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Cardiovascular morbidity and mortality remain similar in two cohorts of patients with long-standing rheumatoid arthritis seen in 1978 and 1995 in Malmo, Sweden.

Objective. Patients with RA have an increased risk of cardiovascular disease. Management of RA has changed substantially over time. Our aim was to evaluate changes in cardiovascular morbidity and mortality over the period of 1978-2002. Methods. Two cohorts of consecutive patients with RA seen at outpatient clinics in Malmö, Sweden, were started in 1978 (n = 148) and 1995 (n = 161) and compared wit

Bone mineral accrual and gain in skeletal width in pre-pubertal school children is independent of the mode of school transportation - one-year data from the prospective observational pediatric osteoporosis prevention (POP) study.

Background: Walking and cycling to school could be an important regular source of physical activity in growing children. The aim of this 12 months prospective observational study was thus to evaluate the effect of self-transportation to school on bone mineral accrual and gain in bone width in pre-pubertal children, both traits independently contributing to bone strength. Methods: Ninety-seven girl

Hemodynamic and histological effects of traumatic brain injury in eNOS-deficient mice.

Microvascular dysfunction in the brain, characterized by vasoconstriction, vascular occlusion, and disruption of the blood brain barrier, may adversely affect outcome following traumatic brain injury (TBI). Because of its vasodilating and antiaggregative properties, nitric oxide (NO) produced by nitric oxide synthase in the endothelium (eNOS) is a key regulator of vascular homeostasis. The objecti

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Ambiguous churches of the Baltic Sea: Nylars on Bornholm is used as a point of departure in a discussion of the so-called defensive churches or multi-functional churches at the Baltic Sea. The categorization of medieval society into four separate spheres, the church, the castle, the town and the countryside, is criticised as having created a heterogenous group of deviant churches. The deviant chur

Asymtomatic Bacteriuria as a Model to Study the Coevolution of Hosts and Bacteria.

During asymptomatic bacteriuria (ABU), bacteria colonize the urinary tract for extended periods of time without causing symptoms of urinary tract infection. Previous studies indicate that many Escherichia coli (E. coli) strains that cause ABU have evolved from uropathogenic E. coli (UPEC) by reductive evolution and loss of the ability to express functional virulence factors. For instance, the prot