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Traumasjukvården har satts under luppen i södra sjukvårdsregionen. Peer review-system för bättre vård

I södra sjukvårdsregionen har ett arbete inletts för att kontinuerligt genomföra sakkunniga granskningar (sk peer review) av traumasjukvården inom regionen. I en första granskningsomgång har sex akutsjukhus deltagit. Resultaten har sammanställts i ett granskningsdokument, som gett upphov till såväl uppmärksamhet och diskussion som konkreta åtgärder på det granskade sjukhuset. Granskningsdokument

Towards ILBC speech coding at lower rates through a new formulation of the start state search

The Internet Low Bit-rate Coder (iLBC) has emerged as a candidate for Voice over Internet Protocol (VoIP) applications. By avoiding the inter-frame coding dependencies endemic to many speech coders such as those based on Code Excited Linear Prediction, iLBC is able to achieve superior robustness to packet loss. In addition to robustness to packet loss, a VoIP codec should possess the agility to ad

Glycemic and risk factor control in type 1 diabetes - Results from 13,612 patients in a national diabetes register

OBJECTIVE - This study was designed to investigate the clinical characteristics of a large type 1 diabetic population and to evaluate the degree of fulfillment of recently updated treatment goals. RESEARCH DESIGN AND METHODS - The Swedish National Diabetes Register was initiated in 1996 as a tool for quality assurance in diabetes care. A1C levels, treatment, and risk factors were analyzed in two c

Amino acid supplementation improves heterologous protein production by Saccharomyces cerevisiae in defined medium

Supplementation of a chemically defined medium with amino acids or succinate to improve heterologous xylanase production by a prototrophic Saccharomyces cerevisiae transformant was investigated. The corresponding xylanase production during growth on ethanol in batch culture and in glucose-limited chemostat culture were quantified, as the native ADH2 promoter regulating xylanase expression was dere

Mortality in childhood-onset type 1 diabetes

OBJECTIVE - To describe the age- and sex-specific mortality in a cohort of young type 1 diabetic patients and to analyze the causes of death with special focus on suicide, accidents, and unexplained deaths. RESEARCH DESIGN AND METHODS - A population-based incident childhood diabetes register, covering onset cases since 1 July 1977, was linked to the Swedish Cause of Death Register up to 31 Decembe

Constraining the Southern Part of the Greenland Ice Sheet since the Last Glacial Maximum from Relative Sea-Level Changes, Cosmogenic Dates and Glacial-Isostatic Adjustment Models

Popular Abstract in Swedish Jordens havsnivå förändras kontinuerligt. I ett längre geologiskt tidsperspektiv styrs förändringarna av processer i jordens inre, men i ett kortare tidsperspektiv spelar yttre processer, såsom tillväxt och avsmältning av inlandsisar, stor roll för havets nivåförändringar. Det grönländska istäcket är idag norra halvklotets enda inlandsis och dess tillväxt och avsmältninNew results are presented from the investigation of relative sea-level changes in the Nanortalik and Qaqortoq-Narsarsuaq areas in SW Greenland from c. 11 000 cal. years BP to the present. Isolation and transgression sequences from seven lakes and seven tidal basins are identified using some of the traditional methods such as stratigraphic description, magnetic susceptibility, saturated induced rem

Scaling up effects in the organic laboratory

A simple, yet safe and effective set of experiments to expose chemistry students to some of the effects that may be encountered when scaling up an organic reaction is described. The exothermic Diels–Alder reaction between maleic anhydride and cyclopentadiene was found to be ideal for our purposes and was performed in small, medium, and large scale for comparison. The observed differences of heat e

Operator Interaction and Optimization in Control Systems

The two themes of this thesis are operator interaction and optimization, primarily with application to complex plants in the process industry. Four important aspects that should be considered in the control system design for such plants are identified; safety, performance, operator interaction and operator acceptance. In particular, operator acceptance is considered as an aspect of major importanc

Varför etiska kommittéer?

Popular Abstract in Swedish Från 1980-talet har etiken diskuterats flitigt i samhället. Det har i samband med detta utvecklats etiska kommittéer. Etiska kommittéer är en typ av organ inom företag, branscher, professioner och andra organisationer som handhar etiska frågor och problem. De etiska kommittéerna fungerar rådgivande i etiska frågor, de kan fastställa etiska regler för en organisation ochThis thesis analyses the development of ethics committees from a sociology of law perspective and a social steerage perspective ("social control"). The main question is: Why are ethics committees established? Institutionalised ethics committee is a rather new phenomenon, which has become widely spread in the last 20 years. The study points out the public ethical debate since the 1980s as a major e

Genetic and Nongenetic Regulation of CAPN10 mRNA Expression in Skeletal Muscle.

The gene encoding calpain-10 (CAPN10) has been identified as a candidate gene for type 2 diabetes. Our aim was to study the impact of genetic (heritability and polymorphisms) and nongenetic (insulin, free fatty acids, and age) factors on CAPN10 mRNA expression in skeletal muscle using two different study designs. Muscle biopsies were obtained before and after hyperinsulinemic-euglycemic clamps fro

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Abstract in Spanish El objeto de este estudio es el Programa Social Agropecuario (PSA) y su interacción con diferentes actores locales en la conformación de las ferias francas en la provincia de Misiones. Estos espacios de comercialización de la pequeña producción agropecuaria comenzaron a organizarse a partir de 1995 y contaron con la participación no sólo del PSA, sino también del gobierno proviThe object of study of this article is the Agriculture Social Program (PSA) and its interaction with diverse local actors in the constitution of the farmers' markets in the province of Misiones, Northeastern Argentina. These markets are social and political spaces for commercialization of small scale agriculture production. The first one emerged in 1995 thanks to the participation of a network of

GABA transporters (GAT-1) in Alzheimer's disease

The presynaptically located gamma-aminobutyric acid (GABA) transporter (GAT-1) was studied in a group of patients with Alzheimer's disease (AD) and in a control group using the GAT-1 selective radioligand [3H]tiagabine. Post mortem brain tissue from frontal cortex, temporal cortex, and caudate nucleus from 18 AD patients and 23 age-matched controls were studied. The binding was saturable (Kd 26 nM