Residual masses are frequently found in patients with aggressive lymphomas, following therapy. A study was undertaken to determine whether initial tumour size, changes during treatment, or size of the residual mass could provide prognostic information. Computed tomography (CT) examinations were carried out before, midway and after completion of chemotherapy in 37 patients with aggressive lymphoma

Popular Abstract in Swedish Modellering och simulering är etablerade tekniker för att lösa designproblem inom många olika ingenjörsdiscipliner idag. Dedicerade språk, såsom Modelica, och effektiva mjukvaror finns också tillgängliga. I denna avhandling presenteras en språklig utvidgning av Modelica, Optimica, som är avsedd för formulering av dynamiska optimeringsproblem. För att demonstrera användnModeling and simulation are established techniques for solving design problems in a wide range of engineering disciplines today. Dedicated computer languages, such as Modelica, and efficient software tools are available. In this thesis, an extension of Modelica, Optimica, targeted at dynamic optimization of Modelica models is proposed. In order to demonstrate the Optimica extension, supporting sof

It is of increasing importance to develop efficient purification methods for recombinant proteins where the number of steps can be minimised. The aim has been to establish a method for predicting the partitioning of the wild-type target protein in an aqueous two-phase system, and with this as basis, develop fusion tags and optimise the phase system for enhanced partitioning of the target protein.

Spatial heterogeneity of hydraulic and sorptive processes may have a strong impact on the mobility of bacteria in porous soils. Whereas heterogeneity at the microscopic solid particle/interstitial pore scale has been conceptually addressed by dividing the porous material into two or more coexisting sorbing fractions, field-scale spatial variability has been approached by developing stochastic meth

The forward-backward asymmetries of the processes e(+) e(-) --> Z --> b (b) over bar and e(+)e(-) --> Z --> c (c) over bar were measured from a sample of hadronic Z decays collected by the DELPHI experiment between 1993 and 1995. Enriched samples of b (b) over bar and c (c) over bar events were obtained using lifetime information. The tagging of b and c quarks in these samples was based on the sem

Due to the strongly kinetic nature of the chemical events leading to the formation of mesoscopically ordered inorganic-surfactant composite materials, detailed studies on the interdependency between the degree of inorganic condensation and the co-operative self-assembly is difficult to perform. We have therefore undertaken a study where organic polyelectrolytes are used as models for the inorganic

The view on reactive oxygen species (ROS) in inflammation is currently shifting from being considered damaging toward having a more complex role in regulating inflammatory reactions. We recently demonstrated a role of ROS in regulation of animal models for the autoimmune disease rheumatoid arthritis. Low levels of ROS production, due to a mutation in the Ncf1 gene coding for the Ncf1 (alias p47pho

Let beta > 1 be a real number and M : R --> GL(C-d) be a uniformly almost periodic matrix-valued function. We study the asymptotic behavior of the product P-n(x) = M(beta(n-1)x)...M(betax) M(x). Under some conditions we prove a theorem of Furstenberg-Kesten type for such products of non-stationary random matrices. Theorems of Kingman and Oseledec type are also proved. The obtained results are appl

This report is about the co-operation between the police and the social services in the specific situation when the social services apply for assistance for taking children and drug-abusers in to involuntary care immediately. The police have an authority to use violence that social workers do not have. Therefore social workers need the police to accomplish this task. The report aims to reach adeep

The long-lived, light-induced radical Y-D(.) of the Tyr161 residue in the D2 protein of Photosystem 11 (PSII) is known to magnetically interact with the CaMn4 cluster, situated similar to 30 angstrom away. In this study we report a transient step-change increase in YD EPR intensity upon the application of a single laser flash to S, state-synchronised PSII-enriched membranes from spinach. This tran

Gliomas are the most common primary brain tumors and offer a poor prognosis in patients because of their infiltrative and treatment-resistant nature. The median survival time after diagnosis is approximately 11-12 months. There is a strong need for novel treatment modalities in targeting gliomas, and recent advances use neural progenitor cells as delivery systems for different therapeutic strategi

Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) and anti-mu antibody was analyzed. Before treatment, the proportion of CD3+ and CD4

The linearly constrained minimum variance (LCMV) method, which allows multiple linear constraints, is an extension of the classical minimum variance distortionless response filter. Depending on the spatial filter length and the desired frequency grid, a direct computation of the resulting spatial beam pattern may be prohibitive. This brief exploits the rich structure of the LCMV expression to find