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Poor Treatment Compliance in Children With Down Syndrome and Acute Lymphoblastic Leukemia
Unique cytological features and chromosome aberrations in chondroid lipoma: a case report based on fine-needle aspiration cytology, histopathology, electron microscopy, chromosome banding, and molecular cytogenetics
Chondroid lipoma is a rare, benign tumor that may mimic soft-tissue sarcoma clinically. Its histopathologic features may resemble hibernoma, myxoid liposarcoma, myxoid chondrosarcoma, and other lipomatous or chondroid neoplasms. In this study, a chondroid lipoma was analyzed by fine-needle aspiration cytology, histopathology, electron microscopy, chromosome banding, and metaphase fluorescence in s
Vitrectomy Seems to be Beneficial for Advanced Diffuse Diabetic Macular Oedema not Responding to Laser Treatment.
Vibronic coupling in the ground and excited states of the naphthalene cation
The hole - vibrational coupling in naphthalene is studied using high-resolution gas-phase photoelectron spectroscopy and density functional theory calculations (DFT), and a remarkable increase of the coupling with low-frequency vibrations is observed in the excited states.
In vivo labeling of neuroblasts in the subventricular zone of rats.
Altered AP-1/Ref-1 redox pathway and reduced proliferative response in iNOS-deficient vascular smooth muscle cells
We previously reported that injury-induced medial vascular smooth muscle cell (VSMC) proliferation and neointima formation in carotid arteries of inducible nitric oxide synthase knockout ( iNOS KO) mice were significantly reduced compared with wild type (WT). However, the molecular pathway underlying such differences is not known. In this in vitro study, we discovered that the AP-1/Ref-1/thioredox
Mutated V-H genes and preferential V(H)3-21 use define new subsets of mantle cell lymphoma
Mantle cell lymphoma (MCL) is believed to originate from a naive B cell. However, we recently demonstrated that a subset of MCL displayed mutated V-H genes. We also reported restricted use of certain V-H genes. To assess the prognostic impact of these new findings, we performed V-H gene analysis of 110 patients, revealing that 18 (16%) patients had mutated and 92 (84%) patients had unmutated V-H g
No evidence of glucocorticosteroid-induced apoptosis of airway epithelial cells in vivo
Characterization of a transient collisional Ni-like molybdenum soft x-ray laser pumped in grazing incidence
We present experimental results from an extensive investigation of a Ni-like Mo X-ray laser pumped in the transient regime and GRIP configuration (GRazing Incidence Pumping). The pump laser is a 10 Hz, 1 J, Ti:Sa laser system. The main diagnostic is a monochromatic near-field imaging system with a 1.7 micron spatial resolution that shows the soft x-ray laser source size and position relative to th
Redox chemistry of a dimanganese(II,III) complex with an unsymmetric ligand: Water binding, deprotonation and accumulative light-induced oxidation
A dinuclear manganese complex {[(Mn2L)-L-II,IIII(mu-OAc)(2)]-ClO4} has been synthesised, where L is the dianion of 2-{[bis-(pyrid-2-ylmethyl)amino]methyl}-6-{[(3,5-di-tert-butyl-2- hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl)-4-methylphenol, an unsymmetric binucleating ligand with two coordinating phenol groups. The two manganese ions, with a Mn-Mn distance of 3.498 angstrom, are bridged by the t
Neurobiology in primary headaches.
Primary headaches such as migraine and cluster headache are neurovascular disorders. Migraine is a painful, incapacitating disease that affects a large portion of the adult population with a substantial economic burden on society. The disorder is characterised by recurrent unilateral headaches, usually accompanied by nausea, vomiting, photophobia, and/or phonophobia. A number of hypothesis have em
How Can I Become a Responsible Subject? Towards a Practice-Based Ethics of Responsiveness
Approaches to business ethics can be roughly divided into two streams: aEuro(1)codes of behavior' and aEuro(1)forms of subjectification', with code-oriented approaches clearly dominating the field. Through an elaboration of poststructuralist approaches to moral philosophy, this paper questions the emphasis on codes of behaviour and, thus, the conceptions of the moral and responsible subject that a
Locus-specific multifluor FISH analysis allows physical characterization of complex chromosome abnormalities in neoplasia
Novel techniques in molecular cytogenetics have radically improved the ability to characterize genetic changes in neoplastic cells. In parallel, a rapid development in high-throughput genomics has resulted in detailed physical maps of the human genome. Combining these two fields, we have developed a method for the simultaneous visualization of several physically defined segments along a chromosome
Hydrodynamical simulations of convection-related stellar micro-variability
We used a series of CO5BOLD hydrodynamical model atmospheres covering stellar objects from white dwarfs to red giants to derive theoretical estimates of the photometric and photocentric stellar variability in wavelength-integrated light across the Hertzsprung-Russell diagram. We validated our models against solar measurements from the SoHO/VIRGO instrument. Within our set of models we find a syste
Role-play assessment of social skills in conduct disordered and substance abusing adolescents: An empirical review.
Theoretical study of the unusual potential energy curve of the A (1)Sigma(+) state of AgH
The A (1)Sigma(+) potential energy curve of AgH is studied by means of the second-order multistate multireference perturbation theory including the spin-orbit and relativistic effects. The anomalous behavior of the vibrational energy levels observed in experiment is reproduced well by theory. An analysis of the A (1)Sigma(+) wave function shows that at the internuclear distance of 4-6 Angstrom, a
Stability of successful long-term adjustment in alcohol dependence: a follow-up study 15 years after the first long-term follow-up.
Expression of prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in ileum and other extraprostatic tissues
Prostate-specific antigen (PSA) is a widely used marker for prostate cancer. In the literature, there are reports of nonprostatic expression of PSA that potentially can affect early diagnosis. However, the results are scattered and inconclusive, which motivated us to conduct a more comprehensive study of the tissue distribution of PSA and the closely related protein human glandular kallikrein 2 (h