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High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden
Objective. To search for primary hyperaldosteronism (PHA) among previously known hypertensive patients in primary care, using the aldosterone/renin ratio (ARR), and to evaluate clinical and biochemical characteristics in patients with high or normal ratio. Design. Patient survey study. Setting and subjects. The study population was recruited by written invitation among hypertensive patients in two
Human CO-binding protein selectively interacts with Neisseria gonorrhoeae and results in species-specific infection
Neisseria gonorrhoeae is the causative agent of gonorrhea, a disease that is restricted to humans. Complement forms a key arm of the innate immune system that combats gonococcal infections. N. gonorrhoeae uses its outer membrane porin (Por) molecules to bind the classical pathway of complement down-regulatory protein C4b-binding protein (C4bp) to evade killing by human complement. Strains of N. go
Accelerator vacuum systems at MAX-lab
The paper describes briefly the present and future accelerator vacuum systems at MAX-lab, a national laboratory for synchrotron radiation and nuclear physics in Lund, Sweden. The present accelerator systems at MAX-lab, with the 500 MeV MAX I, the 1.5 GeV MAX II, and the 700 MeV MAX III storage rings, contain a variety of different vacuum pumps. In all three storage rings ion pumps and Titanium Sub
Noun phrase morphology in Swedish-speaking children with specific language impairment
Children with specific language impairment (SLI) are often described as having great difficulty with grammatical morphology, but most studies have focused only on these childrens use of verb morphology. In this study, we examined the use of noun phrase (NP) morphology by preschool-age children with SLI who are acquiring Swedish. Relative to typically developing same-age peers and younger peers mat
Promiscuity in sand lizards (Lacerta agilis) and adder snakes (Vipera berus): Causes and consequences
We review postcopulatory phenomena in the Swedish sand lizard (Lacerta agilis) and adder (Vipera berus), and in particular, links between female promiscuity, determinants of paternity, and offspring viability. In both species, females mate multiply and exhibit a positive relationship between the number of partners and offspring viability. We conclude that this relationship is most likely the resul
Older Men with Low Serum Estradiol and High Serum SHBG Have an Increased Risk of Fractures
Recrystallization of waxy maize starch during manufacturing of starch microspheres for drug delivery: Influence of excipients
The formation of ordered structure, such as crystallites, in starch was studied by means of differential scanning calorimetry (DSC). The influence of time/temperature treatment and additives such as polyethylene glycol (PEG), bovine serum albumin (BSA) and a carbonate buffer on the formation was investigated. The experiments were planned with a CCC (Central Composite Circumscribed) design. For all
Contractility of the myometrium; the rationale for pharmacological intervention in preterm labour
Statistical downscaling and scenario construction of precipitation in Scania, southern Sweden
Statistical downscaling models for precipitation in Scania, southern Sweden, have been developed and applied to calculate the changes in the future Scanian precipitation climate due to projected changes in the atmospheric composition. The models are based on multiple linear regression, linking large-scale predictors at monthly time resolution to regional statistics of daily precipitation on a mont
Expression of serotonin receptors and role of serotonin in human prostate cancer tissue and cell lines.
Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins.
Non-pylori Helicobacteraceae in the upper digestive tract of asymptomatic venezuelan subjects: Detection of helicobacter cetorum-like and candidatus Wolinella africanus-like DNA
Background: The spectrum of human non-pylori Helicobacter infections is expanding, with species such as H. heilmannii and H. felis occasionally being associated with gastritis. However, the existence of non-pylori Helicobacter colonization in asymptomatic subjects has not been evaluated. The aim of this study was to investigate whether Helicobacter species other than pylori are present in the uppe
Protein self-association in solution: the bovine beta-lactoglobulin dimer and octamer
We have used proton magnetic relaxation dispersion (MRD) to study the self-association of bovine ß-lactoglobulin variant A (BLG-A) as a function of temperature at pH 4.7 (dimer–octamer equilibrium) and as a function of NaCl concentration at pH 2.5 (monomer–dimer equilibrium). The MRD method identifies coexisting oligomers from their rotational correlation times and determines their relative popula
Bacterial vaginosis - Transmission, role in genital tract infection and pregnancy outcome: An enigma
Larsson PG, Bergstrom M. Forsum U, Jacobsson B, Strand A, Wolner-Hanssen P Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma. APMIS 2005; 113:233-45. Whether bacterial vaginosis (BV) is acquired from an endogenous or an exogenous source is subject to controversy Despite findings of an association between sexual behaviour and BV some data indicate t
Comparison of potato amylopectin starches and potato starches - influence of year and variety
Starches from three potato varieties and their respective transformants producing amylopectin starch were studied over a period of 3 years. The gelatinisation, swelling and dispersion properties were studied using differential scanning calorimetry (DSC), X-ray diffraction, swelling capacity measurements and a Brabender Viscograph. The potato amylopectin starches (PAP) exhibited higher endothermic
Protein C levels can be forecasted by global haemostatic tests in critically ill patients and predict long-term survival.
Influence of formation path on the CH2BrCl2+ dissociation dynamics
To get further insight into the CH2BrCl site-selective fragmentation previously observed upon inner-shell ionization, we have performed high-resolution Br 3d and Cl 2p Auger and spin-orbit resolved Br 3d Auger spectra, and studied the dissociation properties of the CH2BrCl2+ dication formed at threshold by means of threshold electron pair-ion coincidence measurements. The key point is that the ori
Modeling the in-flight events during metal spray forming
In this work, the in-flight events occurring during deposition over a rotating substrate were modeled. The calculations were performed by solving the momentum and enthalpy equations for the gas. A Lagrangian approach was used to obtain the trajectories and thermal history of the droplets. A modified heat capacity model was used to simulate the release of latent heat due to the solidification of th
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
The iron-regulatory hormone hepcidin has been proposed as the mediator of anemia of inflammation (AI). We examined the acute and chronic effects of hepcidin in the mouse. Injections of human hepcidin (50 microg/mouse), but not of its diluent, induced hypoferremia within 4 hours. To examine the chronic effects of hepcidin, we implanted either tumor xenografts engineered to overexpress human hepcidi