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Adherence to optimal heart rate control in heart failure with reduced ejection fraction : insight from a survey of heart rate in heart failure in Sweden (HR-HF study)

Introduction: Despite that heart rate (HR) control is one of the guideline-recommended treatment goals for heart failure (HF) patients, implementation has been painstakingly slow. Therefore, it would be important to identify patients who have not yet achieved their target heart rates and assess possible underlying reasons as to why the target rates are not met. Materials and methods: The survey of

Perceived consequences of ageing with late effects of polio and strategies for managing daily life : A qualitative study

Background: New or increased impairments may develop several decades after an acute poliomyelitis infection. These new symptoms, commonly referred to as late effects of polio (LEoP), are characterised by muscular weakness and fatigue, generalised fatigue, pain at rest or during activities and cold intolerance. Growing older with LEoP may lead to increased activity limitations and participation res

Middle-aged patients with an MRI-verified medial meniscal tear report symptoms commonly associated with knee osteoarthritis : A cross-sectional study of 199 patients

Background and purpose — No consensus exists on when to perform arthroscopic partial meniscectomy in patients with a degenerative meniscal tear. Since MRI and clinical tests are not accurate in detecting a symptomatic meniscal lesion, the patient’s symptoms often play a large role when deciding when to perform surgery. We determined the prevalence and severity of self-reported knee symptoms in pat

The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin

Metformin is widely used in the treatment of type 2 diabetes to lower blood glucose. Although metformin is a relatively safe and effective drug, its clinical efficacy is variable and under certain circumstances it may contribute to life-threatening lactic acidosis. Thus, additional understanding of metformin pharmacokinetics and pharmacodynamics could provide important information regarding therap

The Naturalisation of Growth: Marx, the Regulation Approach and Bourdieu

The paper analyses the hegemony of the growth paradigm through the example of its naturalisation in capitalist production and consumption relations. Applying a combination of theoretical elements from the Marxian tradition, the Regulation approach and Bourdieusian sociology, emphasis is placed on how the growth imperative is reflected in people’s minds and bodies. It becomes hegemonic because it a

Reduction of rod and cone function in 6.5-year-old children born extremely preterm

OBJECTIVE To compare retinal function via full-field electroretinographic (ffERG) recordings in 6.5-year-old children born extremely preterm with children born at term. DESIGN, SETTING, AND PARTICIPANTS A subcohort studywas conducted from July 1, 2010, to January 15, 2014, of the national Extremely Preterm Infants in Sweden Study, including preterm children (

The formant dynamics of long close vowels in three varieties of Swedish

This study compares the acoustic realisation of /iː yː ʉː uː/ inthree varieties of Swedish: Central Swedish, Estonian Swedish, and Finland Swedish. Vowel tokens were extracted from isolated words produced by six elderly female speakers from each variety. Trajectories of the first three formants were modelled with discrete cosine transform (DCT) coefficients, enabling the comparison of the formant This study compares the acoustic realisation of /i: y: ʉ: u:/ in three varieties of Swedish: Central Swedish, Estonian Swedish, and Finland Swedish. Vowel tokens were extracted from isolated words produced by six elderly female speakers from each variety. Trajectories of the first three formants were modelled with discrete cosine transform (DCT) coefficients, enabling the comparison of the formant

Deliberate self-harm behavior among young violent offenders

Deliberate self-harm behavior (DSH) can have profound effects on a person’s quality of life, and challenges the health care system. Even though DSH has been associated with aggressive interpersonal behaviors, the knowledge on DSH in persons exhibiting such behaviors is scarce. This study aims to (1) specify the prevalence and character of DSH, (2) identify clinical, neurocognitive, psychosocial, a

The Compare-Acute trial of fractional flow reserve-guided multivessel angioplasty in myocardial infarction

The Compare-Acute trial demonstrates the relative safety and utility of performing multivessel FFR to examine the significance of non-culprit lesions during primary PCI. Patients who had an FFR-guided PCI strategy for non-culprit lesions during the index hospitalisation had fewer adverse cardiovascular events, essentially unplanned revascularisations, as compared to patients who were treated for t

