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Long-term outcome after ischemic stroke in relation to comorbidity – An observational study from the Swedish Stroke Register (Riksstroke)

Purpose: Comorbidity in stroke is common, but comprehensive reports are sparse. We describe prevalence of comorbidity and the prognostic impact on mortality and functional outcome in a large national ischemic stroke cohort. Methods: We used outcome data from a long-term follow-up survey conducted in 2016 by the Swedish Stroke Register (Riksstroke). Those included in the study were 11 775 pre-strok

Dealing with accountability in project selection

The purpose of this study is to present a framework to assess how project individuals deal with accountability in project selection. The framework is designed based on project selection and accountability literature and empirical data. Empirical data was collected through semi-structured interviews with project individuals working at organizations operating in information technology and working wi

Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells

Human immunodeficiency virus type 1-based lentivirus vectors containing the green fluorescent protein (GFP) gene were used to transduce murine Lin(-) c-kit(+) Sca1(+) primitive hematopoietic progenitor cells. Following transduction, the cells were plated into hematopoietic progenitor cell assays in methylcellulose and the colonies were scored for GFP positivity. After incubation for 20 h, lentivir

Sweden

Industrial relations in Sweden are part of the Nordic legal tradition. This is characterised by labour law which is largely semi-discretionary law and collective agreements are the most important instrument for regulation of the labour market; these agreements offer a high degree of coverage. Trade unions are well organised and play a central role in the labour law system. During the past 25 years

Gastroduodenal morphology and related symptoms in chronic alcoholics

Twenty-four chronic alcoholics admitted to hospital for detoxification after a drinking spree were examined by upper gastrointestinal endoscopy. Biopsy specimens were taken from corpus/fundus, antrum and duodenum for tissue histology (eosin stain). From the duodenum villus index and ultrastructure (scanning electron microscopy, SEM) were also performed. As a control group 12 subjectively healthy n

Metabolism of chylomicron phosphatidylinositol in the rat : fate in vivo and hydrolysis with lipoprotein lipase and hepatic lipase in vitro

Phosphatidylinositol (PI), mainly stearoyl-arachidonyl PI, occurs as a minor phospholipid constituent in both chyle and plasma lipoproteins. The kinetics and the pathway by which plasma and chyle PI is metabolized have not been investigated. The role of lipoprotein PI in the supply of arachidonic acid (20:4) and inositol lipid components to different tissues is thus unknown. In this study we exami

Primary surgery in ovarian cancer : current opinions

There have been no controlled clinical trials supporting the use of primary cytoreductive surgery. The question remains as to whether the observed survival benefits for patients subjected to primary cytoreductive surgery are an effect of surgical skill or tumour biology. The proponents of tumour biology claim that cytoreductive surgery is a selective procedure, choosing patients with better progno

A randomized, multicenter study comparing the efficacy and tolerability of tropisetron, a new 5-HT3 receptor antagonist, with a metoclopramide-containing antiemetic cocktail in the prevention of cisplatin-induced emesis

BACKGROUND: Chemotherapy-induced emesis is one of the most disturbing side effects in cancer therapy. Thus, antiemetic treatment is a mandatory adjunct in emetogenic chemotherapy.METHODS: Tropisetron (Navoban, Sandoz Pharma Ltd., Basel, Switzerland), a new 5-HT3 receptor antagonist, was compared in a randomized multicenter trial with a high-dose metoclopramide-dexamethasone cocktail for the preven

Event-shape and multiplicity dependence of freeze-out radii in pp collisions at √s = 7 TeV

Two-particle correlations in high-energy collision experiments enable the extraction of particle source radii by using the Bose-Einstein enhancement of pion production at low relative momentum q ∝ 1/R. It was previously observed that in pp collisions at s = 7TeV the average pair transverse momentum kT range of such analyses is limited due to large background correlations which were attributed to m

Nursing and training of pigs used in renal transplantation studies

The pig is commonly used in renal transplantation studies since the porcine kidney resembles the human kidney. To meet the requirements of intense caretaking and examination without stress, a 2-week socialisation and training programme was developed. Conventional cross-breed pigs (n = 36) with high health status were trained for 15 min/day in a four-step training programme before kidney transplant

The Effect of Canthotomy on Blood Perfusion During the Repair of Lower Eyelid Defects

PURPOSE: Canthotomy is frequently used to mobilize extra tissue when repairing larger lower eyelid defects. The aim of this study was to explore the effect of canthotomy on blood perfusion and oxygen tension.METHODS: Eight pigs underwent a wedge resection of the lower eyelid and canthotomy (with cantholysis involving the lateral palpebral artery). The wedge resection was performed 8, 6, and 4 mm f

Measuring originality in science

Originality has self-evident importance for science, but objectively measuring originality poses a formidable challenge. We conceptualise originality as the degree to which a scientific discovery provides subsequent studies with unique knowledge that is not available from previous studies. Accordingly, we operationalise a new measure of originality for individual scientific papers building on the

Social protection for workers outside the traditional employment contract – a Swedish example

This chapter contains an outline of the Swedish social security system with a focus on sickness benefits in the social security and unemployment insurance. The Swedish legislator’s ambition has been to create parity between different forms of employment as well as between those who are self-employed and those who operate in different company structures. Legislative amendments in this area have mai

Efterord

Efterord till nyutgåva av Axel Wallengrens (Falstff, fakirs) ofullbordade bok "Tripp till världens ända". Inkluderar kort biografi över Wallengren samt redogörelse för manuskriptets tillkomst och tidigare publicering.

Early-onset pancreatic cancer : a population-based study using the SEER registry

Background: Early-onset pancreatic cancer (< 50 years, EOPC) is uncommon and limited data exist on clinical presentation and long-term survival. The aim of this study was to compare outcomes between patients with EOPC and those with later-onset pancreatic cancer (≥ 50 years, LOPC) using a large population-based cohort. Methods: The Surveillance, Epidemiology, and End Results (SEER) database was qu

Measurement of the production of charm jets tagged with D0 mesons in pp collisions at √s=7 TeV

The production of charm jets in proton-proton collisions at a center-of-mass energy of s=7 TeV was measured with the ALICE detector at the CERN Large Hadron Collider. The measurement is based on a data sample corresponding to a total integrated luminosity of 6.23 nb−1, collected using a minimum-bias trigger. Charm jets are identified by the presence of a D0 meson among their constituents. The D0 m