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Eckart streaming with nonlinear high-order harmonics : An example at gigahertz

Acoustic streaming shows great potential in applications such as bubble dynamics, cell aggregation, and nanosized particle isolation in the biomedical and drug industries. As the acoustic shock distance decreases with the increase of incident frequency, the nonlinear propagation effect will play a role in acoustic streaming, e.g., Eckart (bulk) streaming at a few gigahertz. However, the theory of

Aligned Permanent Magnet Made in Seconds–An In Situ Diffraction Study

The synthesis of a strontium hexaferrite magnet is studied using in situ synchrotron powder X-ray diffraction (PXRD) with a 16-ms time resolution. The precursor material is cold compacted shape-controlled goethite and strontium carbonate. The time evolution of the phases is modeled with sequential Rietveld refinements revealing that strontium hexaferrite forms within seconds at ≈1173 K. Texture an

Anomalous negative magnetoresistance in quantum dot Josephson junctions with Kondo correlations

The interplay between superconductivity and the Kondo effect has stimulated significant interest in condensed matter physics. They compete when their critical temperatures are close and can give rise to a quantum phase transition that can mimic Majorana zero modes. Here, we have fabricated and measured Al-InSb nanowire quantum dot-Al devices. In the Kondo regime, a supercurrent-induced zero-bias c

The role of CT-assessed sarcopenia and visceral adipose tissue in predicting long-term survival in patients undergoing elective endovascular infrarenal aortic repair

OBJECTIVES: To evaluate if ileo-psoas muscle size and visceral adipose tissue (VAT) can predict long-term survival after endovascular aneurysm repair (EVAR). METHODS: Patients who underwent EVAR between 2004 and 2012 in a single centre were included. Total psoas muscle area (TPA), abdominal VAT area, subcutaneous adipose tissue (SAT), and total adipose tissue were measured on the preoperative CT.

Inter domain linker region affects properties of CBM6 in GH5_34 arabinoxylanases and alters oligosaccharide product profile

Understanding the relation between enzyme domain structure and catalytic activity is crucial for optimal engineering of novel enzymes for lignocellulose bioconversion. Xylanases with varying specificities are commonly used to valorise the hemicellulose arabinoxylan (AX), yet characterization of specific arabinoxylanases remain limited. Two homologous GH5_34 arabinoxylanases, HhXyn5A and CtXyn5A, i

Genetic counselling legislation and practice in cancer in EU Member States

Background: Somatic and germline genetic alterations are significant drivers of cancer. Increasing integration of new technologies which profile these alterations requires timely, equitable and high-quality genetic counselling to facilitate accurate diagnoses and informed decision-making by patients and their families in preventive and clinical settings. This article aims to provide an overview of

New injector and storage ring for the MAX-laboratory

In December 1998 the FRN - The Swedish Council for Planning and Coordination of Research - decided to fund a new injector and storage ring for the MAX-laboratory. The system will consist of a 50-MeV linac, a 600-MeV booster synchrotron, and a 600-MeV storage ring for VUV undulator beamlines. The system will replace an old 100-MeV racetrack microtron and will inject the two existing storage rings:

European project to develop a UV/VUV free-electron laser facility on the ELETTRA storage ring

Sincrotrone Trieste, collaborating with various institutions, has recently begun a 3-year project to develop a UV/VUV free-electron laser on the ELETTRA storage ring. The main features and novel technical aspects of the project are described, including the design of the optical cavity and undulator, the electron beam characteristics and a first assessment of the predicted laser performance. Prelim

Head-to-Head Comparison of Tau and Amyloid Positron Emission Tomography Visual Reads for Differential Diagnosis of Neurodegenerative Disorders : An International, Multicenter Study

Objective: We compared the accuracy of amyloid and [18F]Flortaucipir (FTP) tau positron emission tomography (PET) visual reads for distinguishing patients with mild cognitive impairment (MCI) or dementia with fluid biomarker support of Alzheimer's disease (AD). Methods: Participants with FTP-PET, amyloid-PET, and diagnosis of dementia-AD (n = 102), MCI-AD (n = 41), non-AD diseases (n = 76), and co

Acceptable performance of blood biomarker tests of amyloid pathology — recommendations from the Global CEO Initiative on Alzheimer’s Disease

