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The extreme light infrastructure—attosecond light pulse source (ELI-ALPS) project

Globally, large international research infrastructures have over many decades promoted excellence in science and technology. Aligned with the international practice, the Europe Strategy Forum for Research Infrastructures (ESFRI) has developed and keeps updating a roadmap for research infrastructures. The Extreme Light Infrastructure (ELI) is one of the two large scale Laser Research Infrastructure

Feminism

Historic differences in livelihoods, work roles and the access to resources lead to differences in how women and men are exposed to and impacted by climate change. Policymakers and civil society groups have come to realize that gender matters in the governance of climate issues and there is an emerging scholarship in this field. However, the attention is mainly on women, rather than on gender, for

Security

This chapter offers a review of the literature in the field of critical security studies in order to discuss the various social constructions of climate change as a security issue and their policy implications. Will climate security discourse facilitate climate mitigation policy? First, the Copenhagen School asks whether extraordinary measures to protect the climate (including emission reductions)

An Expanded Multi-Organ Disease Phenotype Associated with Mutations in YARS

Whole exome sequence analysis was performed in a Swedish mother-father-affected proband trio with a phenotype characterized by progressive retinal degeneration with congenital nystagmus, profound congenital hearing impairment, primary amenorrhea, agenesis of the corpus callosum, and liver disease. A homozygous variant c.806T > C, p.(F269S) in the tyrosyl-tRNA synthetase gene (YARS) was the only id

Legal Aid in Sweden

Sweden has a combination of public and private protection of legal expenses in civil cases. The public legal aid scheme is subsidiary to the legal expense insurance, which means anyone who had a legal expense insurance covering the current affair would not receive legal aid. The chapter aims at reviewing the current legal aid in the country with emphasis on the public legal aid scheme and the lega

Tumor characteristics and prognosis in women with pregnancy-associated breast cancer

There is evidence of poor prognosis in women with pregnancy-associated breast cancer (PABC) diagnosed during pregnancy or within 2 years of delivery. Using a large, population-based cohort, we examined clinicopathologic features and survival in women with PABC. A cohort of women diagnosed with invasive breast cancer between 1992 and 2009 at ages 15-44 years was identified in the Swedish Cancer Reg

Parental health and psychosomatic symptoms in preschool children : A cross-sectional study in Scania, Sweden

Aim: The aim of the study was to assess the association between parental self-rated health and recurrent abdominal pain (RAP) in preschool children. Methods: A questionnaire, including questions about sociodemographic and psychosocial factors, lifestyle, parental and child health, was sent to parents of all 4-year-old children in Scania, Sweden. The response rate was 43.6%. The outcome was RAP and

Cadmium, carotid atherosclerosis, and incidence of ischemic stroke

Background--Exposure to cadmium has been associated with carotid plaques, inflammation in carotid plaques, and increased risk of ischemic stroke. This study examined the separate and interacting effects of blood cadmium levels and carotid plaques on the risk of incident ischemic stroke. Methods and Results--Cadmium levels were measured in 4156 subjects (39.2% men; mean ± SD age 57.3 ± 5.9 years) w

Study of Flare Assessment in Systemic Lupus Erythematosus Based on Paper Patients

Objective: To determine the level of agreement of disease flare severity (distinguishing severe, moderate, and mild flare and persistent disease activity) in a large paper-patient exercise involving 988 individual cases of systemic lupus erythematosus. Methods: A total of 988 individual lupus case histories were assessed by 3 individual physicians. Complete agreement about the degree of flare (or

Simplicity at the cost of predictive accuracy in diffuse large B-cell lymphoma : A critical assessment of the R-IPI, IPI, and NCCN-IPI

The international prognostic index (IPI) and similar models form the cornerstone of clinical assessment in newly diagnosed diffuse large B-cell lymphoma (DLBCL). While being simple and convenient to use, their inadequate use of the available clinical data is a major weakness. In this study, we compared performance of the International Prognostic Index (IPI) and its variations (R-IPI and NCCN-IPI)

Om ADO:s första fyrtio år

Recension av ADO. Assyriska Demokratiska Organisationen 1957-1999. Organisatoriska, socio-politiska och kulturella aspekter. En kortfattad historik

Brief Report : Rituximab for the Treatment of Adult-Onset IgA Vasculitis (Henoch-Schönlein)

Objective: Adult-onset IgA vasculitis (Henoch-Schönlein) (IgAV) is a rare systemic vasculitis characterized by IgA1-dominant deposits. The treatment of adult-onset IgAV is controversial and is based on the combination of glucocorticoids and immunosuppressive agents, but many patients have refractory or relapsing disease despite treatment. Rituximab (RTX) is a B cell–depleting antibody of proven ef

Imaging brain microstructure with diffusion MRI : Practicality and applications

This article gives an overview of microstructure imaging of the brain with diffusion MRI and reviews the state of the art. The microstructure-imaging paradigm aims to estimate and map microscopic properties of tissue using a model that links these properties to the voxel scale MR signal. Imaging techniques of this type are just starting to make the transition from the technical research domain to

Home setting after stroke, facilitators and barriers : A systematic literature review

This paper seeks to improve the understanding of the interaction between patients with stroke and the physical environment in their home settings. Stroke care is increasingly performed in the patient's home. Therefore, a systematic review was conducted to identify the existing knowledge about facilitators and barriers in the physical environment of home settings for the stroke rehabilitation proce