The objective of the study was to investigate the antigen specificity and occurrence of individual autoantibodies in mothers of children diagnosed with atrioventricular (AV) block in a nation-wide setting. Patients with AV block detected before 15 years of age were identified using national quality registries as well as a network of pediatric and adult cardiologists and rheumatologists at the six

ABSTRACT: BACKGROUND: Cerebral ischemia results in a rapid increase in contractile cerebrovascular receptors, such as the 5-hydroxytryptamine type 1B (5-HT1B), angiotensin II type 1 (AT1), and endothelin type B (ETB) receptors, in the vessel walls within the ischemic region, which further impairs local blood flow and aggravates tissue damage. This receptor upregulation occurs via activation of the

Popular Abstract in Swedish För att vi ska kunna lösa globala problem som miljöförstöring och fattigdom är det många som menar att den privata sektorn måste involveras på ett aktivt sätt. I den här avhandlingen, som består av en introduktion och fem vetenskapliga artiklar som tidigare publicerats i internationella tidskrifter, studeras ett exempel på hur privata aktörer faktiskt redan involverats It is commonly argued that the private sector needs to become actively involved for society to stand a chance of solving the most pressing global problems. This thesis, consisting of five articles previously published in refereed journals and an introductory essay, studies one case of private actor participation in global environmental governance: the Kyoto Protocol’s Clean Development Mechanism (

To estimate in gynecologically asymptomatic postmenopausal women with and without hormone replacement therapy (HRT) the prevalence at transvaginal ultrasound examination of 1) endometrial thickness ≥5.0mm, 2) intrauterine focal lesions if endometrial thickness ≥5.0mm, and 3) premalignant and malignant changes in the endometrium if endometrial thickness is ≥5.0mm and intrauterine focal lesions are

The partitioning of fluid flows among small and ultrasmall pores of the three-pore model in peritoneal dialysis has been traditionally assessed using 4-hour dwells with 3.86% glucose solutions. Under these conditions, however, back-filtration through small pores has been hard to demonstrate. As nicely shown by Asghar and Davies, however, the use of low-concentration (1.36%) glucose-based solutions

A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used fo

Under sommaren 2012 har nationellt resurscentrum för fysik (nrCf) varit involverat i flera aktiviteter där lärare fått tillfälle att interagera med forskare. aktiviteterna har haft både olika innehållsfokus och olika format för växelverkan, som kan ge inspiration till framtida aktiviteter.

The human papillomavirus (HPV) life cycle is strictly linked to the differentiation program of the infected mucosal epithelial cell. In the basal and lower levels of the epithelium, early genes coding for pro-mitotic proteins and viral replication factors are expressed, while terminal cell differentiation is required for activation of late gene expression and production of viral particles at the v

Downtimes in a manufacturing cell, a production line or an individual machine are characterized by a complex statistical behavior that their frequency and duration display. The work reported here concerns likenesses and differences between various statistical distributions that apply to functional times (TBF) and downtimes (DT) in connection with different discrete manufacturing processes. The TBF

Few studies have examined the association between LS in the oldest-old and not only health-related, but also psychological and socio-economical factors. The aim of this study was to examine LS in relation to functional capacity, locus of control (LoC) health status and other factors previously known to influence LS in the oldest-old. The study population consisted of 681 individuals aged 78-98 yea