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EDGE : What shapes the relationship between H i and stellar observables in faint dwarf galaxies?

We show how the interplay between feedback and mass-growth histories introduces scatter in the relationship between stellar and neutral gas properties of field faint dwarf galaxies (M∗ 106, M⊙). Across a suite of cosmological, high-resolution zoomed simulations, we find that dwarf galaxies of stellar masses 105 ≤ M∗ ≤ 106, M⊙ are bimodal in their cold gas content, being either H i-rich or H i-defi

On the formation and stability of cellulose-based emulsions in alkaline systems : Effect of the solvent quality

With amphiphilic properties, cellulose molecules are expected to adsorb at the O/W interface and be capable of stabilizing emulsions. The effect of solvent quality on the formation and stability of cellulose-based O/W emulsions was evaluated in different alkaline systems: NaOH, NaOH-urea and tetrabutylammonium hydroxide (TBAH). The optimal solvency conditions for cellulose adsorption at the O/W in

Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques

AIMS: Inflammation is a key factor in atherosclerosis. The transcription factor interferon regulatory factor-5 (IRF5) drives macrophages towards a pro-inflammatory state. We investigated the role of IRF5 in human atherosclerosis and plaque stability.METHODS AND RESULTS: Bulk RNA sequencing from the Carotid Plaque Imaging Project biobank were used to mine associations between major macrophage assoc

Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective

Recent studies highlight the importance of lipotoxic damage in aortic cells as the major pathogenetic contributor to atherosclerotic disease. Since the STE20-type kinase STK25 has been shown to exacerbate ectopic lipid storage and associated cell injury in several metabolic organs, we here investigate its role in the main cell types of vasculature. We depleted STK25 by small interfering RNA in hum

Linking silicon isotopic signatures with diatom communities

The use of silicon isotope ratios (expressed as δ30Si) as a paleolimnological proxy in lacustrine systems requires a better understanding of the role of lake processes in setting the δ30Si values of dissolved Si (dSi) in water and in diatom biogenic silica (bSi). We determined the δ30Si of modern dSi (δ30SidSi) and bSi (δ30SibSi) in three lakes in Lassen Volcanic National Park (LAVO), California (

Using Multivariate Imputation by Chained Equations to Predict Redshifts of Active Galactic Nuclei

Redshift measurement of active galactic nuclei (AGNs) remains a time-consuming and challenging task, as it requires follow up spectroscopic observations and detailed analysis. Hence, there exists an urgent requirement for alternative redshift estimation techniques. The use of machine learning (ML) for this purpose has been growing over the last few years, primarily due to the availability of large

Impact of SM parameters and of the vacua of the Higgs potential in gravitational waves detection

In this work we discuss two different phases of a complex singlet extension of the Standard Model (SM) together with an extension that also includes new fermion fields, in particular, a Majoron model equipped with an inverse seesaw mechanism. All considered scenarios contain a global U(1) symmetry and allow for first-order phase transitions while only two of them are strong enough to favour the de

Towards best practice recommendations for turbulence modelling of high-pressure homogenizer outlet chambers – Numerical validation using DNS data

There is a large interest in predicting high-pressure homogenizer (HPH) valve hydrodynamics using CFD, in academic research and industrial R&D. Most of these studies still use two-equation RANS turbulence models, whereas only a few have used LES formulations. From a theoretical perspective, LES is known to be more accurate than RANS, especially in terms of estimating the dissipation rate of tuThere is a large interest in predicting high-pressure homogenizer (HPH) valve hydrodynamics using CFD, in academic research and industrial R&D. Most of these studies still use two-equation RANS turbulence models, whereas only a few have used LES formulations. From a theoretical perspective, LES is known to be more accurate than RANS, especially in terms of estimating the dissipation rate of tu

Touching on elements for a non-invasive sensory feedback system for use in a prosthetic hand

Hand amputation results in the loss of motor and sensory functions, impacting activities of daily life and quality of life. Commercially available prosthetic hands restore the motor function but lack sensory feedback, which is crucial to receive information about the prosthesis state in real-time when interacting with the external environment. As a supplement to the missing sensory feedback, the a

