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Background: Postmastectomy radiotherapy (PMRT) impairs the outcome of immediate breast reconstruction in patients with breast cancer, and the sentinel lymph node (SLN) status is crucial in evaluating the need for PMRT. The aim of this study was to develop and validate models to stratify the risk of clinically significant SLN macrometastases (macro-SLNMs) before surgery. Methods: Women diagnosed wi

INTRODUCTION: We evaluated differences in p-tau levels between Alzheimer's disease (AD), a condition with brain-specific changes in p-tau, and amyotrophic lateral sclerosis (ALS), a condition associated with increases in peripheral p-tau levels. METHODS: Cerebrospinal fluid and plasma from 668 participants were analyzed using immunoassays specific for the low-molecular-weight (LMW) tau isoforms pr

Peacebuilding initiatives play an important role in the reconstruction of political, economic, and social conditions after internal armed conflicts. If these initiatives also account for environmental aspects, they have the potential to address both ecological damages and resource-related conflict causes. The sprawling literature on environmental peacebuilding therefore stresses the need for a hol

Long-term population studies can identify changes in population dynamics over time. However, to realize meaningful conclusions, these studies rely on accurate measurements of individual traits and population characteristics. Here, we evaluate the accuracy of the observational methods used to measure reproductive traits in individually marked black-tailed godwits (Limosa limosa limosa). By comparin

There is a growing consensus that global monitoring of water access greatly underestimates household water insecurity worldwide. Measures that overlook the intricacies of accessing water lead to an overinflated sense of progress towards universal water access. This article illustrates the complexity of household water access by revealing the causes and impacts of household water insecurity in the

OBJECTIVES: This study evaluated the long-term risk of permanent pacemaker implantation following Cox-maze IV (CMIV) and concurrent mitral valve surgery. METHODS: A retrospective, nationwide, registry-based analysis was conducted on postoperative permanent pacemaker implantation in 397 patients with symptomatic mitral valve insufficiency and atrial fibrillation who underwent CMIV and mitral valve

Most natural populations are genetically diverse. Understanding how diversity is maintained and distributed across time and space can provide insights into the potential for evolution and extinction of populations. Immunogenetic diversity aids individuals and populations in resisting infectious disease, with many studies linking resistance to genes encoding adaptive immune responses, such as the m

In this work, four dyes—consisting of heteroleptic iron N-heterocyclic carbene (NHC) complexes—were investigated in dye-sensitized solar cell (DSC) applications to explore their behavior and interactions with the overall cell. Three of the four dyes contained amino-based electron donor moieties, while one was without this type of structure, and instead had only a hydrogen atom. Compared to earlier

Statistical Jump Models are a class of regime identification models,similar to Hidden Markov Models, with the added advantage of facilitatinglarge-scale integration of exogenous variables that influence thelatent regime-switching process. Recent advancements in SJMs includethe introduction of automatic feature selection techniques, which eliminateirrelevant exogenous information and enhance the mo

Teachers are now encouraged to use generative artificial intelligence (GenAI) tools to complete various school-related administrative tasks, with the promise of saving considerable amounts of time and effort. Drawing on interviews from 57 teachers across eight schools in Sweden and Australia, this paper explores teachers’ experiences when working with GenAI. In particular, it focuses on the large

Background and aimHypoxic-ischaemic encephalopathy (HIE) is a leading cause of morbidity and mortality in unconscious patients resuscitated after out-of-hospital cardiac arrest. Many patients die after withdrawal of life-sustaining treatments (WLST), often due to a presumed poor prognosis. To minimise the risk of premature WLST, guidelines recommend using a multimodal prognostication. Head compute

Från Gotland till Venedig. Turismen är livsviktig för många orter. Men i takt med att besökarna ökar, växer också kritiken mot den nya formen av kapitalism den medför.

I en tid präglad av konvergenskultur har en undervisningsdesign baserad på transmedialitet skapats för studenter på ämneslärarprogrammet i svenska för att dels visa på alternativa sätt att analysera dikter, dels visa på alternativa sätt att undervisa i lyrik och lyrikanalys och därigenom vidga den litteraturdidaktiska repertoaren för framtidens ämneslärare. Syftet med studien är att undersöka lära

Mot bakgrund av samhälleliga förändringar är artikelns syfte att bidra med kunskap om hur en undervisningsdesign som utmärks av upplösta gränser mellan estetiska och mediala uttrycksformer, och som sätter berättelser i centrum, kan synliggöra och möjliggöra elevers individuella och kollektiva meningsskapande och uppmuntra till nyfikenhet och förståelse för andra och för andras berättelser, för att

Sweden has swiftly transitioned from being considered a progressive pioneer in climate mitigation to the forefront of late obstruction. The proximate cause was the general elections in 2022, after which the Sweden Democrats (SD) gained authority over the country's climate policies. This paper explores how the far right turned Sweden from a (reputed) pioneer of climate mitigation to an obstructor,

Protein crystallization is key to determining the structure of proteins at atomic resolution. It can occur naturally, including in pathological pathways, for instance with aquaporin and γ-crystallin proteins. A fundamental understanding of the underlying crystallization process is both technologically and biologically relevant. A multitechnique approach is employed here to investigate protein crys

The building and construction industry is responsible for around 40% of global greenhouse gas emissions, driving the urgent need for new regulations. As such, the life cycle assessment (LCA) methodology has become fundamental for evaluating environmental impacts. Despite the need for digital tools to support environmental performance evaluations, the lack of guidance on developing such tools hindeThe building and construction industry is responsible for around 40% of global greenhouse gas emissions, driving the urgent need for new regulations. As such, the life cycle assessment (LCA) methodology has become fundamental for evaluating environmental impacts. Despite the need for digital tools to support environmental performance evaluations, the lack of guidance on developing such tools hinde

Our viewpoint highlights the challenges faced by women in the Induced Polarization (IP) community (and elsewhere), particularly the persistent gender imbalance in scientific workshops. This underrepresentation in leadership roles, presentations and discussions reflects broader systemic biases in academia. By sharing the experience of the 7th IP workshop, where the organizing team made deliberate eff

Characterizing ore deposits or mining dumps in terms of mineral content and grain size remains a challenge. Since the 1950s the induced polarization (IP) method has been successfully applied in ore prospecting. However, reliably interpreting field survey data requires comprehensive laboratory studies to establish a link between the IP parameters from empirical or phenomenological models and the typ

Human activities in deciduous forests over the past centuries have influenced associated species. To reduce extinction risks and mitigate population declines, there is growing interest in forest conservation and restoration, including initiatives by the European Union (EU). For resulting restoration and conservation practices to succeed, it is essential to know which forest characteristics promote