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A GaAs-based resonant tunneling permeable base transistor has been developed and evaluated at room temperature. The transistor is fabricated by overgrowing a tungsten gate placed next to an AlGaAs-GaAs-InGaAs resonant tunneling heterostructure. By changing the gate voltage, the effective conducting area of the tunnel diode can be modulated and the collector-emitter current thus controlled. Peak cu
The paper describes a project aiming at the construction of functional mimics of the oxygen evolving complex of Photosystem II, coupled to photoinduced charge separation. Biomimetic electron donors - manganese complexes and tyrosine - have been linked to a Ru(II)-polypyridine photosensitizer. Oxidation of the donors by intramolecular electron transfer from the photo-oxidized Ru(III) complex was de
Two different flexible osmium functionalised polymers were investigated for their ability to efficiently "wire" pyranose oxidase when immobilised on graphite electrodes. The two Os-polymers differ in redox potential and the length of the side chains, where the Os2+/3+-functionalities are located. The performance of the redox polymers as mediators for the enzyme was tested with glucose. As well as
BACKGROUND: The acquisition of drug resistance is a major reason for poor outcome of neuroblastoma. Protein kinase C (PKC) has been suggested to influence drug resistance in cancer cells. The aim of this study was to elucidate whether inhibition of PKCbeta isoforms influences drug-resistance of neuroblastoma cells. METHODS: The effect of the PKCbeta inhibitor LY379196 on the growth-suppressing eff
Repeated resistivity measurement is a potentially powerful method for monitoring development of internal erosion and anomalous seepage in earth embankment dams. This study is part of a project to improve current longterm monitoring routines and data interpretation and increasing the understanding when interpreting existing data. This is accomplished by modeling various occurrences typical of emban
This paper addresses a problem for theories of epistemic democracy. In a decision on a complex issue which can be decomposed into several parts, a collective can use different voting procedures: Either its members vote on each sub-question and the answers that gain majority support are used as premises for the conclusion on the main issue (premise based-procedure, pbp), or the vote is conducted on
On the Swedish artistis Dick Bengtsson, Elis Eriksson and Jarl Hammarberg and their role in the introduction of installation art in Sweden.
The spectroscopic data mercury (Hg) I and Hg II was analyzed from beam-foil spectroscopy. The wavelength was found to be of course fixed and independent of the light source and recording conditions. It was found that if the calculated branching ratio was correct, then the Hg II was an important constituent of fluorescent light tube plasmas. The wavelength region from 40 to 600 nm in overlapping wa
While the scientist-practitioner model of training has enjoyed wide-spread appeal, difficulties in implementing the model have continued since its inception. Despite these difficulites, we remain advocates of the model and believe responsibility for inculcating a scientist-practitioner mindset rests with both training programs and trainees themselves. Thus, we offer several suggestions for both tr
Oral and pharyngeal function in 131 institutionalized elderly patients with advanced dementia was evaluated by means of videofluoroscopic deglutition examination (VDE). Findings were normal in only nine (7%) patients. Oral-stage dysfunction was observed in 93 (71%) patients, pharyngeal dysfunction in 56 (43%), and pharyngoesophageal-segment abnormalities in 43 (33%). Multiple-stage dysfunction was
Due to uncertainties regarding clinically meaningful gains from adjuvant chemotherapy after colorectal cancer surgery, several Nordic Groups in the early 1990s initiated randomised trials to prove or reject such gains. This report gives the joint analyses after a minimum 5-year follow-up. Between October 1991 and December 1997, 2 224 patients under 76 years of age with colorectal cancer stages II
Background/Aims: Budesonide controlled-release (CR) capsules are effective for inducing remission of Crohn's disease (CD) and are associated with fewer side effects than conventional corticosteroids. A compassionate-use program was implemented in countries where this treatment was unavailable. This paper reports the findings of this program. Methodology: Physicians were allowed to apply to AstraZe