Progress towards controlling the HIV epidemic in urban Ethiopia : Findings from the 2017–2018 Ethiopia population-based HIV impact assessment survey

Introduction In 2014, the Joint United Nations Programme on HIV/AIDS set an ‘ambitious’ 90-90-90 target for 2020. By 2016, there were disparities observed among countries in their progress towards the targets and some believed the targets were not achievable. In this report, we present the results of data from the Ethiopia Population-based HIV Impact Assessment survey analyzed to assess progress w

Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery

Stem cell therapies for Parkinson’s disease (PD) have entered first-in-human clinical trials using a set of technically related methods to produce mesencephalic dopamine (mDA) neurons from human pluripotent stem cells (hPSCs). Here, we outline an approach for high-yield derivation of mDA neurons that principally differs from alternative technologies by utilizing retinoic acid (RA) signaling, inste

Condom failure and pre-exposure prophylaxis use experience among female sex workers in Ethiopia : a qualitative study

BACKGROUND: Female sex workers (FSW) remain a highly exposed group for HIV/STIs due to different factors including condom failure. In Ethiopia, pre-exposure prophylaxis (PrEP) has recently been introduced as an intervention strategy to prevent new HIV infections, but knowledge about FSWs' experiences of condom failure and PrEP use remains scarce. Therefore, this study explores FSWs' experiences co

Uncle Tall Tale : On “Mo Yan Speaks: Lectures and Speeches by the Nobel Laureate from China”

ALTHOUGH MO YAN’S claim to fame is undoubtedly as the Nobel laureate from China, the 23 public lectures gathered in Mo Yan Speaks present a truly “glocal” writer who has one literary foot firmly planted in the soil of his native Gaomi Township and the other tiptoeing into the arena of world literature. They show an author performing a balancing act between his international elite status and the lo

From Sweden to America: Migrant Selection in the Transatlantic Migration, 1890-1910

We examine selection by class origin and gender in the emigration from Sweden to the United States during the age of mass migration. We use full-count census data linked to emigration lists to create a panel of over one million men and women. Class selection was similar for men and women, with children from medium-skilled backgrounds being most likely to leave. Selection on class origin was most p

The scale of a martian hydrothermal system explored using combined neutron and x-ray tomography

Nakhlite meteorites are igneous rocks from Mars that were aqueously altered ~630 million years ago. Hydrothermal systems on Earth are known to provide microhabitats; knowledge of the extent and duration of these systems is crucial to establish whether they could sustain life elsewhere in the Solar System. Here, we explore the three-dimensional distribution of hydrous phases within the Miller Range

Taking a Deep Breath : an Examination of Current Controversies in Surgical Procedures in Lung Transplantation

Purpose of Review: This article reviews controversial questions within the field of lung transplantation, with a focus on data generated within the last 3 years. We aim to summarize differing opinions on a selection of topics, including bridge-to-transplantation, intraoperative machine circulatory support, bronchial anastomosis, size mismatch, delayed chest closure, and ex vivo lung perfusion.Rece

Relativistic, model-independent determination of electromagnetic finite-size effects beyond the pointlike approximation : Relativistic, model-independent determination of electromagnetic finite-size effects beyond the pointlike approximation

We present a relativistic and model-independent method to derive structure-dependent electromagnetic finite-size effects. This is a systematic procedure, particularly well-suited for automation, which works at arbitrarily high orders in the large-volume expansion. Structure-dependent coefficients appear as zero-momentum derivatives of physical form factors which can be obtained through experimenta

40 Hz invisible spectral flicker and its potential use in Alzheimer's light therapy treatment

Alzheimer's disease (AD) not only takes an emotional toll on the individual with the disease, their families, relatives, and caretakers, it also has immense socioeconomic consequences on the health care system and society. Moreover, the socioeconomic consequences are expected to increase significantly, thus reducing the social and economic cost of AD is of high importance. Recently, exposure to 40