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The metabolic syndrome - What is it and how should it be managed?

A cluster of metabolic factors have been merged into an entity named the metabolic syndrome. Although the characteristics of this syndrome have varied over time the presently used definition was established in 2009. The presence of three abnormal findings out of five components qualifies a person for the metabolic syndrome: elevated waist circumference, elevated triglycerides, reduced high-density

Comparison of Normal and Metaplastic Epithelium in Patients with Stable versus Persistently Symptomatic Severe Asthma Using Laser-Capture Microdissection and Data-Independent Acquisition–Mass Spectrometry

A proportion of patients with severe asthma (SA) show poor responses to traditional asthma medications; however, it remains unknown why some patients remain persistently symptomatic. Our objective was to explore the use of laser-capture microdissection of specific epithelial structures combined with quantitative data-independent acquisition mass spectrometry to elucidate differences in protein com

Local Governance of Greenhouse Gas Emissions from Air Travel

Global greenhouse gas emissions from air travel (GHG-A) are on the rise, and projections point towards a rapid growth in the coming decades. This study aims to examine how local government (cities), addresses GHG-A in their Sustainable Energy Action Plans (SEAP). To fulfil this aim, over 200 SEAPs were analysed focusing on three issues: (1) Treatment of GHG-A in local emissions inventories; (2) PoGlobal greenhouse gas emissions from air travel (GHG-A) are on the rise, and projections point towards a rapid growth in the coming decades. This study aims to examine how local government (cities), addresses GHG-A in their Sustainable Energy Action Plans (SEAP). To fulfil this aim, over 200 SEAPs were analysed focusing on three issues: (1) Treatment of GHG-A in local emissions inventories; (2) Po

Spatial vision and visually guided behavior in apidae

The family Apidae, which is amongst the largest bee families, are important pollinators globally and have been well studied for their visual adaptations and visually guided behaviors. This review is a synthesis of what is known about their eyes and visual capabilities. There are many species-specific differences, however, the relationship between body size, eye size, resolution, and sensitivity sh

Interpreters in healthcare : Nursing perspectives

PURPOSE: This study explored nursing experiences using interpreters in primary healthcare settings. METHODS: Eight nurses in southern Sweden were subjected to semistructured interviews. The responses were divided into three categories using content analysis: interpreter influence, challenges, and strategies. RESULTS: Despite using an interpreter to minimize language barriers, nurses do not achieve

Data for assessment of soil water extractable and percolation water dissolved organic carbon in watersheds

(“Sources of soil dissolved organic carbon in a mixed agricultural and forested watershed in Rwanda”, [6]) This data article presents water extractable organic carbon (WEOC), percolation water dissolved organic carbon (pDOC), and mean antecedent precipitation indices (API) and mean antecedent temperature (MAT) data. The article also presents edaphic properties such soil texture elements, total org

Determining the Predominant Lesion in Patients With Severe Aortic Stenosis and Coronary Stenoses : A Multicenter Study Using Intracoronary Pressure and Flow

BACKGROUND: Patients with severe aortic stenosis (AS) often have coronary artery disease. Both the aortic valve and the coronary disease influence the blood flow to the myocardium and its ability to respond to stress; leading to exertional symptoms. In this study, we aim to quantify the effect of severe AS on the coronary microcirculation and determine if this is influenced by any concomitant coro

Physiotherapist-led treatment for young to middle-aged active adults with hip-related pain : Consensus recommendations from the International Hip-related Pain Research Network, Zurich 2018

The 1st International Hip-related Pain Research Network meeting discussed four prioritised themes concerning hip-related pain in young to middle-aged adults: (1) diagnosis and classification of hip-related pain; (2) patient-reported outcome measures for hip-related pain; (3) measurement of physical capacity for hip-related pain; (4) physiotherapist-led treatment for hip-related pain. Thirty-eight

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2

Thermosensitive transient receptor potential (TRP) ion channels detect changes in ambient temperature to regulate body temperature and temperature-dependent cellular activity. Rodent orthologs of TRP vanilloid 2 (TRPV2) are activated by nonphysiological heat exceeding 50 °C, and human TRPV2 is heat-insensitive. TRPV2 is required for phagocytic activity of macrophages which are rarely exposed to ex

Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle : A UK Biobank study

Aims: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known. Methods: Information on usual walking pace (self-defined as slow, steady/average, or brisk), dynamometer-assessed handgrip strength, lifestyle behaviours (physical activity, TV viewing, diet, alcohol intake,

Searching for Atrial Fibrillation Poststroke : A White Paper of the AF-SCREEN International Collaboration

Cardiac thromboembolism attributed to atrial fibrillation (AF) is responsible for up to one-third of ischemic strokes. Stroke may be the first manifestation of previously undetected AF. Given the efficacy of oral anticoagulants in preventing AF-related ischemic strokes, strategies of searching for AF after a stroke using ECG monitoring followed by oral anticoagulation (OAC) treatment have been pro

Thermodynamic uncertainty relations including measurement and feedback

Thermodynamic uncertainty relations quantify how the signal-to-noise ratio of a given observable is constrained by dissipation. Fluctuation relations generalize the second law of thermodynamics to stochastic processes. We show that any fluctuation relation directly implies a thermodynamic uncertainty relation, considerably increasing their range of applicability. In particular, we extend thermodyn

Conductive and enzyme-like silk fibers for soft sensing application

A combination of supercritical carbon dioxide (scCO2) impregnation of pyrrole and sonochemical transformation of permanganate (KMnO4) was used to impart conductive and catalytic properties to silk fibers. The results indicated that the conductivity (from polypyrrole –PPy) and catalytic activities (from manganese dioxide –MnO2) were independent and complementary within the processing parameters use

Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis

The blood-brain barrier (BBB) is formed by the endothelial cells lining cerebral microvessels, but how blood-borne signaling molecules influence permeability is incompletely understood. We here examined how the apolipoprotein M (apoM)-bound sphingosine 1-phosphate (S1P) signaling pathway affects the BBB in different categories of cerebral microvessels using ApoM deficient mice (Apom-/-). We used t

Performing the Other : Report on workshops on Copying and Imitating

Performing The Other. Report on workshops on observing and imitatingThe lecture will present the experience, results and challenges arising within a series of workshops that were investigating the role of observation, copying and imitation in the actor’s work, activities close to Brecht’s aesthetic focus. Claiming that “people will observe you, in order to investigate how well you have observed”,

Imitation as vehicle – and memory as hindrance

What is the relationship between identity, representation and memory in contemporary performance practices? Does memory function as a basic tool in artist’s work or can it also be regarded as a hindrance?In current performance art, identity is often defined as an accumulation of one’s embodied experience and memory. The artist’s body can be seen as an archive which is re-enacted in the encounter w

African Economic Growth 1900-50: Historical National Accounts for British Colonial Africa

The study of growth in African economies during the 20th Century is hampered by the lack of historical GDP estimates. There has been some backward projections, and country case studies, but despite the available data historical national accounts has not yet been assembled. This paper provides GDP estimates for some former British colonies between 1900 – 1950. The estimates indicate faster growth a

The Problems of Economic Data in Africa

The study of economic development in African countries is facing a basic problem of lack of reliable data and statistics. These problems of economic data are best addressed under three main categories: design, capacity, and politics. The focus is on gross domestic product (GDP), but the relevance goes beyond GDP statistics because the aggregate of GDP requires economic data on all sectors of the e