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OBJECTIVE: To identify how the gp130-signaling cytokine oncostatin M (OSM), acting alone or in concert with IL-1beta or TNFalpha, affects synovial fibroblast expression of genes relevant to inflammation and bone erosion in inflammatory arthritis. METHODS: Synovial fibroblasts (SFs) were isolated from non-arthritic wild type (WT) or OSM receptor deficient (OSMR(-/-)) mice and stimulated with OSM, I
Knowledge about consumer perception and preferences on solid wood, wood-based panels, and wood-based composites is important for product development and marketing. The aim of this study was to identify attributes and associations that people use to describe different types of wood materials and to explore how they relate to preferences. The study involved nine samples that were evaluated with the
We derive Portmanteau tests for a large class of non-linear time series models. This is done by replacing the linear measure of dependence (correlation) with a more general concept. Asymptotic distributions for the test statistics are derived. The methodology is computationally inexpensive, yet more flexible than most similar tests. The tests are evaluated on two different sets of simulated data.
Immunosenescence, the aging of the immune system, is well documented in humans and laboratory models and is known to increase infection risk, morbidity, and mortality among the old. Immunosenescence patterns have recently been unveiled in various free-living populations, but their consequences in the wild have not been explored. We investigated the consequences of immunosenescence in free-living T
Few studies have examined how foraging niche shift of a predator over time cascade down to local prey communities. Here we examine patterns of temporal foraging niche shifts of a generalist predator (yellow catfish, Pelteobagrus fulvidraco) and the abundance of prey communities in a subtropical lake. We predicted that the nature of these interactions would have implications for patterns in diet sh
Post-disaster coordination is an essential aspect to achieve sustainable disaster recovery. However, to date, little attention has been paid to the subject of coordination in disaster recovery in comparison to response coordination. This study is an investigation into the factors affecting coordination for sustainable disaster recovery. It uses the case-study of Eden district Municipality in South
Objectives: To investigate the proposed synergistic teratogenic effect of use of selective serotonin receptor inhibitors (SSRI) together with sedatives or hypnotics, primarily benzodiazepines, during pregnancy. Design: Cohort study of congenital malformations after maternal use of SSRI, sedatives/hypnotics or the combination of the two drug categories. Setting: Swedish national health registers. P
Detailed measurements of the electron performance of the ATLAS detector at the LHC are reported, using decays of the Z, W and J/psi particles. Data collected in 2010 at root s = 7 TeV are used, corresponding to an integrated luminosity of almost 40 pb(-1). The inter-alignment of the inner detector and the electromagnetic calorimeter, the determination of the electron energy scale and resolution, a
Background: Findings from early observational studies have suggested that the intake of dietary fat might be a contributing factor in the etiology of prostate cancer. However, the results from more recent prospective studies do not support this hypothesis, and the possible association between different food sources of fat and prostate cancer risk also remains unclear. Objective: The objectives wer
Isomeric states in the semimagic Sn128-130 isotopes were populated in the fragmentation of a Xe-136 beam on a Be-9 target at an energy of 750 A.MeV. The decay of an isomeric state in Sn-128 at an excitation energy of 4098 keV has been observed. Its half live has been determined to be T-1/2 = 220(30) ns from the time distributions of the delayed gamma rays emitted in its decay. gamma gamma coincide
Recension av Annika Sandén, Missdådare : brott och människoöden i Sverige omkring 1600.
Characteristics of nanoscale materials are often different from the corresponding bulk properties providing new, sometimes unexpected, opportunities for applications. Here we investigate the properties of 8 nm colloidal nanoparticles of MAPbBr3 perovskites and contrast them to the ones of large microcrystallites representing a bulk. X-ray spectroscopies provide an exciton binding energy of 0.32 ±
Popular Abstract in Swedish SVENSK SAMMANFATTNING Huvudsyftet med denna avhandling var att undersöka olika aspekter av självrapporterade sexuella övergrepp under barndom och ungdomstid i en befolkningsstudie med svenska gymnasieelever. Ett av målen var att undersöka livstidsprevalensen för olika typer av sexuella övergrepp och olika övergreppsvariabler samt relationen mellan sexuella övergrepp, köABSTRACT The purpose of this thesis was to investigate aspects of self-reported sexual abuse during childhood and adolescence in a population-based study of Swedish high school students. The aim of this thesis was first to investigate the lifetime prevalence of sexual abuse of varying severity and characteristics as well as the associations between sexual abuse, gender, socio-demographic character
Background: Neuropathy is believed to be a common feature of functional and inflammatory intestinal diseases. Vasoactive intestinal peptide (VIP) is an acknowledged neuroprotective agent in peripheral, including enteric, and central neurons. The proglucagon-like hormones glucagon-like peptide 1 and 2 (GLP1 and GLP2) belong to the secretin/glucagon/ VIP superfamily of peptides and GLP1 and GLP2 rec
Purpose – The purpose of this paper is to present current and ongoing research investigating new ways of working across geographic distances and time within library and information science (LIS). Design/methodology/approach – A total of four studies were conducted focusing on: the design of a virtual research environment (VRE) to facilitate the sharing of data collection instruments among students
In a longstanding debate among economic historians about the role of the peasants and the manors in the agrarian transformation, a variety of qualitative and quantitative indicators have been used, but no one has until now been able to compare the actual production outcomes. In this paper, we investigate the land productivity development for manorial demesnes and peasant farmers, respectively, ove
Newly determined Late Cretaceous Ar-40/Ar-39 ages on megacrystic kaersutite from four lamprophyre dikes, and a U-Pb zircon age on a trachyte, from central and north Westland (New Zealand) are presented. These ages suggest that the intrusion of mafic dikes (88-86 and 69 Ma) was not necessarily restricted to the previously established narrow age range of 80-92 Ma. The younger lamprophyre and trachyt
Abstract in Danish De seneste år er begrebet ‘gentrification’ dukket op i den danske debat. Begrebet har dybe rødder i den geografiske forskning, og det stiller skarpt på de processer, der forandrer byernes geografi, samt diskuterer hvilke sociale og økonomiske konsekvenser forandringerne medfører. I denne artikel undersøger vi fænomenet i forhold til de dramatiske forandringer af Vesterbro i Købe
