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Exploring and comparing definitions of healthy vascular ageing in the population : characteristics and prospective cardiovascular risk

Different methods can be used to define healthy vascular ageing (HVA). In this prospective cohort study, we explored three different definitions in order to provide guidance for which to use. 2718 subjects were included from the Cardiovascular (CV) arm of the Malmö Diet Cancer Study (MDCS; median age 71.9 years, 62.2% females). Three different definitions of HVA were used: HVA-1 (

Online-2D NanoLC-MS for Crude Serum Proteome Profiling : Assessing Sample Preparation Impact on Proteome Composition

Although current LC-MS technology permits scientists to efficiently screen clinical samples in translational research, e.g., steroids, biogenic amines, and even plasma or serum proteomes, in a daily routine, maintaining the balance between throughput and analytical depth is still a limiting factor. A typical approach to enhance the proteome depth is employing offline two-dimensional (2D) fractiona

Despite reductions in muscle mass and muscle strength in adults with CHD, the muscle strength per muscle mass relationship does not differ from controls

Background: Patients with CHD exhibit reduced isometric muscle strength and muscle mass; however, little is known how these parameters relate. Therefore, the aim was to investigate the relation between isometric limb muscle strength and muscle mass for patients in comparison to age- and sex-matched control subjects. Methods: Seventy-four patients (35.6 ± 14.3 years, women n = 22) and 74 matched co

Analysis of extracorporeal photopheresis within the frame of the WAA register

The aim of the study was to investigate safety and if extracorporeal photopheresis (ECP) may change health criteria (HC) and quality of life (QoL). Material and method: 560 patients (33 % women) were treated with ECP for a total of 13,871 procedures during a 17-years period. Mean age was 48 years (±18, range 3−81 years). Self-estimation of QoL was graded: 0 (suicidal) up to 10 (best ever) and HC:

Moving beyond intermediation : How intermediary organizations shape collaboration dynamics in entrepreneurial ecosystems

Recently, increasing attention has been paid to entrepreneurial ecosystems and the process of their formation and function. Researchers have noted the important role that intermediary organizations such as incubators play in connecting various actors within ecosystems. Yet our understanding of this role is limited to a few empirical insights. Using resource dependence and embeddedness as theoretic

Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus

Ribonucleotide reductase (RNR) is an essential enzyme with a complex mechanism of allosteric regulation found in nearly all living organisms. Class I RNRs are composed of two proteins, a large α-subunit (R1) and a smaller β-subunit (R2) that exist as homodimers, that combine to form an active heterotetramer. Aquifex aeolicus is a hyperthermophilic bacterium with an unusual RNR encoding a 346-resid

Low-divergence femtosecond X-ray pulses from a passive plasma lens

Electron and X-ray beams originating from compact laser-wakefield accelerators have very small source sizes that are typically on the micrometre scale. Therefore, the beam divergences are relatively high, which makes it difficult to preserve their high quality during transport to applications. To improve on this, tremendous efforts have been invested in controlling the divergence of the electron b

Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery : an international prospective cohort study

We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors

Archaeological Publication Systems : Which route to take? A compass for addressing future development

The recent diffusion of new formats of archaeological publication systems results from ad hoc solutions conceived and realized for serving specific communication needs. These new formats are customized for facilitating the fruition of specific archaeological information and can be tailored and structured for hosting datasets and results. Unlike standard publications, they do not represent the fina

The New Copyright Directive: : Article 17 and copyright limitations – picking two cherries and leaving the rest to spoil? Part I

Evaluation of Article 17(7) and (9) Directive 2019/790 on copyright in the Digital Single Market (DSM Directive) establishing an interface between the obligations of online content-sharing service providers in Article 17(1)-(4) DSM Directive, and the European system of limitations in Article 5 Directive 2001/29 (InfoSoc Directive). Part I, published on the Kluwer Copyright Blog.

Low 30-day mortality and low carbapenem-resistance in a decade of Acinetobacter bacteraemia in South Sweden

Background: The aim of this study was to provide a descriptive account of carbapenem resistance and risk factors for mortality from invasive Acinetobacter infections in the south of Sweden.Methods: Blood isolates with growth of Acinetobacter species between 2010 and 2019 in Skåne county were subtyped using MALDI-TOF and subjected to susceptibility testing against clinically relevant antibiotics. A

Analys och värdering av räddningstjänstens operativa förmåga

Att analysera och värdera räddningstjänstens operativa förmåga är nödvändigt för att tydligt och transparent kunna dimensionera verksamheten. I den här rapporten presenterar vi ett förslag på hur sådana analyser och värderingar kan genomföras med fokus på skydd mot olyckor och kommunal räddningstjänst. Rapporten är framtagen på uppdrag av Malmö stad och Lunds kommun, vilket innebär att den data so

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Plastic extension of Sonata Mexicana by Manuel M. Ponce, 12 paintings with mixed material.