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Objectives: Rituximab (RTX) is a biological treatment used off-label in patients with systemic lupus erythematosus (SLE). This survey aimed to investigate the off-label use of RTX in Europe and compare the characteristics of patients receiving RTX with those receiving conventional therapy. Methods: Data on patients with SLE receiving RTX were taken from the International Registry for Biologics in
Purpose: Patients with a bipolar I disorder (BD-I) manic episode meeting the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), criteria for "with mixed features" have a high incidence of suicide attempts and of anxiety, irritability, and agitation (AIA) symptoms. The aim of this analysis was to explore the relationship between suicidality and AIA symptoms in patients wi
Background: Practices regarding hospitalisation of children at diagnosis of type 1 diabetes vary both within countries and internationally, and high-quality evidence of best practice is scarce. The objective of this study was to close some of the gaps in evidence by comparing two alternative regimens for children diagnosed with type 1 diabetes: hospital-based care and hospital-based home care (HBH
Thylakoids reduce body weight gain and body fat accumulation in rodents. This study investigated whether an enhanced oxidation of dietary fat-derived fatty acids in the intestine contributes to the thylakoid effects. Male Sprague-Dawley rats were fed a high-fat diet with (n = 8) or without thylakoids (n = 8) for 2 wk. Body weight, food intake, and body fat were measured, and intestinal mucosa was
In order to cater for the increasingly complex society several countries have adopted a capabilities-based planning approach, including capability assessments, as part of their preparedness for disasters. Since the number of actors who are dependent on each other is increasing, capability assessments are made based on assumptions of other actors’ capabilities. It is therefore crucial to understand
Description and analysis of Swedish excise duties and Swedish tax policy in field of environmental friendly tax incentives
Flow thinning (FT) is a concept of a traffic routing and protection strategy applicable to communication networks with variable capacity of links. In such networks, the links do not attain their nominal (maximum) capacity simultaneously, so in a typical network state only some links are fully available whereas on each of the remaining links only a fraction of its maximum capacity is usable. Every
The Linked Data approach in data publishing allows the users and their data-driven applications to have broader use cases which encompass various data sources, either publicly available on the Web, or in private repositories. The use of W3C standards in publishing such data enables uniform access across platforms. Transport information today has higher importance to the citizens and society than e
BACKGROUND: There is an increasing amount of reports on IFITM1 (interferon-inducible transmembrane protein 1) in various malignancies. The aim of this study was to examine the expression of IFITM1 and its prognostic significance in gastroesophageal adenocarcinoma.METHODS: Tissue samples were obtained from a consecutive cohort of 174 patients surgically treated between 2006 and 2010 for gastroesoph
