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Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer.

Many studies have shown that primary prostate cancers are multifocal and are composed of multiple genetically distinct cancer cell clones. Whether or not multiclonal primary prostate cancers typically give rise to multiclonal or monoclonal prostate cancer metastases is largely unknown, although studies at single chromosomal loci are consistent with the latter case. Here we show through a high-reso

Så blev kapitalismen senil

Arena har mött Michael Hardt och Samir Amin, två av världens mest kända systemkritiker, i ett samtal om framtiden.

Awareness among nurses about reporting of adverse drug reactions in Sweden.

BACKGROUND: The purpose of this study was to investigate awareness among nurses regarding their new role as reporters of adverse drug reactions in Sweden and factors that may influence reporting by nurses. METHODS: In 2007, all nurses were included in the adverse drug reaction reporting scheme in Sweden. A questionnaire was sent to 753 randomly selected nurses in September 2010. RESULTS: Of

Investigation of Shifts and Interaction of Signals In High-contrast Transmission Spectroscopy

In the recently introduced high-contrast transmission version of saturated absorption laser spectroscopy, narrow signals are obtained from dense atomic samples subject to strong pumping. A study of possible systematic shifts of the signals in this domain of rather extreme experimental conditions was performed in order to assess the validity of spectroscopic data obtained with this technique. Certa

Private Criticism in the Public Sphere: Personal Writing on Literature in Readers' Reviews on Amazon

The article studies the character of general readers’ reviews on the internet bookstore Amazon; what is called private criticism. Patterns, common features, and contradictions are explored, and the social position and meaning of new forms of readers’ expressions is discussed. One part of the thesis is that the freedom of speech in the public sphere has given readers new and different opportunities

Microscopic theory for intersubband spontaneous emission

The amplified spontaneous emission spectra of quantum-cascade laser structures is computed with a Keldysh Green's functions theory. We show that the emission spectra are sharpened in comparison to gain spectra due to wave guide propagation. In addition the different dependence on level occupation causes moderate differences between gain and emission peak positions. Our fit-parameter-free theory is