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WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in

Trust-Based Fast Authentication for Multiowner Wireless Networks

In multiowner wireless networks, access points (APs) are owned and operated by different administrations, leading to significant authentication delays during handoff between APs. We propose to exploit the trust between the owners of neighboring APs for reducing the authentication delay. In the proposed authentication scheme, neighboring APs that trust each other share the security key for the visi

Depression in the Lundby Study 1947-1997 Incidence, course and risk-factors

Abstract The aims of this thesis were to describe methodological problems, incidence and course of depressive disorders as well as possible risk factors for depression within the framework of the Lundby Study. The Lundby population was investigated in 1947, 1957, 1972 and 1997. In 1947 the population consisted of 2550 subjects and in 1957, 1013 were added. The total population consists of 3563 s

Rosiglitazone Enhances Apolipoprotein M (Apom) Expression in Rat's Liver.

Apolipoprotein M (APOM) has been suggested as a vasculoprotective constituent of high density lipoprotein (HDL), which plays a crucial role behind the mechanism of HDL-mediated anti-atherosclerosis. Previous studies demonstrated that insulin resistance could associate with decreased APOM expressions. In agreement with our previous reports, here, we further confirmed that the insulin sensitivity wa

Raphidicyrtis trichosporella new to Sweden.

Rhaphidicyrtis trichosporella (Nyl.) Vain. is reported here as new to Sweden from five sites in the southernmost part of the country, two in the province of Skåne and three in Småland. All sites are deciduous woodlands of different composition, but most likely with a long ecological continuity. Two records are from scaling bark of Alnus glutinosa in Alnus swamps, two from hard and smooth bark of F

Relationship between condensed tannin structures and their ability to precipitate feed proteins in the rumen

BACKGROUND Tannins can bind to and precipitate protein by forming insoluble complexes resistant to fermentation and with a positive effect on protein utilisation by ruminants. Three protein types, Rubisco, rapeseed protein and bovine serum albumin (a single high-molecular weight protein), were used to test the effects of increasing concentrations of structurally different condensed tannins on prot

The difference between living biblically and just imagining it: A study on experiential-based learning among Swedish adolescents

As an assignment in their course of Worldwide Religions, a group of Swedish High School pupils followed 12 biblical rules for two weeks, while another group from the same school just imagined the experience. Groups were asked to reflect and write down either how it was (experience) or how it would have been (imagine) to follow the rules. By applying a semantic test, based on a Latent Semantic Anal

Formation of trioctylamine from octylamine on Au(111)

The adsorption of octylamine on Au(111) under ultrahigh vacuum conditions is investigated. The molecules surprisingly undergo a thermally activated chemical reaction, resulting in formation of trioctylamine as confirmed both by X-ray photoelectron spectroscopy (XPS) and by comparison to the scanning tunneling microscopy (STM) signature of trioctylamine deposited directly onto the surface.

"The Logic of Care" - Parents' perceptions of the educational process when a child is newly diagnosed with type 1 diabetes

Background: The number of new cases of type 1 diabetes mellitus (T1DM) has increased substantially in recent years and it is now one of the most common long-term endocrine disorders in childhood. In Sweden the child and family are hospitalised in accordance with the national guidelines for one to two weeks at diagnosis. The purpose of this study was to describe parents' perceptions of the educatio

Physical-environment Qualities of Supported-housing Facilities for People with Severe Mental Illness

The physical environment of supported-housing facilities (SHF) for people with severe mental illness has mainly been investigated in terms of neighborhood quality and community integration, largely neglecting the design of housing attributes. This study investigated whether SHFs with high and low levels of physical-environment quality differed in their support of users' (residents and staff) needs

Commercial potato protein concentrate as a novel source for thermoformed bio-based plastic films with unusual polymerisation and tensile properties

Commercial potato protein concentrate (PPC) was investigated as a source of thermoformed bio-based plastic film. Pressing temperatures of 100 to 190 degrees C with 15 to 25% glycerol were used to form PPC films. The shape of the tensile stress-strain curve in thermoformed PPC was controlled by glycerol level and was independent of processing temperature. Tensile testing revealed that elongation at

Climatic niche divergence or conservatism? Environmental niches and range limits in ecologically similar damselflies

The factors that determine species' range limits are of central interest to biologists. One particularly interesting group comprises odonates (dragonflies and damselflies), which show large differences in secondary sexual traits and respond quickly to climatic factors, but often have minor interspecific niche differences, challenging models of niche-based species coexistence. We quantified the env

A note on "A combinatorial proof of associativity of Ore extensions"

Nystedt recently gave a combinatorial proof of the fact that Ore extensions are associative. As part of it he proves that two sets of strings are identical, using a counting argument. We show that the equality of the sets can be proven directly. (C) 2013 Elsevier B.V. All rights reserved.

Evolution of increased phenotypic diversity enhances population performance by reducing sexual harassment in damselflies.

The effect of evolutionary changes in traits and phenotypic/genetic diversity on ecological dynamics has received much theoretical attention; however, the mechanisms and ecological consequences are usually unknown. Female-limited colour polymorphism in damselflies is a counter-adaptation to male mating harassment, and thus, is expected to alter population dynamics through relaxing sexual conflict.

On the Value of Double Vision

This article is, first, an analysis of arguments that have been leveled against systematic empirical research in psychoanalysis. The arguments are basically two: It cannot uncover unobservable processes, and it cannot account for the uniqueness of the psychoanalytic dyad. Therefore, systematic empirical research is said to be incompatible with basic tenets of psychoanalysis. Both arguments are ref

Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study

Background: Disseminated tumour cells (DTCs) in the bone marrow of patients with breast cancer have been identified as an independent predictor of poor prognosis in patients with non-metastatic disease. This prospective study aimed to evaluate the presence and prognostic value of DTCs in the bone marrow of female patients with primary breast cancer. Methods: Between 1999 and 2003, bone marrow aspi