The saints’ Lives written by Kyrillos (Cyril) of Skythopolis form a centrepiece in Greek hagiography, not least through the two central Lives of Euthymios and Sabas, respectively. The occurrence of lions in the Kyrillos’ narrative has been noted before, but not with respect to their eschatological and symbolic function, especially in attaching the performance of the saints to landscape and wildern

Abstract in Thaiชาวจีนจำนวนมากเดินทางเข้ามายังเดลี-เมดานในช่วงศตวรรษที่ 19 ในฐานะแรงงานสัญญาจ้างเพื่อพัฒนาเขตเกษตรกรรมของดัตช์บนเกาะสุมาตราโดยเฉพาะบริเวณตะวันออกของสุมาตราเหนือครอบคลุมพื้นที่ของเดลี เซอดัง (Deli-Serdang) และเมืองเมดาน (Medan) ในปัจจุบัน พื้นที่ดังกล่าวถูกพัฒนาขึ้นให้กลายเป็นพื้นที่เกษตรกรรมสมัยใหม่ มีการเพาะปลูกพืชหลายชนิด โดยพืชเศรษฐกิจที่สำคัญที่สุดในพื้นที่ขณะนั้น คือ ใบยาสูบ ซIn the 19th Century, Deli-Medan received a large number of Chinese migrants. Most of them worked as labourers in Dutch agricultural plantations on the east coast of Sumatra, extending from Deli-Serdang to Medan. The agricultural products, such as tobacco, were intentionally developed and eventually became the most exportedproducts of Sumatra. As these economic activities paved the way for economic

Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome Consortium/The Cancer Genome Atlas Pan-Cancer Analysis of Whole Genomes Consortium, which aggregated whole-genome sequencing data from 2,658 cancers across 38 tumor types, we performed a multidimensional, integrated characterization of mitochondrial genomes and relate

Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we characterized mutational signatures using 84,729,690 somatic mutations from 4,645 who

Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and-for a subset-whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential viral pathogens using a consensus approach that integrated three independent pipelines. Viruses were detected in 382 genome and 68 transcriptome dat

Population ageing is a fact of all advanced economies. Fewer people are born all the while current members live longer. The support which old people have come to depend on, for example through elderly care and pensions, thus becomes increasingly expensive. This accentuates an assurance problem. Although it has been and still is the case that the young are willing to support the currently old, this

Two competing predictions regarding highly dispersible clonal plants, such as bryophytes, expect levels of genetic diversity to either increase or decrease over time following a disturbance that opens habitat for colonization. Following up on previous research that found higher levels of genetic variation in bryophytes from relatively undisturbed forest sites, we examined unisexual, haploid specie

Surtsey island was formed in a volcanic eruption south of Iceland in 1963 – 1967 and has since then been protected and monitored by scientists. It is the youngest island in the Vestmannaeyjar archipelago. The archipelago is of volcanic origin, but the other islands are ca. 5 000 to 40 000 yrs old. The first two moss species were found on Surtsey as early as 1967 and several new bryophyte species w

Background: Treatment of common bile duct (CBD) stones after Roux-en-Y gastric bypass (RYGB) poses a particular challenge given the altered anatomy and inability to perform a standard endoscopic retrograde cholangiogram (ERC). The optimal treatment strategy for intraoperatively encountered CBD stones in post-RYGB patients has not been established. Objectives: To compare outcomes following laparosc

A higher intake of gluten during childhood is associated with increased risk of celiac disease, and the incidence of celiac disease peaks shortly after the time point when associations with higher gluten intake during the second and third year of life occur. Additional environmental factors are most likely necessary for celiac disease to develop. It is hypothesized that gastrointestinal infections

Background: Moderate-to-severe hemophilia B is treated with lifelong, continuous coagulation factor IX replacement to prevent bleeding. Gene therapy for hemophilia B aims to establish sustained factor IX activity, thereby protecting against bleeding without burdensome factor IX replacement. Methods: In this open-label, phase 3 study, after a lead-in period (≥6 months) of factor IX prophylaxis, we

The ecological effects of mass-flowering crops on pollinator abundance and species richness of neighbouring habitats are well established, yet the potential evolutionary consequences remain unclear. We studied effects of proximity to a mass-flowering crop on the pollination of local co-flowering plants and on patterns of natural selection on a pollination-generalised plant on the Tibetan Plateau.

Objectives: In Sweden, pneumococcal serotype distribution in adults with community-acquired pneumonia (CAP) and potential coverage of currently licensed pneumococcal conjugate vaccines (PCVs) is unknown. Methods: During 2016–2018, patients aged ≥18 years hospitalized with radiologically confirmed (RAD+) CAP were enrolled at Skåne University Hospital in a study on the etiology of CAP in Sweden (ECA

Impulsive noise is one of the most challenging forms of interference in an underwater acoustic environment. In this paper, we present an underwater acoustic channel deconvolution method based on a sparse representation framework. The application of the method enables a channel impulse response reconstruction that is robust to impulsive noise. By exploiting the inherent structure in the channel res

BackgroundPrevious research has emphasized the high prevalence and far-reaching consequences of violations of ethical principles in patient care.AimTo study the extent of violations perceived by healthcare professionals in Swedish adult psychiatric care.MethodsOnline survey among 2,538 mental health professionals. A revised version of Transgressions of Ethical Principles in Health Care Questionnai

In his ‘Provocation in Philosophy and Art’ Dan Egonsson argues that provocation is integral to Socrates’ way of doing philosophy both when aiming for (the interlocutor’s) personal moral development and as an instrument for societal change, and that provocation in art differs significantly from its Socratic counterpart. Morally dubious provocation in art can, however, Egonsson argues be justified o