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To teach or not to teach? Junior academics and the teaching-research relationship

The global pressure for excellence has boosted the relevance of the teaching–research relationship. Specifically, the management of teaching and research activities represents an important challenge because of time and resource limitations, especially for junior researchers. The traditionally polarized streams in the literature provide arguments to defend three types of relationship between teachi

Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

Placental malaria can have severe consequences for both mother and child and effective vaccines are lacking. Parasite-infected red blood cells sequester in the placenta through interaction between parasite-expressed protein VAR2CSA and the glycosaminoglycan chondroitin sulfate A (CS) abundantly present in the intervillous space. Here, we report cryo-EM structures of the VAR2CSA ectodomain at up to

Kränkning och upprättelse. En replikation av en rättssociologisk enkätstudie

I rapporten presenteras ett rättssociologiskt forskningsprojekt som haft arbetstiteln ”Replika av en rättssociologisk undersökning om det allmänna rättsmedvetandet och brottsskadeersättningen”. Att projektet är en ”replika” innebär att syftet har varit att göra en uppföljning på ett ursprungligt forskningsprojekt som i det aktuella fallet utgörs av de enkätundersökningar som presterades i avhandli

An Open Source, Automated Tumor Infiltrating Lymphocyte Algorithm for Prognosis in Triple-Negative Breast Cancer

Purpose: Although tumor infiltrating lymphocytes (TIL) assessment has been acknowledged to have both prognostic and predictive importance in triple negative breast cancer (TNBC), it is subject to inter and intra-observer variability that has prevented widespread adoption. Here we constructed a machine-learning based breast cancer TIL scoring approach and validated its prognostic potential in multi

Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden

Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the ass

Hovering flight in hummingbird hawkmoths : Kinematics, wake dynamics and aerodynamic power

Hovering insects are divided into two categories: ‘normal’ hoverers that move the wing symmetrically in a horizontal stroke plane, and those with an inclined stroke plane. Normal hoverers have been suggested to support their weight during both downstroke and upstroke, shedding vortex rings each half-stroke. Insects with an inclined stroke plane should, according to theory, produce flight forces on

Listening effort and fatigue in native and non-native primary school children

Background noise makes listening effortful and may lead to fatigue. This may compromise classroom learning, especially for children with a non-native background. In the current study, we used pupillometry to investigate listening effort and fatigue during listening comprehension under typical (0 dB signal-to-noise ratio [SNR]) and favorable (+10 dB SNR) listening conditions in 63 Swedish primary s

Grinding or shaving?-performance based economic decision support in the manufacturing of gears

This paper describes a case study at an automotive company with the purpose of developing an economically based decision support tool, for strategic decision about whether to chose grinding or shaving as a finishing method in gear manufacturing. In the study different cost models are compared regarding input parameters in alignment with the required input data required to make a decision. With the

Breast softness in patients randomised to postmastectomy breast reconstruction with an expander prosthesis or DIEP flap

Background Objectively measured breast softness in reconstructed breasts and its relation to patients’ subjective satisfactionwith breast softness has not yet been investigated. The aim of this study was to evaluate breast softness in patients 1 yearfollowing delayed breast reconstruction with an expander prosthesis (EP) or deep inferior epigastric perforator (DIEP) fap,using objective and subject

Hierarchical build-up of bio-based nanofibrous materials with tunable metal–organic framework biofunctionality

Multifunctional, light-weight, responsive materials show promise in a range of applications including soft robotics, therapeutic delivery, advanced diagnostics and charge storage. This paper presents a novel, scalable, efficient and sustainable approach for the preparation of cellulose nanofibril-based aerogels via a facile ice-templating, solvent exchange and air-drying procedure, which could rep

Barriers and Facilitators for Implementation of Individualized Fire Safety (IFS) in Sweden

In 2010, the Swedish Civil Contingencies Agency (MSB) announced a “vision zero” of zero fire deaths in Sweden by 2050. Studies into fire deaths have identified that certain risk groups, including but not limited to older people, are overrepresented in fire death statistics in Sweden. The MSB has developed guidelines for how individualised fire safety (IFS) can be implemented in local communities f