Recombination plays a crucial role in evolution by generating novel haplotypes and disrupting linkage between genes, thereby enhancing the efficiency of selection. Here, we analyze the genomes of 12 great reed warblers (Acrocephalus arundinaceus) in a 3-generation pedigree to identify precise crossover positions along the chromosomes. We located more than 200 crossovers and found that these were h

Background Frequent hemodialysis provided more than three times per week may lower mortality and improve health-related quality of life. Yet, the evidence is inconclusive. We evaluated the benefits and harms of frequent hemodialysis in people with kidney failure compared with standard hemodialysis. Methods We performed a systematic review of randomized controlled trials including adults on hemodia

Cardiovascular (CV) morbidity and mortality is high in patients with chronic kidney disease (CKD). Most patients reveal a high prevalence of CV risk factors such as diabetes or arterial hypertension and many have manifest cardiovascular disease (CVD), such as coronary artery disease and chronic heart failure with an increased risk of clinical events including sudden cardiac death. Diabetes mellitu

Some visual neurons in the dragonfly (Hemicordulia tau) optic lobe respond to small, moving targets, likely underlying their fast pursuit of prey and conspecifics. In response to repetitive targets presented at short intervals, the spiking activity of these “small target motion detector” (STMD) neurons diminishes over time. Previous experiments limited this adaptation by including intertrial rest

Observed rotational bands that terminate or appear to terminate at very high spin are analyzed within the configuration constrained cranked Nilsson-Strutinsky (unpaired CNS or CNSB with pairing) formalism. Spin values for the nuclei discussed reach or come close to the maximum spin that can be built within the Z,N=50-82 shells. Configurations are distinguished not only by the number of particles i

Infectious, inflammatory and autoimmune conditions present differently in males and females. SARS-CoV-2 infection in naive males is associated with increased risk of death, whereas females are at increased risk of long COVID1, similar to observations in other infections2. Females respond more strongly to vaccines, and adverse reactions are more frequent3, like most autoimmune diseases4. Immunologi

Gastric cancer represents a serious health problem worldwide, with insufficient molecular biomarkers and therapeutic options. Consequently, several efforts have been directed towards finding specific disease markers in order to develop new therapies capable of defeating gastric cancer. Attention has been pointed to cancer stem cells (CSCs) as they are primarily responsible for tumor initiation and

Våld i nära relation, och då främst mäns våld mot kvinnor är ett stort samhällsproblem. Som sjukvårdspersonal fyller vi en viktig funktion i att fånga upp individer som utsätts eller riskerar att utsättas för våld. Våldsutsatta söker sig till akutmottagningar eller annan akutvårdsinstans, vilket innebär att sjuksköterskor verksamma inom akutsjukvården kan fylla en livsviktig funktion i att uppmärk

Statistics reveal the concerning prevalence of mental health issues among Swedish public sector managers, highlighting the critical need for deeper insights into the relevance of social support in coping with work-related stress. This study aims to examine the relevance of various sources of social support for managers coping with work-related stress, an area relatively underexplored in public adm

Heavy metal (HM) pollution remains a pressing global concern, affecting soil regarding food safety, and negatively influencing the UN Sustainable Development Goals (SDGs). We investigated the efficacy of untreated cypress biochar (UCB) and Ca-modified cypress biochar (MCB) in mitigating HM contamination and enhancing growth across native and contaminated soils (40 mg/kg) in carrot pot experiments.

The transition from InterBank Offered Rates (IBORs) to Risk-Free Rates (RFRs) represents one of the most significant shifts in modern financial markets. This transition addresses concerns about the reliability and transparency of IBORs by adopting benchmarks based on actual market transactions. However, this change has far-reaching implications for the valuation of complex financial instruments, s

This thesis examines the imagery of the mythological character Omphale in Roman art, from the late Republic to the end of the Severan period; in a qualitative collection of images containing sculptures, wall paintings, jewellery and gemstones. This myth portrays a rather different, and somewhat provocative female character that was adapted from Greek mythology into Roman culture in the last centur

Abstract: This thesis is an attempt to evaluate the pre-Christian and Christian and cult-place continuity question. This is done by investigating intervisibility between Christian Churches and pre-Christian grave monuments within the province of Halland, Sweden. This analysis was done via large statistical GIS databases of which viewshed analysis was applied to, which in turn was then interpreted

Background: Lifestyle interventions aiming to improve dietary habits, increase physical activity level, and improve emotional well-being can positively impact clinical outcomes in patients with chronic kidney disease (CKD). Educational material for health care professionals working with CKD patients that focuses on why and how to promote lifestyle changes is lacking. The present study aims to depi

Background: In-center hemodialysis (IHD) is the most common dialysis modality. Assisted peritoneal dialysis (assPD) is an option for frail and/or incapacitated patients. Both modalities can be used to alleviate uremic symptoms towards the end of life. There are few studies comparing these modalities. The primary aim is to compare hospital admissions between assPD and IHD. The secondary aim is to c

Epigenetic deregulation through altered DNA methylation is a fundamental feature of tumorigenesis, but tumor data from bulk tissue samples contain different proportions of malignant and non-malignant cells that may confound the interpretation of DNA methylation values. The adjustment of DNA methylation data based on tumor purity has been proposed to render both genome-wide and gene-specific analys

Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide. While sociodemographic, dietary and lifestyle factors have been well documented in relation to CVD, environmental factors have been less studied. However, considering the ongoing biodiversity, climate, and health crises, it is imperative to better understand the interplay between the environment and health. Thi

The Sensory Processing Measure, second edition (SPM-2), is an American assessment guiding person-centered sensory processing interventions, but it lacks Swedish adaptation for occupational therapists. In eight phases, this study translated the SPM-2 into Swedish and assessed its face validity and preliminary psychometric properties, including internal consistency and inter-scale/item correlations.