This thesis investigates Nestlé’s impunity for aiding and abetting forms of child labour in Côte d’Ivoire through analysing the landmark case Doe v. Nestlé. By employing a qualitative content analysis, this study disseminates the nearly two-decade court battle of oral arguments before the Supreme Court, amicus briefs from interested third parties, court rulings, as well as an interview with the le

High-performance mobile GPUs (Graphics Processing Units) handle complex graphics workloads, significantly benefiting the development of mobile gaming. However, the growing demand for enhanced GPU performance presents a major challenge in controlling power consumption, where memory usage plays a critical role. This thesis focuses on exploring methods to reduce power consumption in GPU Tile Buffer m

This chapter analyses the role that 'ordre public' and morality exceptions can play in the granting of patents on inventions in the field of human germline editing and the consequences of this policy option. In order to provide the context for such an analysis, the chapter will, first, provide an overview of the current patent landscape for relevant genome editing technologies, drawing attention t

The processes responsible for the formation of Earth's most conspicuous diversity pattern, the latitudinal diversity gradient (LDG), remain unexplored for many clades in the Tree of Life. Here, we present a densely sampled and dated molecular phylogeny for the most speciose clade of damselflies worldwide (Odonata: Coenagrionoidea) and investigate the role of time, macroevolutionary processes, and

Background This study aimed to describe the initial treatment of clubfoot deformity in Sweden using a national cohort. Secondarily we aimed to analyse the results of the initial treatment in relation to foot severity and additional diseases. Methods A national register, the Swedish Pediatric Orthopedic Quality Register, was used to extract data on children born with clubfoot in 2016–2019. Children

The interplay between aging and immune system deterioration presents a formidable challenge to human health, especially in the context of a globally aging population. Aging is associated with a decline in the body’s ability to combat infections and an increased risk of various diseases, underlining the importance of rejuvenating the immune system as a strategy for promoting healthier aging. In iss

This chapter presents an interpretation of Bernard Williams’s significant and substantial contributions on the topic of free will and moral responsibility. Williams’s fundamental objective, it is argued, is to vindicate moral responsibility by way of freeing it from distortions and misrepresentations imposed on it by “the morality system.” Although his earlier work is primarily concerned with the

Safe and clean drinking water delivery is challenged by climate change, as elevated temperatures can promote the growth of pathogens and other detrimental microorganisms. The microbial processes underlying drinking water production in slow sand filters (SSFs) are largely uncharacterized, limiting the possibilities of improving this technology. Periodical clogging, potentially by microbes, disrupts

This study examines spermatogonial numbers in testicular samples from 43 prepubertal patients undergoing haematopoietic stem cell transplantation (HSCT). High-dose chemotherapy and/or radiation during HSCT can impact spermatogenesis requiring fertility preservation. Results show that 49% of patients have decreased and 19% severely depleted spermatogonial pool prior to HSCT. Patients with Fanconi a

BakgrundLångvarig behandling med opioida läkemedel, här definierat som> 3 månader, på indikation långvarig icke-malign smärta är vanligt förekommande i smärtvården. Vid undersökningar i Lund och Linköping har noterats att ungefär en tredjedel av populationen vid smärtklinikerna exponeras för opioidbehandling, trots avsaknad av evidens och samtidigt väl kända risker med behandlingen. Nedtrappning a

Introduction: Galectin-3 is a pro-fibrotic β-galactoside binding lectin highly expressed in fibrotic liver and implicated in hepatic fibrosis. Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human KD = 25 nM; rabbit KD = 12 nM) and high oral bioavailability in rabbits and man. In this study the efficacy of

Context. The light element (anti-)correlations shown by globular clusters (GCs) are the main spectroscopic signature of multiple stellar populations. These internal abundance variations provide us with fundamental constraints on the formation mechanism of stellar clusters. Aims. Using Gaia-ESO, the largest and most homogeneous survey of open clusters (OCs), we intend to check whether these stellar

The antibody response to SARS-CoV-2 shows biased immunoglobulin heavy chain variable (IGHV) gene usage, allowing definition of genetic signatures for some classes of neutralizing antibodies. We investigated IGHV gene usage frequencies by sorting spike-specific single memory B cells from individuals infected with SARS-CoV-2 early in the pandemic. From two study participants and 703 spike-specific B

Sloth - one of the deadly sins in our life - is here connected to waste handling in historical, recent, and future times. The text is structured in three themes: how waste is hidden and forgotten; waste kept at distance; waste, technology, and shame. It ends with reflections on concepts such as the old deadly sins, rigid as they may be, is worth defending and if they still might speak to a modern Someone who throws away their rubbish on a street-corner or in a ditch is guilty of sloth. This may appear harmless, but seen through the lens of waste management, sloth soon develops into a deadly sin that harms other people’s lives and health. Hiding and forgetting waste has always been a practice with potentially disastrous consequences; buried containers full of toxins will eventually start to

This entry is intended to provide the reader with an overview of the central themes and arguments found in David Hume's (1711–1776) contributions to the philosophy of religion. The topics covered include the argument from design and the cosmological argument; the problem of evil; miracles and revealed religion; the natural history of religion; and Hume's philosophy of irreligion and atheism.

More and more cities are being marketed as green. Malmö has since the late 90ies transformed from a city in great economic downturn to being internationally known for its green profile, attracting companies, tourists and professional visitors. Despite its reputation of being the city of parks Malmö has the second to least green space per person in all of Sweden’s urban areas, and it’s shrinking. T