Celiac disease is associated with the HLA-DR3-DQA1*05:01-DQB1*02:01 and DR4-DQA1*03:01-DQB1*03:02 haplotypes. In addition, there are currently over 40 non-HLA loci associated with celiac disease. This study extends previous analyses on different HLA haplotypes in celiac disease using next generation targeted sequencing. Included were 143 patients with celiac disease and 135 non-celiac disease cont

Measurements of the electroweak production of a W boson in association with two jets at high dijet invariant mass are performed using s= 7 and 8 TeV proton–proton collision data produced by the Large Hadron Collider, corresponding respectively to 4.7 and 20.2 fb- 1 of integrated luminosity collected by the ATLAS detector. The measurements are sensitive to the production of a W boson via a triple-g

The production of beauty hadrons was measured via semi-leptonic decays at mid-rapidity with the ALICE detector at the LHC in the transverse momentum interval 1

Software engineers working in large projects must navigate complex information landscapes. Change Impact Analysis (CIA) is a task that relies on engineers' successful information seeking in databases storing, e.g., source code, requirements, design descriptions, and test case specifications. Several previous approaches to support information seeking are task-specific, thus understanding engineers'

Malaria is a climate sensitive disease that is causing rampant deaths in sub-Saharan Africa (SSA) and its impact is expected to worsen under climate change. Thus, pre-emptive policies for future malaria control require projections based on integrated models that can accommodate complex interactions of both climatic and non-climatic factors that define malaria landscape. In this paper, we combined

Spallation sources create a large amount of neutrons with energies up to the GeV range. To shield for these neutrons, steel and concrete are important materials. By adding different aggregates to normal concrete, one can improve the shielding effect of the concrete. Some of these aggregates can influence the rate of hydration (reaction) of the cement or even completely inhibit the hydration. It is

We study the point process given by the set of real zeros of random series generated with orthonormal bases of reproducing kernels of de Branges spaces. We find an explicit formula for the intensity function in terms of the phase of the Hermite-Biehler function generating the de Branges space. We prove that the intensity of the point process completely characterizes the underlying de Branges space

Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterizatio

The Drosophila antenna contains receptor neurons for mechanical, olfactory, thermal, and humidity stimuli. Neurons expressing the ionotropic receptor IR40a have been implicated in the selection of an appropriate humidity range [], but although previous work indicates that insect hygroreceptors may be made up by a "triad" of neurons (with a dry-, a cold-, and a humid-air-responding cell []), IR40a

The alcoholysis of triolein was used to explore the specific features of a recombinant Rhizopus oryzae lipase (rROL) for biodiesel synthesis. For this purpose, different acylglycerols were compared as substrates in lipase-catalysed transesterification. rROL was shown to exhibit a higher specificity towards 1-monoolein than triolein compared to other R. oryzae lipases, being more than 4-fold more s

The long-chain members of the lead(ii) alkanoate series or soaps, from octanoate to octadecanoate, have been thoroughly characterized by means of XRD, PDF analysis, DSC, FTIR, ssNMR and other techniques, in all their phases and mesophases. The crystal structures at room temperature of all of the members of the series are now solved, showing the existence of two polymorphic forms in the room temper

This paper aims to explore how learning about Circular Economy (CE) may be facilitated through the use of the serious game In the Loop. Despite the growing literature base related to CE, academic reflection on education for a CE is currently limited. In the Loop was developed to provide an experiential learning situation for educating about material criticality and CE. This study reflects on the u

Using quasi-simultaneous insitu PXRD and XANES, the direct correlation between the oxidation state of Cu ions in the commercially relevant deNOx NH3-SCR zeolite catalyst Cu-CHA and the Cu ion migration in the zeolitic pores was revealed during catalytic activation experiments. A comparison with recent reports further reveals the high sensitivity of the redox-active centers concerning heating rates

Familial dilated cardiomyopathy is a rare cause of dilated cardiomyopathy (DCM), especially in childhood. Our aim was to describe the clinical course and the genetic variants in a family where the proband was a four-month-old infant presenting with respiratory problems due to DCM. In the family, there was a strong family history of DCM and sudden cardiac death in four generations. DNA was analyzed

The ATLAS (one of two general purpose detectors at the LHC) Transition Radiation Tracker (TRT) is the outermost of the three tracking subsystems of the ATLAS Inner Detector. It is a large straw-based detector and contains about 350,000 electronics channels. The performance of the TRT as tracking and particularly particle identification detector strongly depends on stability of the operation parame

Objective The effect of a common polymorphism in the Growth Hormone (GH) receptor (d3-GHR) gene on growth, metabolism and body composition was examined in short children born small for gestational age (SGA) on GH treatment. Design In 96 prepubertal, short SGA children treated with high-dose GH (67 μg/kg/day) in the NESGAS study, insulin sensitivity (IS), insulin secretion and disposition index (DI