High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

Background: High expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate, with prolonged survival in several malignant diseases and with the benefit of platinum-based chemotherapy in ovarian cancer. The aim of this study was to evaluate RBM3 in metastatic colorectal cancer (mCRC) as a prognostic factor for overall survival and in relation to benefit of first-line chemother

Firefighter fatalities in Sweden, 1937 - 2016

The purpose of this work was to present collective data on firefighter fatalities in Sweden between 1937 and 2016. Data presented is directly related to operations only. Fatalities due to long-term exposure of gases, particles, and physical/psychological stress or similar were not included in the study. Also, accidents involving ambulances as well as fatalities in direct relation to physical trainThe purpose of this work was to present collective data on firefighter fatalities in Sweden between 1937 and 2016. Data presented is directly related to operations only. Fatalities due to long-term exposure of gases, particles, and physical/psychological stress or similar were not included in the study. Also, accidents involving ambulances as well as fatalities in direct relation to physical train

Lyckade häckningar i samma holk av tornseglare Apus apus och rödstjärt phoenicurus phoenicurus

During the spring 2015, a pair of Common Redstarts Phoenicurus phoenicurus successfully raised a five-chick brood in an artificial nest-box designed for and occupied by a pair of Common Swifts Apus apus in southern Sweden. The breeding was monitored by a nest-box camera, which recorded close interactions between the two species. The Common Redstarts initiated the breeding first and had young in th

The Unbound Brain

Special issue of "Culture Unbound". Through six original articles, the issue investigates a variety of cultural and scientific discourses and practices that in different ways are related to neuroscience and the brain.

BrownoutCC: Cascaded Control for Bounding the Response Times of Cloud Applications

Cloud computing has emerged as an inexpensive and powerful computing paradigm, to the point that now even applications with hard deadlines are executed in the cloud. It may happen, due to unexpected events, that an application becomes popular and receives a lot of attention and client requests in a short period of time. Provisioning computing capacity for such applications is quite a difficult tas

Economic consequences of mastitis and withdrawal of milk with high somatic cell count in Swedish dairy herds

The main aim was to assess the impact of mastitis on technical and economic results of a dairy herd under current Swedish farming conditions. The second aim was to investigate the effects obtained by withdrawing milk with high somatic cell count (SCC). A dynamic and stochastic simulation model, SimHerd, was used to study the effects of mastitis in a herd with 150 cows. Results given the initial in

Which preventive measures against mastitis can increase the technical efficiency of dairy farms?

The aim of this paper was to explore if, and in that case how, various preventive measures against mastitis influenced the whole-farm economic outcome, measured as technical efficiency, of a sample of specialised dairy farms in Sweden. In particular, the paper aimed at analysing whether a change to preventive measures applied by fully efficient farms would be a way for inefficient farms to become

Low-frequency electromagnetic stimulation may lead to regression of Morris hepatoma in buffalo rats

OBJECTIVE: The influence of low-frequency electromagnetic (LF-EM) waves on the processes of carcinogenesis and tumor growth has been the subject of experimental investigations for more than two decades and the results are promising. In parallel, an interesting method of complementary medicine, biophysical-information therapy (BIT) or bioresonance therapy (BRT), which in principle is based on LF-EM

Accuracy of Clinical Tests in Detecting Disk Herniation and Nerve Root Compression in Subjects With Lumbar Radicular Symptoms

Objectives: To investigate the accuracy of 3 commonly used neurodynamic tests (slump test, straight-leg raise [SLR] test, femoral neurodynamic test) and 2 clinical assessments to determine radiculopathy (radiculopathy I, 1 neurologic sign; radiculopathy II, 2 neurologic signs corresponding to 1 specific nerve root) in detecting magnetic resonance imaging (MRI) findings (extrusion, subarticular ner

Serum cathepsin B activity during regression of Morris hepatoma 5123 D

BACKGROUND: Serum cathepsin B activity has been considered a potential marker of tumor progression. We previously demonstrated that low-frequency electromagnetic stimulation (LF EMS), called bioresonance therapy (BRT), may both accelerate and inhibit the growth of transplantable hepatoma (Morris type 5123D), including total tumor regression. The aim of this study was to assess serum cathepsin acti