Anti-amyloid treatments for early symptomatic Alzheimer disease have recently become clinically available in some countries, which has greatly increased the need for biomarker confirmation of amyloid pathology. Blood biomarker (BBM) tests for amyloid pathology are more acceptable, accessible and scalable than amyloid PET or cerebrospinal fluid (CSF) tests, but have highly variable levels of perfor

Belimumab concentration measurements using a homologous anti-idiotype immunoassay

Monitoring belimumab concentrations in patients can be a valuable tool for assessing treatment response and for personalizing drug doses. Various assay formats may be used to measure concentrations of therapeutic monoclonal antibodies. A particularly useful format involves the use of anti-idiotype monoclonal antibodies, selected to be highly specific to the antibody of interest. Here, we describe

Utvärdera en alternativ I/O-modul till ABB:s styrsystem

Examensarbetet har utförts på Höganäs AB där stor del av verksamheten drivs av ABB:s styrsystem. Eftersom ABB:s I/O-moduler har lång leveranstid för tillfället men också ett högt inköpspris så sökte företaget alternativ. Det skulle vara lönsamt att testa och analysera alternativ då priserna kan reduceras men också en nödlösning när I/O-moduler går sönder i verksamheten, eller när något nytt behöve

Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic

Objectives: To determine the impact of the COVID-19 pandemic on the incidence rates of infection and islet autoimmunity in children at risk for type 1 diabetes. Methods: 1050 children aged 4 to 7 months with an elevated genetic risk for type 1 diabetes were recruited from Germany, Poland, Sweden, Belgium and the UK. Reported infection episodes and islet autoantibody development were monitored unti

Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles

OBJECTIVE To characterize distinct islet autoantibody profiles preceding stage 3 type 1 diabetes RESEARCH DESIGN AND METHODS The T1DI (Type 1 Diabetes Intelligence) study combined data from 1,845 genetically susceptible prospectively observed children who were positive for at least one islet au-toantibody: insulin autoantibody (IAA), GAD antibody (GADA), or islet antigen 2 antibody (IA-2A). Using

Rationalizing polyp matching criteria in colon capsule endoscopy : an international expert consensus through RAND (modified DELPHI) process

Background: Colon capsule endoscopy (CCE) has gained momentum as an alternative modality for the investigation of the lower gastrointestinal tract. Of the few challenges that remain, the comparison and – eventually – matching of polyps at different timestamps leads to the potential for double reporting and can contribute to false-positive findings and inaccuracies. With the impending artificial in

Hypothermia After Cardiac Arrest in Large Animals (HACA-LA) : Study protocol of a randomized controlled experimental trial

Background: Induced hypothermia post-cardiac arrest is neuroprotective in animal experiments, but few high-quality studies have been performed in larger animals with human-like brains. The neuroprotective effect of postischemic hypothermia has recently been questioned in human trials. Our aim is to investigate whether hypothermia post-cardiac arrest confers a benefit compared to normothermia in la

Between Policy-oriented Criticism and Structural Opposition – Civil Society Advocacy in the Age of Populism

With the wave of right-wing populist parties coming to power and gaining influence in recent years, civil society has been hit by increased ideological resistance from outside. The paper explores how key civil society actors react to policy changes by national governments influenced by right-wing populist parties. The aim is to understand how the rise to power of right-wing populist parties affect

Landscape context and wetland attributes influence wintering waterbirds in important bird and biodiversity areas : implications for conservation and management

Context: The intensification and expansion of human activities have caused profound changes in global wetlands and their associated aquatic bird communities. Understanding the mechanisms that drive the spatial assemblages of wetland birds is important for the development of effective conservation and management strategies. Objectives: The overall objective was to evaluate the influence of wetland

Directly-excited laser-induced thermal grating spectroscopy and thermometry with carbon dioxide vibrational transition

Laser-induced thermal grating spectroscopy (LITGS) has been proved for accurate thermometry and measurement of energy transfer processes in molecules. While electronic transitions are often used for excitation in previous LITGS works, here we report laser-induced thermal gratings formed by direct excitation of CO2 with an infrared (IR) laser at wavelength near 2 μm, with which high signal-to-noise