Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands : Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules
This article describes the synthesis and characterization of novel cationic five-coordinate Pt(II) complexes containing nitrogen sugar-based ligands. The cytotoxicity of the complexes was evaluated on different cell lines with the expectation that both the coordinative saturation and the sugar moiety cooperate to enhance their biological activity. In fact, the complexes resulted to be more active