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Dairy Consumption, Lactase Persistence, and Mortality Risk in a Cohort From Southern Sweden

Background: Whether high dairy consumption is related to longevity is still unclear, and additional studies of prospective cohorts with high-quality dietary data from populations with wide consumption ranges are needed. Objective: To examine the association between dairy consumption and mortality in a Swedish cohort. Design: Among 26,190 participants (62% females, 45-73 years old) without diabetesBackground: Whether high dairy consumption is related to longevity is still unclear, and additional studies of prospective cohorts with high-quality dietary data from populations with wide consumption ranges are needed. Objective: To examine the association between dairy consumption and mortality in a Swedish cohort. Design: Among 26,190 participants (62% females, 45-73 years old) without diabetes

Corporate ESG reporting quantity, quality and performance : Where to now for environmental policy and practice?

Environmental, social and governance (ESG) issues are driving corporate strategy and performance. However, does this mean more ESG reporting is being done? If so, is the quality of ESG reports improving? And what about ESG performance? In this paper, we examine these three trends in ESG reporting—quantity, quality and corporate ESG performance. With a Swedish multinational corporate focus, we anal

X-Pro : Distributed XDP Proxies Against Botnets of Things

The steadily increasing Internet of Things (IoT) devices are vulnerable to be used as bots to launch distributed-denial-of-service (DDoS) attacks. In this paper, we present X-Pro, a distributed XDP proxy to counteract DDoS attacks. We propose a source-based defense mechanism where proxies located between the IoT devices and the victim performs flow policing on all IoT traffic from a single adminis

A logarithmic bottom boundary layer model for the unsteady and non-uniform swash flow

This paper presents a bottom boundary layer model for the unsteady and non-uniform flow in the swash zone, by extending the momentum integral method so as to include spatial gradients. The developed model is further incorporated into a hydrodynamic model based on the Nonlinear Shallow Water Equations. Two swash zone cases are examined to investigate the effect of the inclusion of spatial gradients

The immobility paradox in Thailand’s southern border provinces

While the general literature analysing mobility patterns in Thailand’s southern border provinces largely indicates insecurity and violence as precipitating factors for migration, such explanations fail to fully explain why the majority of those who migrate do so within the conflict area rather than away from it. Based on fieldwork, this article argues that while a lack of security measures and hig

Regulating the advertising of genetic tests in Europe : a balancing act

Direct-to-consumer (DTC) genetic tests (GT) have provoked criticism over their potential adverse impact on public health. The European Parliament called for a ban on DTC advertising of GT during the debate for the adoption of a European Regulation on in vitro diagnostic medical devices. This proposal, however, was not ultimately retained in the final text. Instead, the regulation includes an artic

Mixed halide perovskites for spectrally stable and high-efficiency blue light-emitting diodes

Bright and efficient blue emission is key to further development of metal halide perovskite light-emitting diodes. Although modifying bromide/chloride composition is straightforward to achieve blue emission, practical implementation of this strategy has been challenging due to poor colour stability and severe photoluminescence quenching. Both detrimental effects become increasingly prominent in pe

Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma : a study of younger patients from the MCL2 and MCL3 clinical trials

Mantle cell lymphoma (MCL) is characterized by marked differences in outcome, emphasizing the need for strong prognostic biomarkers. Here, we explore expression patterns and prognostic relevance of circular RNAs (circRNAs), a group of endogenous non-coding RNA molecules, in MCL. We profiled the circRNA expression landscape using RNA-sequencing and explored the prognostic potential of 40 abundant c

Exploring and comparing definitions of healthy vascular ageing in the population : characteristics and prospective cardiovascular risk

Different methods can be used to define healthy vascular ageing (HVA). In this prospective cohort study, we explored three different definitions in order to provide guidance for which to use. 2718 subjects were included from the Cardiovascular (CV) arm of the Malmö Diet Cancer Study (MDCS; median age 71.9 years, 62.2% females). Three different definitions of HVA were used: HVA-1 (

Online-2D NanoLC-MS for Crude Serum Proteome Profiling : Assessing Sample Preparation Impact on Proteome Composition

Although current LC-MS technology permits scientists to efficiently screen clinical samples in translational research, e.g., steroids, biogenic amines, and even plasma or serum proteomes, in a daily routine, maintaining the balance between throughput and analytical depth is still a limiting factor. A typical approach to enhance the proteome depth is employing offline two-dimensional (2D) fractiona

Despite reductions in muscle mass and muscle strength in adults with CHD, the muscle strength per muscle mass relationship does not differ from controls

Background: Patients with CHD exhibit reduced isometric muscle strength and muscle mass; however, little is known how these parameters relate. Therefore, the aim was to investigate the relation between isometric limb muscle strength and muscle mass for patients in comparison to age- and sex-matched control subjects. Methods: Seventy-four patients (35.6 ± 14.3 years, women n = 22) and 74 matched co

Analysis of extracorporeal photopheresis within the frame of the WAA register

The aim of the study was to investigate safety and if extracorporeal photopheresis (ECP) may change health criteria (HC) and quality of life (QoL). Material and method: 560 patients (33 % women) were treated with ECP for a total of 13,871 procedures during a 17-years period. Mean age was 48 years (±18, range 3−81 years). Self-estimation of QoL was graded: 0 (suicidal) up to 10 (best ever) and HC:

Moving beyond intermediation : How intermediary organizations shape collaboration dynamics in entrepreneurial ecosystems

Recently, increasing attention has been paid to entrepreneurial ecosystems and the process of their formation and function. Researchers have noted the important role that intermediary organizations such as incubators play in connecting various actors within ecosystems. Yet our understanding of this role is limited to a few empirical insights. Using resource dependence and embeddedness as theoretic

Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus

Ribonucleotide reductase (RNR) is an essential enzyme with a complex mechanism of allosteric regulation found in nearly all living organisms. Class I RNRs are composed of two proteins, a large α-subunit (R1) and a smaller β-subunit (R2) that exist as homodimers, that combine to form an active heterotetramer. Aquifex aeolicus is a hyperthermophilic bacterium with an unusual RNR encoding a 346-resid

Low-divergence femtosecond X-ray pulses from a passive plasma lens

Electron and X-ray beams originating from compact laser-wakefield accelerators have very small source sizes that are typically on the micrometre scale. Therefore, the beam divergences are relatively high, which makes it difficult to preserve their high quality during transport to applications. To improve on this, tremendous efforts have been invested in controlling the divergence of the electron b