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Incidence and predictors of severe infections in ANCA-associated vasculitis: a population-based cohort study.

Objective. To determine the incidence rate, predictors and outcome of severe infections in a population-based cohort of ANCA-associated vasculitis (AAV). Methods. The study included 325 cases of AAV (152 female) diagnosed from 1997 through 2016 from a defined geographic area in Sweden. All severe infection events (requiring hospitalization and treatment with intravenous antimicrobials) were identi

Using Micro-Scale and Solid Material Data for Modelling Heat Transfer in Stone Wool Composites Under Heat Exposures

Modelling capabilities have drastically improved in the last decade. However, in most of the cases the fire response of building elements is predicted by fitting input material properties to the models in order to match test data. This paper presents models developed to predict the unexposed side temperature of stone wool layered composites with stainless steel or gypsum claddings exposed to sever

SIP laboratory data: frequency-domain versus time-domain

Spectral information from induced polarisation (IP) measurements can be used for several applications as the characterisation of the lithology, the estimation of hydraulic parameters, the localization of contaminated areas and many more.So far, the spectral content has been mainly determined in frequency domain (FD). Due to significant instrumental developments and advanced data processing and inv

Comparison of measuring strategies for frequency-and time-domain induced polarization

Spectral induced polarization (SIP) is an increasingly interesting technique for field investigations since it can provide valuable information on the properties of the subsurface deposits or groundwater units. Field measurements can be carried out in the frequency domain (FD) or in the time domain (TD) but should lead to the same spectral subsurface description. IP measurements are superimposed b

Association of incident fragility fractures in patients hospitalised due to unexplained syncope and orthostatic hypotension

Background Fragility fractures are caused by low-energy insults such as falls from standing height or less and pose a growing health challenge as their incidence rises with increasing age. Impaired orthostatic blood pressure response and a number of cardiovascular biomarkers have been previously identified as risk factors for fractures. It is likely that severe episodes of syncope and orthostatic

Hairy cell leukemia and COVID-19 adaptation of treatment guidelines

Standard treatment options in classic HCL (cHCL) result in high response rates and near normal life expectancy. However, the disease itself and the recommended standard treatment are associated with profound and prolonged immunosuppression, increasing susceptibility to infections and the risk for a severe course of COVID-19. The Hairy Cell Leukemia Foundation (HCLF) has recently convened experts a

A Scoping Review of Constructs Measured Following Intervention for School Refusal : Are We Measuring Up?

Reviews of the effectiveness of interventions for school refusal (SR) rely upon well-conducted primary studies. Currently there are no guidelines for those conducting primary studies about the measurement of outcome following intervention for SR. Most people would agree that it is important to measure school attendance as an outcome but there has been little discussion about other constructs that

HERFD-XANES probes of electronic structures of ironII/IIIcarbene complexes

Iron centeredN-heterocyclic carbene (Fe-NHC) complexes have shown long-lived excited states with charge transfer character useful for light harvesting applications. Understanding the nature of the metal-ligand bond is of fundamental importance to rationally tailor the properties of transition metal complexes. The high-energy-resolution fluorescence detected X-ray absorption near edge structure (HE

Nowcasting (short-term forecasting) of influenza epidemics in local settings, Sweden, 2008–2019

The timing of influenza case incidence during epidemics can differ between regions within nations and states. We conducted a prospective 10-year evaluation (January 2008–February 2019) of a local influenza nowcasting (short-term forecasting) method in 3 urban counties in Sweden with independent public health administrations by using routine health information system data. Detection-of-epidemic-sta

Multilocus and morphological analysis of south-eastern Iberian Wall lizards (Squamata, Podarcis)

The phylogenetic relationships among the wall lizards of the Podarcis hispanicus complex that inhabit the south-east (SE) of the Iberian Peninsula and other lineages of the complex remain unclear. In this study, four mitochondrial and two nuclear markers were used to study genetic relationships within this complex. The phylogenetic analyses based on mtDNA gene trees constructed with ML and BI, and

Calibrating the Wildfire Decision Model using hybrid choice modelling

Wildfire occurrences is creating serious challenges for fire and emergency response services and a diverse range of communities around the world due to the increment of the occurrence of these disasters. As such, understanding the physical and social dynamics characterizing wildfires events is paramount to reduce the risk of these natural disasters. As such, one of the main challenges is to unders