKT cells are restricted by the CD1d molecule. NKT cells have mostly been studied in one single mouse strain, C57BL/6 (B6), because of the absence of NK1.1 in other common mouse strains, and the lack of other reliable surface markers for CD1d-restricted cells. To
A clinically relevant contact allergy to methyldibromo glutaronitrile at 1% (0.32 mg/cm) detected by a patch test.
Paediatric day care surgery increased parental participation reduces costs
In this paper, the marginal or incremental consequences of increased parental participation in a day-care surgery unit are analysed. Information about the parental role and instruction concer treatment caused parents to assume a greater share of their child's postoperative care. This advantages for the involved participants. Children and their parents spent a shorter time at the attributable to nu
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling
Mutations in the CYLD gene cause tumors of hair-follicle keratinocytes. The CYLD gene encodes a deubiquitinase that removes lysine 63-linked ubiquitin chains from TRAF2 and inhibits p65/p50 NF-kappaB activation. Here we show that mice lacking Cyld are highly susceptible to chemically induced skin tumors. Cyld-/- tumors and keratinocytes treated with 12-O-tetradecanoylphorbol-13 acetate (TPA) or UV
The impact of routine outcome measurement on treatment processes in community mental health care – approach and methods of the MECCA study
Three issues characterise the background to the MECCA study: A) Throughout Europe, most patients with severe forms of psychotic disorders are cared for in the community. The challenge now is to make processes in community mental health care more effective. B) There are widespread calls to implement regular outcome measurement in routine settings. This, however, is more likely to happen, if it prov
Anionic Graft Copolymers Containing Poly(ethylene oxide)
Anionic graft copolymers were prepared through ring-opening anhydride reactions between poly(ethylene oxide) monomethyl ethers (MPEG) and copolymers of maleic anhydride and styrene (SMA), methyl vinyl ether (MEMA) and ethylene (EMA), respectively. The carboxylic acid groups in the graft copolymers were neutralized with KOH, and films were prepared by solution casting. The materials were characteri
Quantification of protein adducts of hexahydrophthalic anhydride and methylhexahydrophthalic anhydride in human plasma
Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two highly allergenic compounds used in the chemical industry. A method was developed for quantification of protein adducts of HHPA and MHHPA in human plasma. The plasma was dialysed and the anhydrides were hydrolysed from the proteins at mild acidic conditions. The released hexahydrophthalic acid (HHP acid) and m
Sensitivity of aerosol and cloud effects on radiation to cloud types: comparison between deep convective clouds and warm stratiform clouds over one-day period
Cloud and aerosol effects on radiation in two contrasting cloud types, a deep mesoscale convective system (MCS) and warm stratocumulus clouds, are simulated and compared. At the top of the atmosphere, 45-81% of shortwave cloud forcing (SCF) is offset by longwave cloud forcing (LCF) in the MCS, whereas warm stratiform clouds show the offset of less than similar to 20%. 28% of increased negative SCF
Fosterbarn ur ett könsperspektiv
Barns erfarenheter av separationer och placeringar utanför hemmet får vanligen så stor plats att de skymmer ålders och köns skillnader, vilket uppmärksammas i denna artikel. Som en del av ett större forsknings projekt granskas skillnader mellan 10-11 åriga pojkars och flickors problem.
Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke.
Aortic pathology revealed by MRI in patients with clinical suspicion of spinal disease
In five patients with clinical suspicion of spinal disease, MRI of the spine revealed unexpected aortic pathology explaining the symptoms. No significant intraspinal pathology was found on MRI. However, in one patient with clinical suspicion of spinal stenosis, an aortic occlusion was detected on MR images of the spine. The lower extremity ischaemia, caused by the occlusion, was responsible for th
TSP with neighborhoods of varying size
In TSP with neighborhoods (TSPN) we are given a collection S of regions in the plane, called neighborhoods, and we seek the shortest tour that visits all neighborhoods. Until now constant-factor approximation algorithms have been known only for cases where the neighborhoods are of approximately the same size. In this paper we present the first polynomial-time constant-factor approximation algorith
Shift catalysts in biomass generated synthesis gas
One of the CHRISGAS project objectives is to study the shift catalysts in biomass-generated synthesis gas. The water gas shift reaction is ruled by equilibrium, and the state of the gas can for a given H2/CO ratio be shifted by addition/removal of water, CO2 and/or by a change in the temperature. Stability area in respect to gas composition, sulphur content, pressure and temperature for FeCr shift
Phase Transformations, Ion-Exchange, Adsorption, and Dissolution Processes in Aquatic Fluorapatite Systems
A synthetic fluorapatite was prepared that undergoes a phase transformation generated during a dialysis step. A surface layer with the composition Ca(9)(HPO(4))(2)(PO(4))(4)F(2) is formed, which is suggested to form as one calcium atom is replaced by two protons. A surface complexation model, based upon XPS measurements, potentiometric titration data, batch experiments, and zeta-potential measurem
Role of gamma/delta T cell receptor-expressing lymphocytes in cutaneous infection caused by Staphylococcus aureus.
The high number of /-expressing T cells found in the epithelial lining layer suggests that they form a first line of defence against invading pathogens. To evaluate the role of / T cell-receptor (TCR)-expressing cells in cutaneous infection caused by Staphylococcus aureus, mice lacking /-expressing T cells (TCR/) were inoculated intradermally with S. aureus, and compared with S. aureus-infected co